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PubMed:8392092 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-142 Sentence denotes Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate.
T1 0-142 Sentence denotes Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate.
T2 143-439 Sentence denotes We have previously shown that minimally oxidized LDL (MM-LDL) activated endothelial cells to increase their interaction with monocytes but not neutrophils, inducing monocyte but not neutrophil binding and synthesis of monocyte chemotactic protein-1 and monocyte colony-stimulating factor (M-CSF).
T2 143-439 Sentence denotes We have previously shown that minimally oxidized LDL (MM-LDL) activated endothelial cells to increase their interaction with monocytes but not neutrophils, inducing monocyte but not neutrophil binding and synthesis of monocyte chemotactic protein-1 and monocyte colony-stimulating factor (M-CSF).
T3 440-555 Sentence denotes In the present studies we have examined the signaling pathways by which this monocyte-specific response is induced.
T3 440-555 Sentence denotes In the present studies we have examined the signaling pathways by which this monocyte-specific response is induced.
T4 556-693 Sentence denotes Both induction of monocyte binding and mRNA levels for M-CSF by MM-LDL were not inhibited in protein kinase C-depleted endothelial cells.
T4 556-693 Sentence denotes Both induction of monocyte binding and mRNA levels for M-CSF by MM-LDL were not inhibited in protein kinase C-depleted endothelial cells.
T5 694-799 Sentence denotes A number of our studies indicate that cAMP is the second messenger for the effects of MM-LDL cited above.
T5 694-799 Sentence denotes A number of our studies indicate that cAMP is the second messenger for the effects of MM-LDL cited above.
T6 800-896 Sentence denotes Incubation of endothelial cells with MM-LDL caused a 173% increase in intracellular cAMP levels.
T6 800-896 Sentence denotes Incubation of endothelial cells with MM-LDL caused a 173% increase in intracellular cAMP levels.
T7 897-1040 Sentence denotes Agents which increased cAMP levels, including cholera toxin, pertussis toxin, dibutyryl cAMP, and isoproterenol mimicked the actions of MM-LDL.
T7 897-1040 Sentence denotes Agents which increased cAMP levels, including cholera toxin, pertussis toxin, dibutyryl cAMP, and isoproterenol mimicked the actions of MM-LDL.
T8 1041-1207 Sentence denotes Agents which elevated cAMP were also shown to activate NF kappa B, suggesting a role for this transcription factor in activation of monocyte-endothelial interactions.
T8 1041-1207 Sentence denotes Agents which elevated cAMP were also shown to activate NF kappa B, suggesting a role for this transcription factor in activation of monocyte-endothelial interactions.
T9 1208-1397 Sentence denotes Although endothelial leukocyte adhesion molecule (ELAM) mRNA synthesis can be regulated by NF kappa B, ELAM was not expressed and ELAM mRNA was only slightly elevated in response to MM-LDL.
T9 1208-1397 Sentence denotes Although endothelial leukocyte adhesion molecule (ELAM) mRNA synthesis can be regulated by NF kappa B, ELAM was not expressed and ELAM mRNA was only slightly elevated in response to MM-LDL.
T10 1398-1521 Sentence denotes We present evidence that induction of neutrophil binding by LPS is actually suppressed by agents that elevated cAMP levels.
T10 1398-1521 Sentence denotes We present evidence that induction of neutrophil binding by LPS is actually suppressed by agents that elevated cAMP levels.