| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-136 |
Sentence |
denotes |
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. |
| T1 |
0-136 |
Sentence |
denotes |
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. |
| T2 |
137-294 |
Sentence |
denotes |
The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd (TNFRp55) and 75 kd (TNFRp75). |
| T2 |
137-294 |
Sentence |
denotes |
The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd (TNFRp55) and 75 kd (TNFRp75). |
| T3 |
295-363 |
Sentence |
denotes |
Using gene targeting, we generated a TNFRp55-deficient mouse strain. |
| T3 |
295-363 |
Sentence |
denotes |
Using gene targeting, we generated a TNFRp55-deficient mouse strain. |
| T4 |
364-486 |
Sentence |
denotes |
Cells from TNFRp55-/-mutant mice lack expression of TNFRp55 but display normal numbers of high affinity TNFRp75 molecules. |
| T4 |
364-486 |
Sentence |
denotes |
Cells from TNFRp55-/-mutant mice lack expression of TNFRp55 but display normal numbers of high affinity TNFRp75 molecules. |
| T5 |
487-624 |
Sentence |
denotes |
Thymocyte development and lymphocyte populations are unaltered, and clonal deletion of potentially self-reactive T cells is not impaired. |
| T5 |
487-624 |
Sentence |
denotes |
Thymocyte development and lymphocyte populations are unaltered, and clonal deletion of potentially self-reactive T cells is not impaired. |
| T6 |
625-768 |
Sentence |
denotes |
However, TNF signaling is largely abolished, as judged by the failure of TNF to induce NF-kappa B in T lymphocytes from TNFRp55-deficient mice. |
| T6 |
625-768 |
Sentence |
denotes |
However, TNF signaling is largely abolished, as judged by the failure of TNF to induce NF-kappa B in T lymphocytes from TNFRp55-deficient mice. |
| T7 |
769-896 |
Sentence |
denotes |
The loss of TNFRp55 function renders mice resistant to lethal dosages of either lipopolysaccharides or S. aureus enterotoxin B. |
| T7 |
769-896 |
Sentence |
denotes |
The loss of TNFRp55 function renders mice resistant to lethal dosages of either lipopolysaccharides or S. aureus enterotoxin B. |
| T8 |
897-1014 |
Sentence |
denotes |
In contrast, TNFRp55-deficient mice are severely impaired to clear L. monocytogenes and readily succumb to infection. |
| T8 |
897-1014 |
Sentence |
denotes |
In contrast, TNFRp55-deficient mice are severely impaired to clear L. monocytogenes and readily succumb to infection. |
| T9 |
1015-1132 |
Sentence |
denotes |
Thus, the 55 kd TNFR plays a decisive role in the host's defense against microorganisms and their pathogenic factors. |
| T9 |
1015-1132 |
Sentence |
denotes |
Thus, the 55 kd TNFR plays a decisive role in the host's defense against microorganisms and their pathogenic factors. |