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PubMed:29777476 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T1 0-164 Sentence denotes Comparison of procalcitonin, a potentially new inflammatory biomarker of frailty, to interleukin-6 and C-reactive protein among older Chinese hospitalized patients.
T1 0-164 Sentence denotes Comparison of procalcitonin, a potentially new inflammatory biomarker of frailty, to interleukin-6 and C-reactive protein among older Chinese hospitalized patients.
T2 165-169 Sentence denotes AIM:
T2 165-169 Sentence denotes AIM:
T3 170-286 Sentence denotes Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty.
T3 170-286 Sentence denotes Procalcitonin (PCT) has predictive value for patients with infectious diseases, but has not been studied in frailty.
T4 287-489 Sentence denotes The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients.
T4 287-489 Sentence denotes The purpose of this study was to compare PCT to two other inflammatory biomarkers [interleukin-6 (IL-6)] and C-reactive protein (CRP) in their association with frailty among older hospitalized patients.
T5 490-498 Sentence denotes METHODS:
T5 490-498 Sentence denotes METHODS:
T6 499-619 Sentence denotes Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission.
T6 499-619 Sentence denotes Retrospective study of inpatients (June-December, 2016), who had all three biomarkers measured within 24 h of admission.
T7 620-702 Sentence denotes Frailty was defined according to the Chinese version of a validated frailty scale.
T7 620-702 Sentence denotes Frailty was defined according to the Chinese version of a validated frailty scale.
T8 703-880 Sentence denotes Due to the association of biomarkers with infection, we divided patients into "non-infected" (no pneumonia or other infections) and "pneumonia" (using standard criteria) groups.
T8 703-880 Sentence denotes Due to the association of biomarkers with infection, we divided patients into "non-infected" (no pneumonia or other infections) and "pneumonia" (using standard criteria) groups.
T9 881-889 Sentence denotes RESULTS:
T9 881-889 Sentence denotes RESULTS:
T10 890-1022 Sentence denotes Of 435 patients (mean age 81.6 ± 8.6 years), 181 (41.6%) were designated the non-infected group and 254 (58.4%) the pneumonia group.
T10 890-1022 Sentence denotes Of 435 patients (mean age 81.6 ± 8.6 years), 181 (41.6%) were designated the non-infected group and 254 (58.4%) the pneumonia group.
T11 1023-1183 Sentence denotes Prevalence of frailty in the non-infected group was 32.0% (58/181) and frailty (univariate analysis) was associated with higher PCT and IL-6 levels but not CRP.
T11 1023-1183 Sentence denotes Prevalence of frailty in the non-infected group was 32.0% (58/181) and frailty (univariate analysis) was associated with higher PCT and IL-6 levels but not CRP.
T12 1184-1302 Sentence denotes Prevalence of frailty in the pneumonia group was 40.2% (102/254) and frailty was associated with all three biomarkers.
T12 1184-1302 Sentence denotes Prevalence of frailty in the pneumonia group was 40.2% (102/254) and frailty was associated with all three biomarkers.
T13 1303-1629 Sentence denotes In multivariable analysis adjusting for age, gender, smoking, alcohol use, hemoglobin, albumin, neutrophils and creatinine, PCT (not IL-6 and CRP) was associated with frailty in the non-infected group (OR = 5.244; 95% CI, 1.622-16.947; P = 0.006) and none of the biomarkers were associated with frailty in the pneumonia group.
T13 1303-1629 Sentence denotes In multivariable analysis adjusting for age, gender, smoking, alcohol use, hemoglobin, albumin, neutrophils and creatinine, PCT (not IL-6 and CRP) was associated with frailty in the non-infected group (OR = 5.244; 95% CI, 1.622-16.947; P = 0.006) and none of the biomarkers were associated with frailty in the pneumonia group.
T14 1630-1642 Sentence denotes CONCLUSIONS:
T14 1630-1642 Sentence denotes CONCLUSIONS:
T15 1643-1801 Sentence denotes Although the study is limited due to the retrospective methods, PCT but not IL-6 or CRP, was associated with frailty among older inpatients without infection.
T15 1643-1801 Sentence denotes Although the study is limited due to the retrospective methods, PCT but not IL-6 or CRP, was associated with frailty among older inpatients without infection.
T16 1802-1886 Sentence denotes None of these biomarkers were associated with frailty among patients with pneumonia.
T16 1802-1886 Sentence denotes None of these biomarkers were associated with frailty among patients with pneumonia.