| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-110 |
Sentence |
denotes |
The effect of bacterial products on synovial fibroblast function: hypermetabolic changes induced by endotoxin. |
| T1 |
0-110 |
Sentence |
denotes |
The effect of bacterial products on synovial fibroblast function: hypermetabolic changes induced by endotoxin. |
| T2 |
111-200 |
Sentence |
denotes |
The effects of bacterial products on selected synovial fibroblast functions were studied. |
| T2 |
111-200 |
Sentence |
denotes |
The effects of bacterial products on selected synovial fibroblast functions were studied. |
| T3 |
201-405 |
Sentence |
denotes |
Extracts of commonly encountered microorganisms were prepared by sonic or mechanical disruption. "Purified" endotoxins were prepared from selected organisms, and in some cases were purchased commercially. |
| T3 |
201-405 |
Sentence |
denotes |
Extracts of commonly encountered microorganisms were prepared by sonic or mechanical disruption. "Purified" endotoxins were prepared from selected organisms, and in some cases were purchased commercially. |
| T4 |
406-510 |
Sentence |
denotes |
Normal fibroblasts were derived from synovial connective tissue obtained from amputations or arthrotomy. |
| T4 |
406-510 |
Sentence |
denotes |
Normal fibroblasts were derived from synovial connective tissue obtained from amputations or arthrotomy. |
| T5 |
511-610 |
Sentence |
denotes |
The cells were grown as a monolayer on glass and were nourished by a semisynthetic nutrient medium. |
| T5 |
511-610 |
Sentence |
denotes |
The cells were grown as a monolayer on glass and were nourished by a semisynthetic nutrient medium. |
| T6 |
611-766 |
Sentence |
denotes |
Extracts of Gram-negative bacteria, applied to fibroblast cultures, markedly increased hyaluronic acid production, glucose utilization, and lactate output. |
| T6 |
611-766 |
Sentence |
denotes |
Extracts of Gram-negative bacteria, applied to fibroblast cultures, markedly increased hyaluronic acid production, glucose utilization, and lactate output. |
| T7 |
767-884 |
Sentence |
denotes |
Treatment of the extracts with heat at 100 degrees C for (1/2) hr decreased their effectiveness by approximately 40%. |
| T7 |
767-884 |
Sentence |
denotes |
Treatment of the extracts with heat at 100 degrees C for (1/2) hr decreased their effectiveness by approximately 40%. |
| T8 |
885-1030 |
Sentence |
denotes |
Purified Gram-negative bacterial endotoxin stimulated synovial fibroblasts to an extent comparable to that caused by heat-treated whole extracts. |
| T8 |
885-1030 |
Sentence |
denotes |
Purified Gram-negative bacterial endotoxin stimulated synovial fibroblasts to an extent comparable to that caused by heat-treated whole extracts. |
| T9 |
1031-1148 |
Sentence |
denotes |
The lipid moiety of the endotoxin molecule appeared to account for much of the stimulatory activity of the endotoxin. |
| T9 |
1031-1148 |
Sentence |
denotes |
The lipid moiety of the endotoxin molecule appeared to account for much of the stimulatory activity of the endotoxin. |
| T10 |
1149-1257 |
Sentence |
denotes |
Extracts of commonly encountered Gram-positive cocci, yeast, and Mycoplasma had no stimulating capabilities. |
| T10 |
1149-1257 |
Sentence |
denotes |
Extracts of commonly encountered Gram-positive cocci, yeast, and Mycoplasma had no stimulating capabilities. |
| T11 |
1258-1328 |
Sentence |
denotes |
Corynebacterial extracts, however, had definite stimulating potential. |
| T11 |
1258-1328 |
Sentence |
denotes |
Corynebacterial extracts, however, had definite stimulating potential. |
| T12 |
1329-1430 |
Sentence |
denotes |
Endotoxin-synovial cell interaction experiments demonstrated that endotoxin was bound to fibroblasts. |
| T12 |
1329-1430 |
Sentence |
denotes |
Endotoxin-synovial cell interaction experiments demonstrated that endotoxin was bound to fibroblasts. |
| T13 |
1431-1538 |
Sentence |
denotes |
Reassay of the endotoxin after extraction from the cells showed that it retained its stimulatory potential. |
| T13 |
1431-1538 |
Sentence |
denotes |
Reassay of the endotoxin after extraction from the cells showed that it retained its stimulatory potential. |
| T14 |
1539-1677 |
Sentence |
denotes |
The metabolic phenomena stimulated by bacterial products duplicate the major known actions of connective tissue-activating peptide (CTAP). |
| T14 |
1539-1677 |
Sentence |
denotes |
The metabolic phenomena stimulated by bacterial products duplicate the major known actions of connective tissue-activating peptide (CTAP). |
| T15 |
1678-1897 |
Sentence |
denotes |
The observations made in this study suggest that bacterial products may participate in a fundamental way in the activation process, and indicate a possible role for bacterial products in synovial inflammation in humans. |
| T15 |
1678-1897 |
Sentence |
denotes |
The observations made in this study suggest that bacterial products may participate in a fundamental way in the activation process, and indicate a possible role for bacterial products in synovial inflammation in humans. |