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PubMed:32397174 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern:
T1 0-82 Sentence denotes Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern:
T2 83-139 Sentence denotes The Fragile Balance between Infections and Autoimmunity.
T2 83-139 Sentence denotes The Fragile Balance between Infections and Autoimmunity.
T3 140-353 Sentence denotes On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
T3 140-353 Sentence denotes On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
T4 354-449 Sentence denotes Typical manifestations consist of flu-like symptoms such as fever, cough, fatigue, and dyspnea.
T4 354-449 Sentence denotes Typical manifestations consist of flu-like symptoms such as fever, cough, fatigue, and dyspnea.
T5 450-675 Sentence denotes However, in about 20% of patients, the infection progresses to severe interstitial pneumonia and can induce an uncontrolled host-immune response, leading to a life-threatening condition called cytokine release syndrome (CRS).
T5 450-675 Sentence denotes However, in about 20% of patients, the infection progresses to severe interstitial pneumonia and can induce an uncontrolled host-immune response, leading to a life-threatening condition called cytokine release syndrome (CRS).
T6 676-815 Sentence denotes CRS represents an emergency scenario of a frequent challenge, which is the complex and interwoven link between infections and autoimmunity.
T6 676-815 Sentence denotes CRS represents an emergency scenario of a frequent challenge, which is the complex and interwoven link between infections and autoimmunity.
T7 816-1003 Sentence denotes Indeed, treatment of CRS involves the use of both antivirals to control the underlying infection and immunosuppressive agents to dampen the aberrant pro-inflammatory response of the host.
T7 816-1003 Sentence denotes Indeed, treatment of CRS involves the use of both antivirals to control the underlying infection and immunosuppressive agents to dampen the aberrant pro-inflammatory response of the host.
T8 1004-1212 Sentence denotes Several trials, evaluating the safety and effectiveness of immunosuppressants commonly used in rheumatic diseases, are ongoing in patients with COVID-19 and CRS, some of which are achieving promising results.
T8 1004-1212 Sentence denotes Several trials, evaluating the safety and effectiveness of immunosuppressants commonly used in rheumatic diseases, are ongoing in patients with COVID-19 and CRS, some of which are achieving promising results.
T9 1213-1434 Sentence denotes However, such a use should follow a multidisciplinary approach, be accompanied by close monitoring, be tailored to patient's clinical and serological features, and be initiated at the right time to reach the best results.
T9 1213-1434 Sentence denotes However, such a use should follow a multidisciplinary approach, be accompanied by close monitoring, be tailored to patient's clinical and serological features, and be initiated at the right time to reach the best results.
T10 1435-1659 Sentence denotes Autoimmune patients receiving immunosuppressants could be prone to SARS-CoV-2 infections; however, suspension of the ongoing therapy is contraindicated to avoid disease flares and a consequent increase in the infection risk.
T10 1435-1659 Sentence denotes Autoimmune patients receiving immunosuppressants could be prone to SARS-CoV-2 infections; however, suspension of the ongoing therapy is contraindicated to avoid disease flares and a consequent increase in the infection risk.