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PubMed:5675437 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T1 0-60 Sentence denotes Studies on the anti-inflammatory action of 6-mercaptopurine.
T1 0-60 Sentence denotes Studies on the anti-inflammatory action of 6-mercaptopurine.
T2 61-246 Sentence denotes The mechanism of action of 6-mercaptopurine (6-MP) on an egg albumin-induced inflammatory lesion in the skin has been studied in rabbits treated with 6-MP in a daily dosage of 18 mg/kg.
T2 61-246 Sentence denotes The mechanism of action of 6-mercaptopurine (6-MP) on an egg albumin-induced inflammatory lesion in the skin has been studied in rabbits treated with 6-MP in a daily dosage of 18 mg/kg.
T3 247-541 Sentence denotes Relative to control animals, significant decreases in the numbers of large lymphocytes and monocytes in the blood were observed in the 6-MP-treated animals by the 9th day of treatment, without significant decrease in the numbers of polymorphonuclear leukocytes and small and medium lymphocytes.
T3 247-541 Sentence denotes Relative to control animals, significant decreases in the numbers of large lymphocytes and monocytes in the blood were observed in the 6-MP-treated animals by the 9th day of treatment, without significant decrease in the numbers of polymorphonuclear leukocytes and small and medium lymphocytes.
T4 542-671 Sentence denotes Concurrently, a significant decrease was also seen in the percentage of tissue mononuclear cells in the inflammatory skin lesion.
T4 542-671 Sentence denotes Concurrently, a significant decrease was also seen in the percentage of tissue mononuclear cells in the inflammatory skin lesion.
T5 672-813 Sentence denotes There was a highly significant correlation between the numbers of monocytes in the blood and the per cent of mononuclear cells in the lesion.
T5 672-813 Sentence denotes There was a highly significant correlation between the numbers of monocytes in the blood and the per cent of mononuclear cells in the lesion.
T6 814-972 Sentence denotes A mean of 52% of the mononuclear cells in the tissue lesion phagocytosed carbon offering further evidence that the major cell involved was the blood monocyte.
T6 814-972 Sentence denotes A mean of 52% of the mononuclear cells in the tissue lesion phagocytosed carbon offering further evidence that the major cell involved was the blood monocyte.
T7 973-1149 Sentence denotes In vitro incorporation of (3)H-Tdr by blood mononuclear cells was significantly reduced in the 6-MP-treated animals as determined by scintillation counting and radioautography.
T7 973-1149 Sentence denotes In vitro incorporation of (3)H-Tdr by blood mononuclear cells was significantly reduced in the 6-MP-treated animals as determined by scintillation counting and radioautography.
T8 1150-1228 Sentence denotes The large lymphocyte was the predominant cell type which was labeled in vitro.
T8 1150-1228 Sentence denotes The large lymphocyte was the predominant cell type which was labeled in vitro.
T9 1229-1281 Sentence denotes Small lymphocytes and monocytes were rarely labeled.
T9 1229-1281 Sentence denotes Small lymphocytes and monocytes were rarely labeled.
T10 1282-1599 Sentence denotes The data obtained suggest that the anti-inflammatory effect of 6-MP, reflected in these experiments by a decrease in mononuclear cells in a tissue lesion, results from suppression of a bone marrow response to local inflammation, affecting principally proliferating precursors of blood monocytes and large lymphocytes.
T10 1282-1599 Sentence denotes The data obtained suggest that the anti-inflammatory effect of 6-MP, reflected in these experiments by a decrease in mononuclear cells in a tissue lesion, results from suppression of a bone marrow response to local inflammation, affecting principally proliferating precursors of blood monocytes and large lymphocytes.
T11 1600-1730 Sentence denotes The possible importance of this action of 6-MP in the treatment of inflammatory and immunologically mediated disease is discussed.
T11 1600-1730 Sentence denotes The possible importance of this action of 6-MP in the treatment of inflammatory and immunologically mediated disease is discussed.