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PubMed:32253888 JSONTXT 25 Projects

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Id Subject Object Predicate Lexical cue
T1 0-96 Sentence denotes Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection.
T1 0-96 Sentence denotes Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection.
T2 97-279 Sentence denotes CoV-19/SARS-CoV-2 is a highly pathogenic virus that causes coronavirus-19 disease (COVID-19) an acute respiratory distress syndrome which provokes serious problems for global health.
T2 97-279 Sentence denotes CoV-19/SARS-CoV-2 is a highly pathogenic virus that causes coronavirus-19 disease (COVID-19) an acute respiratory distress syndrome which provokes serious problems for global health.
T3 280-419 Sentence denotes Studies suggest that there are many differences between men and women in the immune response to CoV-19 infection and inflammatory diseases.
T3 280-419 Sentence denotes Studies suggest that there are many differences between men and women in the immune response to CoV-19 infection and inflammatory diseases.
T4 420-579 Sentence denotes Women, compared to men, are less susceptible to viral infections based on a different innate immunity, steroid hormones and factors related to sex chromosomes.
T4 420-579 Sentence denotes Women, compared to men, are less susceptible to viral infections based on a different innate immunity, steroid hormones and factors related to sex chromosomes.
T5 580-675 Sentence denotes The presence of two X chromosomes in women emphasize the immune system even if one is inactive.
T5 580-675 Sentence denotes The presence of two X chromosomes in women emphasize the immune system even if one is inactive.
T6 676-870 Sentence denotes The immune regulatory genes encoded by X chromosome in female gender causes lower viral load levels, and less inflammation than in man, while CD4+ T cells are higher with better immune response.
T6 676-870 Sentence denotes The immune regulatory genes encoded by X chromosome in female gender causes lower viral load levels, and less inflammation than in man, while CD4+ T cells are higher with better immune response.
T7 871-975 Sentence denotes In addition, women generally produce higher levels of antibodies which remain in the circulation longer.
T7 871-975 Sentence denotes In addition, women generally produce higher levels of antibodies which remain in the circulation longer.
T8 976-1126 Sentence denotes The levels of activation of the immune cells are higher in women than in men, and it is correlated with the trigger of TLR7 and the production of IFN.
T8 976-1126 Sentence denotes The levels of activation of the immune cells are higher in women than in men, and it is correlated with the trigger of TLR7 and the production of IFN.
T9 1127-1274 Sentence denotes TLR7 is higher in women than in men and its biallelic expression leads to higher immune responses and increases the resistance to viral infections.
T9 1127-1274 Sentence denotes TLR7 is higher in women than in men and its biallelic expression leads to higher immune responses and increases the resistance to viral infections.
T10 1275-1505 Sentence denotes TLR7 is expressed in innate immune cells which recognizes single strand RNA virus by promoting the production of antibodies against the virus and the generation of pro-inflammatory cytokines including IL-6 and IL-1 family members.
T10 1275-1505 Sentence denotes TLR7 is expressed in innate immune cells which recognizes single strand RNA virus by promoting the production of antibodies against the virus and the generation of pro-inflammatory cytokines including IL-6 and IL-1 family members.
T11 1506-1654 Sentence denotes Moreover, in women the production of inflammatory IL-6 after viral infection is lower than in males and is often correlated with a better longevity.
T11 1506-1654 Sentence denotes Moreover, in women the production of inflammatory IL-6 after viral infection is lower than in males and is often correlated with a better longevity.
T12 1655-1850 Sentence denotes In addition, on the X chromosome there are loci that code for the genes involved in the regulation of immune cells such as FOXP3, and transcription factor for Treg involved in virus pathogenesis.
T12 1655-1850 Sentence denotes In addition, on the X chromosome there are loci that code for the genes involved in the regulation of immune cells such as FOXP3, and transcription factor for Treg involved in virus pathogenesis.
T13 1851-2065 Sentence denotes The X chromosome influences the immune system by acting on many other proteins, including TLR8, CD40L and CXCR3 which can be over-expressed in women, and influence the response to viral infections and vaccinations.
T13 1851-2065 Sentence denotes The X chromosome influences the immune system by acting on many other proteins, including TLR8, CD40L and CXCR3 which can be over-expressed in women, and influence the response to viral infections and vaccinations.
T14 2066-2180 Sentence denotes However, the biallelic expression of the X-linked genes can promote harmful autoimmune and inflammatory responses.
T14 2066-2180 Sentence denotes However, the biallelic expression of the X-linked genes can promote harmful autoimmune and inflammatory responses.
T15 2181-2365 Sentence denotes Cardiovascular diseases are more frequent in males and subjects without cardiovascular dysfunctions infected by CoV-19 have a better prognosis, but these effects are still under study.
T15 2181-2365 Sentence denotes Cardiovascular diseases are more frequent in males and subjects without cardiovascular dysfunctions infected by CoV-19 have a better prognosis, but these effects are still under study.
T16 2366-2744 Sentence denotes It is hoped that certain drugs, such as CoV-19 receptor blockers, anti-inflammatories (against rheumatic diseases), monoclonal antibodies, anti-IL-1 and anti-IL-6, the remdesevir drug (analogue adenosine, effective against ebola), hydroxychloroquine (for the treatment of malaria) and vaccines, will open up new strategies and new therapeutic ways to combat this terrible virus.
T16 2366-2744 Sentence denotes It is hoped that certain drugs, such as CoV-19 receptor blockers, anti-inflammatories (against rheumatic diseases), monoclonal antibodies, anti-IL-1 and anti-IL-6, the remdesevir drug (analogue adenosine, effective against ebola), hydroxychloroquine (for the treatment of malaria) and vaccines, will open up new strategies and new therapeutic ways to combat this terrible virus.