| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-57 |
Sentence |
denotes |
An interleukin-4-induced transcription factor: IL-4 Stat. |
| T1 |
0-57 |
Sentence |
denotes |
An interleukin-4-induced transcription factor: IL-4 Stat. |
| T2 |
58-174 |
Sentence |
denotes |
Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells. |
| T2 |
58-174 |
Sentence |
denotes |
Interleukin-4 (IL-4) is an immunomodulatory cytokine secreted by activated T lymphocytes, basophils, and mast cells. |
| T3 |
175-313 |
Sentence |
denotes |
It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1. |
| T3 |
175-313 |
Sentence |
denotes |
It plays an important role in modulating the balance of T helper (Th) cell subsets, favoring expansion of the Th2 lineage relative to Th1. |
| T4 |
314-456 |
Sentence |
denotes |
Imbalance of these T lymphocyte subsets has been implicated in immunological diseases including allergy, inflammation, and autoimmune disease. |
| T4 |
314-456 |
Sentence |
denotes |
Imbalance of these T lymphocyte subsets has been implicated in immunological diseases including allergy, inflammation, and autoimmune disease. |
| T5 |
457-576 |
Sentence |
denotes |
IL-4 may mediate its biological effects, at least in part, by activating a tyrosine-phosphorylated DNA binding protein. |
| T5 |
457-576 |
Sentence |
denotes |
IL-4 may mediate its biological effects, at least in part, by activating a tyrosine-phosphorylated DNA binding protein. |
| T6 |
577-641 |
Sentence |
denotes |
This protein has now been purified and its encoding gene cloned. |
| T6 |
577-641 |
Sentence |
denotes |
This protein has now been purified and its encoding gene cloned. |
| T7 |
642-860 |
Sentence |
denotes |
Examination of the primary amino acid sequence of this protein indicates that it is a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins, hereby designated IL-4 Stat. |
| T7 |
642-860 |
Sentence |
denotes |
Examination of the primary amino acid sequence of this protein indicates that it is a member of the signal transducers and activators of transcription (Stat) family of DNA binding proteins, hereby designated IL-4 Stat. |
| T8 |
861-1107 |
Sentence |
denotes |
Study of the inhibitory activities of phosphotyrosine-containing peptides derived from the intracellular domain of the IL-4 receptor provided evidence for direct coupling of receptor and transcription factor during the IL-4 Stat activation cycle. |
| T8 |
861-1107 |
Sentence |
denotes |
Study of the inhibitory activities of phosphotyrosine-containing peptides derived from the intracellular domain of the IL-4 receptor provided evidence for direct coupling of receptor and transcription factor during the IL-4 Stat activation cycle. |
| T9 |
1108-1225 |
Sentence |
denotes |
Such observations indicate that IL-4 Stat has the same functional domain for both receptor coupling and dimerization. |
| T9 |
1108-1225 |
Sentence |
denotes |
Such observations indicate that IL-4 Stat has the same functional domain for both receptor coupling and dimerization. |