> top > projects > Inflammaging > docs > PubMed:31655933 > annotations
Inflammaging  

PubMed:31655933 JSONTXT 2 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-115 Sentence denotes Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus.
T1 0-115 Sentence denotes Increased sMer, but not sAxl, sTyro3, and Gas6 relate with active disease in juvenile systemic lupus erythematosus.
T2 116-140 Sentence denotes INTRODUCTION/OBJECTIVES:
T2 116-140 Sentence denotes INTRODUCTION/OBJECTIVES:
T3 141-322 Sentence denotes Tyro3, Axl, and Mer (TAM) receptors and ligands mediate apoptotic bodies engulfment which alteration has been related with juvenile systemic lupus erythematosus (JSLE) pathogenesis.
T3 141-322 Sentence denotes Tyro3, Axl, and Mer (TAM) receptors and ligands mediate apoptotic bodies engulfment which alteration has been related with juvenile systemic lupus erythematosus (JSLE) pathogenesis.
T4 323-375 Sentence denotes Thus, the aim was to determine their soluble levels.
T4 323-375 Sentence denotes Thus, the aim was to determine their soluble levels.
T5 376-384 Sentence denotes METHODS:
T5 376-384 Sentence denotes METHODS:
T6 385-644 Sentence denotes Serum sTyro3, sAxl, sMer, and Gas6 levels were measured using ELISA in 67 JSLE patients, 12 juvenile idiopathic arthritis (JIA) inflammatory and 20 healthy controls and related with SLEDAI-2K score, anti-dsDNA antibody, ESR, CRP, C3, C4 levels, and nephritis.
T6 385-644 Sentence denotes Serum sTyro3, sAxl, sMer, and Gas6 levels were measured using ELISA in 67 JSLE patients, 12 juvenile idiopathic arthritis (JIA) inflammatory and 20 healthy controls and related with SLEDAI-2K score, anti-dsDNA antibody, ESR, CRP, C3, C4 levels, and nephritis.
T7 645-1054 Sentence denotes RESULTS: JSLE patients with active disease (SLEDAI-2K> 4) had significantly increased sMer levels compared with healthy controls (median 8.4 vs. 6.0 ng/mL, p = 0.009) and inactive disease patients (5.2 ng/mL, p = 0.0003). sMer levels correlated with SLEDAI-2K (r = 0.44; p = 0.0004) and ESR (r = 0.24; p = 0.04), while sAxl correlated with SLEDAI-2K (r = 0.33; p = 0.008) and C4 levels (r = - 0.24; p = 0.04).
T7 645-1054 Sentence denotes RESULTS: JSLE patients with active disease (SLEDAI-2K> 4) had significantly increased sMer levels compared with healthy controls (median 8.4 vs. 6.0 ng/mL, p = 0.009) and inactive disease patients (5.2 ng/mL, p = 0.0003). sMer levels correlated with SLEDAI-2K (r = 0.44; p = 0.0004) and ESR (r = 0.24; p = 0.04), while sAxl correlated with SLEDAI-2K (r = 0.33; p = 0.008) and C4 levels (r = - 0.24; p = 0.04).
T8 1055-1126 Sentence denotes JSLE patients taking glucocorticoid had increased sAxl and sMer levels.
T8 1055-1126 Sentence denotes JSLE patients taking glucocorticoid had increased sAxl and sMer levels.
T9 1127-1181 Sentence denotes Moreover, sAxl correlated with sMer and sTyro3 levels.
T9 1127-1181 Sentence denotes Moreover, sAxl correlated with sMer and sTyro3 levels.
T10 1182-1522 Sentence denotes Patients with nephritis and those with focal or diffuse proliferative glomerulonephritis had these protein levels similar to healthy controls and patients without renal involvement. sTyro3 levels of JSLE patients taking glucocorticoid were decreased, and correlated with Gas6 and sAxl, while Gas6 levels correlated with age upon enrollment.
T10 1182-1522 Sentence denotes Patients with nephritis and those with focal or diffuse proliferative glomerulonephritis had these protein levels similar to healthy controls and patients without renal involvement. sTyro3 levels of JSLE patients taking glucocorticoid were decreased, and correlated with Gas6 and sAxl, while Gas6 levels correlated with age upon enrollment.
T11 1523-1601 Sentence denotes JIA controls had protein levels similar to healthy controls and JSLE patients.
T11 1523-1601 Sentence denotes JIA controls had protein levels similar to healthy controls and JSLE patients.
T12 1602-1614 Sentence denotes CONCLUSIONS:
T12 1602-1614 Sentence denotes CONCLUSIONS:
T13 1615-1791 Sentence denotes This study reinforces that sMer is increased in active JSLE patients, yet sMer and sAxl correlates with disease activity parameters, and their alterations are disease-specific.
T13 1615-1791 Sentence denotes This study reinforces that sMer is increased in active JSLE patients, yet sMer and sAxl correlates with disease activity parameters, and their alterations are disease-specific.
T14 1792-1896 Sentence denotes However, further studies are needed to determine exact roles of sTyro3 and Gas6 in disease pathogenesis.
T14 1792-1896 Sentence denotes However, further studies are needed to determine exact roles of sTyro3 and Gas6 in disease pathogenesis.
T15 1897-2207 Sentence denotes Key Points • sMer and sAxl serum levels are related with active disease in JSLE patients • sMer correlated with SLEDAI-2K score in JSLE • sTyro3, sAxl, sMer and Gas6 levels did not related with nephritis in JSLE patients • sTyro3 and Gas6 exact roles in JSLE are not established and further studies are needed.
T15 1897-2207 Sentence denotes Key Points • sMer and sAxl serum levels are related with active disease in JSLE patients • sMer correlated with SLEDAI-2K score in JSLE • sTyro3, sAxl, sMer and Gas6 levels did not related with nephritis in JSLE patients • sTyro3 and Gas6 exact roles in JSLE are not established and further studies are needed.