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PubMed:32118639 JSONTXT 18 Projects

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Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients.
T1 0-97 Sentence denotes Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients.
T2 98-109 Sentence denotes BACKGROUND:
T2 98-109 Sentence denotes BACKGROUND:
T3 110-227 Sentence denotes A patient's infectivity is determined by the presence of the virus in different body fluids, secretions, and excreta.
T3 110-227 Sentence denotes A patient's infectivity is determined by the presence of the virus in different body fluids, secretions, and excreta.
T4 228-370 Sentence denotes The persistence and clearance of viral RNA from different specimens of patients with 2019 novel coronavirus disease (COVID-19) remain unclear.
T4 228-370 Sentence denotes The persistence and clearance of viral RNA from different specimens of patients with 2019 novel coronavirus disease (COVID-19) remain unclear.
T5 371-609 Sentence denotes This study analyzed the clearance time and factors influencing 2019 novel coronavirus (2019-nCoV) RNA in different samples from patients with COVID-19, providing further evidence to improve the management of patients during convalescence.
T5 371-609 Sentence denotes This study analyzed the clearance time and factors influencing 2019 novel coronavirus (2019-nCoV) RNA in different samples from patients with COVID-19, providing further evidence to improve the management of patients during convalescence.
T6 610-618 Sentence denotes METHODS:
T6 610-618 Sentence denotes METHODS:
T7 619-799 Sentence denotes The clinical data and laboratory test results of convalescent patients with COVID-19 who were admitted to from January 20, 2020 to February 10, 2020 were collected retrospectively.
T7 619-799 Sentence denotes The clinical data and laboratory test results of convalescent patients with COVID-19 who were admitted to from January 20, 2020 to February 10, 2020 were collected retrospectively.
T8 800-963 Sentence denotes The reverse transcription polymerase chain reaction (RT-PCR) results for patients' oropharyngeal swab, stool, urine, and serum samples were collected and analyzed.
T8 800-963 Sentence denotes The reverse transcription polymerase chain reaction (RT-PCR) results for patients' oropharyngeal swab, stool, urine, and serum samples were collected and analyzed.
T9 964-1174 Sentence denotes Convalescent patients refer to recovered non-febrile patients without respiratory symptoms who had two successive (minimum 24 h sampling interval) negative RT-PCR results for viral RNA from oropharyngeal swabs.
T9 964-1174 Sentence denotes Convalescent patients refer to recovered non-febrile patients without respiratory symptoms who had two successive (minimum 24 h sampling interval) negative RT-PCR results for viral RNA from oropharyngeal swabs.
T10 1175-1341 Sentence denotes The effects of cluster of differentiation 4 (CD4)+ T lymphocytes, inflammatory indicators, and glucocorticoid treatment on viral nucleic acid clearance were analyzed.
T10 1175-1341 Sentence denotes The effects of cluster of differentiation 4 (CD4)+ T lymphocytes, inflammatory indicators, and glucocorticoid treatment on viral nucleic acid clearance were analyzed.
T11 1342-1350 Sentence denotes RESULTS:
T11 1342-1350 Sentence denotes RESULTS:
T12 1351-1448 Sentence denotes In the 292 confirmed cases, 66 patients recovered after treatment and were included in our study.
T12 1351-1448 Sentence denotes In the 292 confirmed cases, 66 patients recovered after treatment and were included in our study.
T13 1449-1553 Sentence denotes In total, 28 (42.4%) women and 38 men (57.6%) with a median age of 44.0 (34.0-62.0) years were analyzed.
T13 1449-1553 Sentence denotes In total, 28 (42.4%) women and 38 men (57.6%) with a median age of 44.0 (34.0-62.0) years were analyzed.
T14 1554-1660 Sentence denotes After in-hospital treatment, patients' inflammatory indicators decreased with improved clinical condition.
T14 1554-1660 Sentence denotes After in-hospital treatment, patients' inflammatory indicators decreased with improved clinical condition.
T15 1661-1810 Sentence denotes The median time from the onset of symptoms to first negative RT-PCR results for oropharyngeal swabs in convalescent patients was 9.5 (6.0-11.0) days.
T15 1661-1810 Sentence denotes The median time from the onset of symptoms to first negative RT-PCR results for oropharyngeal swabs in convalescent patients was 9.5 (6.0-11.0) days.
T16 1811-2066 Sentence denotes By February 10, 2020, 11 convalescent patients (16.7%) still tested positive for viral RNA from stool specimens and the other 55 patients' stool specimens were negative for 2019-nCoV following a median duration of 11.0 (9.0-16.0) days after symptom onset.
T16 1811-2066 Sentence denotes By February 10, 2020, 11 convalescent patients (16.7%) still tested positive for viral RNA from stool specimens and the other 55 patients' stool specimens were negative for 2019-nCoV following a median duration of 11.0 (9.0-16.0) days after symptom onset.
T17 2067-2232 Sentence denotes Among these 55 patients, 43 had a longer duration until stool specimens were negative for viral RNA than for throat swabs, with a median delay of 2.0 (1.0-4.0) days.
T17 2067-2232 Sentence denotes Among these 55 patients, 43 had a longer duration until stool specimens were negative for viral RNA than for throat swabs, with a median delay of 2.0 (1.0-4.0) days.
T18 2233-2426 Sentence denotes Results for only four (6.9%) urine samples were positive for viral nucleic acid out of 58 cases; viral RNA was still present in three patients' urine specimens after throat swabs were negative.
T18 2233-2426 Sentence denotes Results for only four (6.9%) urine samples were positive for viral nucleic acid out of 58 cases; viral RNA was still present in three patients' urine specimens after throat swabs were negative.
T19 2427-2666 Sentence denotes Using a multiple linear regression model (F = 2.669, P = 0.044, and adjusted R = 0.122), the analysis showed that the CD4+ T lymphocyte count may help predict the duration of viral RNA detection in patients' stools (t = -2.699, P = 0.010).
T19 2427-2666 Sentence denotes Using a multiple linear regression model (F = 2.669, P = 0.044, and adjusted R = 0.122), the analysis showed that the CD4+ T lymphocyte count may help predict the duration of viral RNA detection in patients' stools (t = -2.699, P = 0.010).
T20 2667-3122 Sentence denotes The duration of viral RNA detection from oropharyngeal swabs and fecal samples in the glucocorticoid treatment group was longer than that in the non-glucocorticoid treatment group (15 days vs. 8.0 days, respectively; t = 2.550, P = 0.013) and the duration of viral RNA detection in fecal samples in the glucocorticoid treatment group was longer than that in the non-glucocorticoid treatment group (20 days vs. 11 days, respectively; t = 4.631, P < 0.001).
T20 2667-3122 Sentence denotes The duration of viral RNA detection from oropharyngeal swabs and fecal samples in the glucocorticoid treatment group was longer than that in the non-glucocorticoid treatment group (15 days vs. 8.0 days, respectively; t = 2.550, P = 0.013) and the duration of viral RNA detection in fecal samples in the glucocorticoid treatment group was longer than that in the non-glucocorticoid treatment group (20 days vs. 11 days, respectively; t = 4.631, P < 0.001).
T21 3123-3303 Sentence denotes There was no statistically significant difference in inflammatory indicators between patients with positive fecal viral RNA test results and those with negative results (P > 0.05).
T21 3123-3303 Sentence denotes There was no statistically significant difference in inflammatory indicators between patients with positive fecal viral RNA test results and those with negative results (P > 0.05).
T22 3304-3316 Sentence denotes CONCLUSIONS:
T22 3304-3316 Sentence denotes CONCLUSIONS:
T23 3317-3498 Sentence denotes In brief, as the clearance of viral RNA in patients' stools was delayed compared to that in oropharyngeal swabs, it is important to identify viral RNA in feces during convalescence.
T23 3317-3498 Sentence denotes In brief, as the clearance of viral RNA in patients' stools was delayed compared to that in oropharyngeal swabs, it is important to identify viral RNA in feces during convalescence.
T24 3499-3678 Sentence denotes Because of the delayed clearance of viral RNA in the glucocorticoid treatment group, glucocorticoids are not recommended in the treatment of COVID-19, especially for mild disease.
T24 3499-3678 Sentence denotes Because of the delayed clearance of viral RNA in the glucocorticoid treatment group, glucocorticoids are not recommended in the treatment of COVID-19, especially for mild disease.
T25 3679-3742 Sentence denotes The duration of RNA detection may relate to host cell immunity.
T25 3679-3742 Sentence denotes The duration of RNA detection may relate to host cell immunity.