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PubMed:32712222 JSONTXT 21 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19.
T1 0-103 Sentence denotes Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19.
T2 104-115 Sentence denotes BACKGROUND:
T2 104-115 Sentence denotes BACKGROUND:
T3 116-227 Sentence denotes Obesity was recently identified as a major risk factor for worse COVID-19 severity, especially among the young.
T3 116-227 Sentence denotes Obesity was recently identified as a major risk factor for worse COVID-19 severity, especially among the young.
T4 228-359 Sentence denotes The reason why its impact seems to be less pronounced in the elderly may be due to the concomitant presence of other comorbidities.
T4 228-359 Sentence denotes The reason why its impact seems to be less pronounced in the elderly may be due to the concomitant presence of other comorbidities.
T5 360-431 Sentence denotes However, all reports only focus on BMI, an indirect marker of body fat.
T5 360-431 Sentence denotes However, all reports only focus on BMI, an indirect marker of body fat.
T6 432-584 Sentence denotes Aim To explore the impact on COVID-19 severity of abdominal fat as a marker of body composition easily collected in patients undergoing a chest CT scan.
T6 432-584 Sentence denotes Aim To explore the impact on COVID-19 severity of abdominal fat as a marker of body composition easily collected in patients undergoing a chest CT scan.
T7 585-593 Sentence denotes METHODS:
T7 585-593 Sentence denotes METHODS:
T8 594-811 Sentence denotes Patients included in this retrospective study were consecutively enrolled among those admitted to an Emergency Department in Rome, Italy, who tested positive for SARS-Cov-2 and underwent a chest CT scan in March 2020.
T8 594-811 Sentence denotes Patients included in this retrospective study were consecutively enrolled among those admitted to an Emergency Department in Rome, Italy, who tested positive for SARS-Cov-2 and underwent a chest CT scan in March 2020.
T9 812-864 Sentence denotes Data were extracted from electronic medical records.
T9 812-864 Sentence denotes Data were extracted from electronic medical records.
T10 865-873 Sentence denotes RESULTS:
T10 865-873 Sentence denotes RESULTS:
T11 874-938 Sentence denotes 150 patients were included (64.7% male, mean age 64 ± 16 years).
T11 874-938 Sentence denotes 150 patients were included (64.7% male, mean age 64 ± 16 years).
T12 939-1223 Sentence denotes Visceral fat (VAT) was significantly higher in patients requiring intensive care (p = .032), together with age (p = .009), inflammation markers CRP and LDH (p < .0001, p = .003, respectively), and interstitial pneumonia severity as assessed by a Lung Severity Score (LSS) (p < .0001).
T12 939-1223 Sentence denotes Visceral fat (VAT) was significantly higher in patients requiring intensive care (p = .032), together with age (p = .009), inflammation markers CRP and LDH (p < .0001, p = .003, respectively), and interstitial pneumonia severity as assessed by a Lung Severity Score (LSS) (p < .0001).
T13 1224-1400 Sentence denotes Increasing age, lymphocytes, CRP, LDH, D-Dimer, LSS, total abdominal fat as well as VAT were found to have a significant univariate association with the need of intensive care.
T13 1224-1400 Sentence denotes Increasing age, lymphocytes, CRP, LDH, D-Dimer, LSS, total abdominal fat as well as VAT were found to have a significant univariate association with the need of intensive care.
T14 1401-1515 Sentence denotes A multivariate analysis showed that LSS and VAT were independently associated with the need of intensive care (OR:
T14 1401-1515 Sentence denotes A multivariate analysis showed that LSS and VAT were independently associated with the need of intensive care (OR:
T15 1516-1529 Sentence denotes 1.262; 95%CI:
T15 1516-1529 Sentence denotes 1.262; 95%CI:
T16 1530-1560 Sentence denotes 1.0171-1.488; p = .005 and OR:
T16 1530-1560 Sentence denotes 1.0171-1.488; p = .005 and OR:
T17 1561-1574 Sentence denotes 2.474; 95%CI:
T17 1561-1574 Sentence denotes 2.474; 95%CI:
T18 1575-1612 Sentence denotes 1.017-6.019; p = .046, respectively).
T18 1575-1612 Sentence denotes 1.017-6.019; p = .046, respectively).
T19 1613-1695 Sentence denotes CONCLUSIONS: VAT is a marker of worse clinical outcomes in patients with COVID-19.
T19 1613-1695 Sentence denotes CONCLUSIONS: VAT is a marker of worse clinical outcomes in patients with COVID-19.
T20 1696-1852 Sentence denotes Given the exploratory nature of our study, further investigation is needed to confirm our findings and elucidate the mechanisms underlying such association.
T20 1696-1852 Sentence denotes Given the exploratory nature of our study, further investigation is needed to confirm our findings and elucidate the mechanisms underlying such association.