| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-62 |
Sentence |
denotes |
C/EBP beta regulation of the tumor necrosis factor alpha gene. |
| T1 |
0-62 |
Sentence |
denotes |
C/EBP beta regulation of the tumor necrosis factor alpha gene. |
| T2 |
63-166 |
Sentence |
denotes |
Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases. |
| T2 |
63-166 |
Sentence |
denotes |
Activated macrophages contribute to chronic inflammation by the secretion of cytokines and proteinases. |
| T3 |
167-351 |
Sentence |
denotes |
Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion. |
| T3 |
167-351 |
Sentence |
denotes |
Tumor necrosis factor alpha (TNF alpha) is particularly important in this process because of its ability to regulate other inflammatory mediators in an autocrine and paracrine fashion. |
| T4 |
352-445 |
Sentence |
denotes |
The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known. |
| T4 |
352-445 |
Sentence |
denotes |
The mechanism(s) responsible for the cell type-specific regulation of TNF alpha is not known. |
| T5 |
446-564 |
Sentence |
denotes |
We present data to show that the expression of TNF alpha is regulated by the transcription factor C/EBP beta (NF-IL6). |
| T5 |
446-564 |
Sentence |
denotes |
We present data to show that the expression of TNF alpha is regulated by the transcription factor C/EBP beta (NF-IL6). |
| T6 |
565-726 |
Sentence |
denotes |
C/EBP beta activated the TNF alpha gene promoter in cotransfection assays and bound to it at a site which failed to bind the closely related protein C/EBP alpha. |
| T6 |
565-726 |
Sentence |
denotes |
C/EBP beta activated the TNF alpha gene promoter in cotransfection assays and bound to it at a site which failed to bind the closely related protein C/EBP alpha. |
| T7 |
727-833 |
Sentence |
denotes |
Finally, a dominant-negative version of C/EBP beta blocked TNF alpha promoter activation in myeloid cells. |
| T7 |
727-833 |
Sentence |
denotes |
Finally, a dominant-negative version of C/EBP beta blocked TNF alpha promoter activation in myeloid cells. |
| T8 |
834-930 |
Sentence |
denotes |
Our results implicate C/EBP beta as an important regulator of TNF alpha by myelomonocytic cells. |
| T8 |
834-930 |
Sentence |
denotes |
Our results implicate C/EBP beta as an important regulator of TNF alpha by myelomonocytic cells. |
