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PubMed:35207567 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T1 0-27 Sentence denotes Omics and Male Infertility:
T1 0-27 Sentence denotes Omics and Male Infertility:
T2 28-80 Sentence denotes Highlighting the Application of Transcriptomic Data.
T2 28-80 Sentence denotes Highlighting the Application of Transcriptomic Data.
T3 81-191 Sentence denotes Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples.
T3 81-191 Sentence denotes Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples.
T4 192-449 Sentence denotes Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, medical records and physical examinations, which of course are fundamental, but yet inefficient, because 30% of male infertility cases remain idiopathic.
T4 192-449 Sentence denotes Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, medical records and physical examinations, which of course are fundamental, but yet inefficient, because 30% of male infertility cases remain idiopathic.
T5 450-583 Sentence denotes This dilemmatic status of the unknown needs to be addressed with more sophisticated and result-driven technologies and/or techniques.
T5 450-583 Sentence denotes This dilemmatic status of the unknown needs to be addressed with more sophisticated and result-driven technologies and/or techniques.
T6 584-739 Sentence denotes Genetic alterations have been linked with male infertility, thereby unveiling the practicality of investigating this disorder from the "omics" perspective.
T6 584-739 Sentence denotes Genetic alterations have been linked with male infertility, thereby unveiling the practicality of investigating this disorder from the "omics" perspective.
T7 740-1014 Sentence denotes Omics aims at analyzing the structure and functions of a whole constituent of a given biological function at different levels, including the molecular gene level (genomics), transcript level (transcriptomics), protein level (proteomics) and metabolites level (metabolomics).
T7 740-1014 Sentence denotes Omics aims at analyzing the structure and functions of a whole constituent of a given biological function at different levels, including the molecular gene level (genomics), transcript level (transcriptomics), protein level (proteomics) and metabolites level (metabolomics).
T8 1015-1244 Sentence denotes In the current study, an overview of the four branches of omics and their roles in male infertility are briefly discussed; the potential usefulness of assessing transcriptomic data to understand this pathology is also elucidated.
T8 1015-1244 Sentence denotes In the current study, an overview of the four branches of omics and their roles in male infertility are briefly discussed; the potential usefulness of assessing transcriptomic data to understand this pathology is also elucidated.
T9 1245-1463 Sentence denotes After assessing the publicly obtainable transcriptomic data for datasets on male infertility, a total of 1385 datasets were retrieved, of which 10 datasets met the inclusion criteria and were used for further analysis.
T9 1245-1463 Sentence denotes After assessing the publicly obtainable transcriptomic data for datasets on male infertility, a total of 1385 datasets were retrieved, of which 10 datasets met the inclusion criteria and were used for further analysis.
T10 1464-1561 Sentence denotes These datasets were classified into groups according to the disease or cause of male infertility.
T10 1464-1561 Sentence denotes These datasets were classified into groups according to the disease or cause of male infertility.
T11 1562-1781 Sentence denotes The groups include non-obstructive azoospermia (NOA), obstructive azoospermia (OA), non-obstructive and obstructive azoospermia (NOA and OA), spermatogenic dysfunction, sperm dysfunction, and Y chromosome microdeletion.
T11 1562-1781 Sentence denotes The groups include non-obstructive azoospermia (NOA), obstructive azoospermia (OA), non-obstructive and obstructive azoospermia (NOA and OA), spermatogenic dysfunction, sperm dysfunction, and Y chromosome microdeletion.
T12 1782-1933 Sentence denotes Findings revealed that 8 genes (LDHC, PDHA2, TNP1, TNP2, ODF1, ODF2, SPINK2, PCDHB3) were commonly differentially expressed between all disease groups.
T12 1782-1933 Sentence denotes Findings revealed that 8 genes (LDHC, PDHA2, TNP1, TNP2, ODF1, ODF2, SPINK2, PCDHB3) were commonly differentially expressed between all disease groups.
T13 1934-2437 Sentence denotes Likewise, 56 genes were common between NOA versus NOA and OA (ADAD1, BANF2, BCL2L14, C12orf50, C20orf173, C22orf23, C6orf99, C9orf131, C9orf24, CABS1, CAPZA3, CCDC187, CCDC54, CDKN3, CEP170, CFAP206, CRISP2, CT83, CXorf65, FAM209A, FAM71F1, FAM81B, GALNTL5, GTSF1, H1FNT, HEMGN, HMGB4, KIF2B, LDHC, LOC441601, LYZL2, ODF1, ODF2, PCDHB3, PDHA2, PGK2, PIH1D2, PLCZ1, PROCA1, RIMBP3, ROPN1L, SHCBP1L, SMCP, SPATA16, SPATA19, SPINK2, TEX33, TKTL2, TMCO2, TMCO5A, TNP1, TNP2, TSPAN16, TSSK1B, TTLL2, UBQLN3).
T13 1934-2437 Sentence denotes Likewise, 56 genes were common between NOA versus NOA and OA (ADAD1, BANF2, BCL2L14, C12orf50, C20orf173, C22orf23, C6orf99, C9orf131, C9orf24, CABS1, CAPZA3, CCDC187, CCDC54, CDKN3, CEP170, CFAP206, CRISP2, CT83, CXorf65, FAM209A, FAM71F1, FAM81B, GALNTL5, GTSF1, H1FNT, HEMGN, HMGB4, KIF2B, LDHC, LOC441601, LYZL2, ODF1, ODF2, PCDHB3, PDHA2, PGK2, PIH1D2, PLCZ1, PROCA1, RIMBP3, ROPN1L, SHCBP1L, SMCP, SPATA16, SPATA19, SPINK2, TEX33, TKTL2, TMCO2, TMCO5A, TNP1, TNP2, TSPAN16, TSSK1B, TTLL2, UBQLN3).
T14 2438-2686 Sentence denotes These genes, particularly the above-mentioned 8 genes, are involved in diverse biological processes such as germ cell development, spermatid development, spermatid differentiation, regulation of proteolysis, spermatogenesis and metabolic processes.
T14 2438-2686 Sentence denotes These genes, particularly the above-mentioned 8 genes, are involved in diverse biological processes such as germ cell development, spermatid development, spermatid differentiation, regulation of proteolysis, spermatogenesis and metabolic processes.
T15 2687-2801 Sentence denotes Owing to the stage-specific expression of these genes, any mal-expression can ultimately lead to male infertility.
T15 2687-2801 Sentence denotes Owing to the stage-specific expression of these genes, any mal-expression can ultimately lead to male infertility.
T16 2802-3022 Sentence denotes Therefore, currently available data on all branches of omics relating to male fertility can be used to identify biomarkers for diagnosing male infertility, which can potentially help in unravelling some idiopathic cases.
T16 2802-3022 Sentence denotes Therefore, currently available data on all branches of omics relating to male fertility can be used to identify biomarkers for diagnosing male infertility, which can potentially help in unravelling some idiopathic cases.