> top > projects > Inflammaging > docs > PubMed:7849291 > annotations
Inflammaging  

PubMed:7849291 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-86 Sentence denotes Posttranscriptional regulation of macrophage tissue factor expression by antioxidants.
T1 0-86 Sentence denotes Posttranscriptional regulation of macrophage tissue factor expression by antioxidants.
T2 87-277 Sentence denotes Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation.
T2 87-277 Sentence denotes Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation.
T3 278-500 Sentence denotes Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1.
T3 278-500 Sentence denotes Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1.
T4 501-653 Sentence denotes The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes.
T4 501-653 Sentence denotes The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes.
T5 654-853 Sentence denotes Both pyrrolidine dithiocarbamate, an oxidant scavenger, and N-acetyl-cysteine, a precursor of the endogenous antioxidant glutathione, inhibited stimulation of macrophage procoagulant activity by LPS.
T5 654-853 Sentence denotes Both pyrrolidine dithiocarbamate, an oxidant scavenger, and N-acetyl-cysteine, a precursor of the endogenous antioxidant glutathione, inhibited stimulation of macrophage procoagulant activity by LPS.
T6 854-1024 Sentence denotes Northern blot analysis showed that neither of these agents reduced LPS-stimulated TF mRNA accumulation, thereby suggesting a posttranscriptional mechanism for the effect.
T6 854-1024 Sentence denotes Northern blot analysis showed that neither of these agents reduced LPS-stimulated TF mRNA accumulation, thereby suggesting a posttranscriptional mechanism for the effect.
T7 1025-1245 Sentence denotes Immunofluorescence studies of human monocytes using polyclonal anti-TF antibody showed that N-acetyl-cysteine treatment prevented the characteristic plasmalemmal localization of TF antigen that occurs in response to LPS.
T7 1025-1245 Sentence denotes Immunofluorescence studies of human monocytes using polyclonal anti-TF antibody showed that N-acetyl-cysteine treatment prevented the characteristic plasmalemmal localization of TF antigen that occurs in response to LPS.
T8 1246-1450 Sentence denotes Western blot analysis showed that N-acetyl-cysteine reduced the accumulation of the 47-kD mature glycoprotein in LPS-treated cells, a finding consistent with the results of the immunofluorescence studies.
T8 1246-1450 Sentence denotes Western blot analysis showed that N-acetyl-cysteine reduced the accumulation of the 47-kD mature glycoprotein in LPS-treated cells, a finding consistent with the results of the immunofluorescence studies.
T9 1451-1546 Sentence denotes Furthermore, these conditions did not result in an accumulation of the less mature forms of TF.
T9 1451-1546 Sentence denotes Furthermore, these conditions did not result in an accumulation of the less mature forms of TF.
T10 1547-1713 Sentence denotes When considered together, these data suggest that antioxidants exert their effects by impairing translation and/or by causing degradation of newly translated protein.
T10 1547-1713 Sentence denotes When considered together, these data suggest that antioxidants exert their effects by impairing translation and/or by causing degradation of newly translated protein.
T11 1714-1907 Sentence denotes The effect of antioxidants on tumor necrosis factor appeared to be species specific, with no effect on LPS-induced tumor necrosis factor in murine cells, but with inhibition in human monocytes.
T11 1714-1907 Sentence denotes The effect of antioxidants on tumor necrosis factor appeared to be species specific, with no effect on LPS-induced tumor necrosis factor in murine cells, but with inhibition in human monocytes.
T12 1908-2071 Sentence denotes The posttranscriptional effect of antioxidants on TF expression data suggests a novel mechanism whereby these agents might modulate monocyte/macrophage activation.
T12 1908-2071 Sentence denotes The posttranscriptional effect of antioxidants on TF expression data suggests a novel mechanism whereby these agents might modulate monocyte/macrophage activation.