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Id Subject Object Predicate Lexical cue
T1 0-91 Sentence denotes Fluid resuscitation with lactated Ringer's solution vs normal saline in acute pancreatitis:
T1 0-91 Sentence denotes Fluid resuscitation with lactated Ringer's solution vs normal saline in acute pancreatitis:
T2 92-137 Sentence denotes A triple-blind, randomized, controlled trial.
T2 92-137 Sentence denotes A triple-blind, randomized, controlled trial.
T3 138-149 Sentence denotes BACKGROUND:
T3 138-149 Sentence denotes BACKGROUND:
T4 150-243 Sentence denotes Little is known regarding the optimal type of fluid resuscitation in acute pancreatitis (AP).
T4 150-243 Sentence denotes Little is known regarding the optimal type of fluid resuscitation in acute pancreatitis (AP).
T5 244-254 Sentence denotes OBJECTIVE:
T5 244-254 Sentence denotes OBJECTIVE:
T6 255-403 Sentence denotes The objective of this article was to compare the effect of lactated Ringer's solution (LR) vs normal saline (NS) in the inflammatory response in AP.
T6 255-403 Sentence denotes The objective of this article was to compare the effect of lactated Ringer's solution (LR) vs normal saline (NS) in the inflammatory response in AP.
T7 404-412 Sentence denotes METHODS:
T7 404-412 Sentence denotes METHODS:
T8 413-471 Sentence denotes We conducted a triple-blind, randomized, controlled trial.
T8 413-471 Sentence denotes We conducted a triple-blind, randomized, controlled trial.
T9 472-517 Sentence denotes Patients ≥ 18 admitted with AP were eligible.
T9 472-517 Sentence denotes Patients ≥ 18 admitted with AP were eligible.
T10 518-563 Sentence denotes Patients were randomized to receive LR or NS.
T10 518-563 Sentence denotes Patients were randomized to receive LR or NS.
T11 564-763 Sentence denotes Primary outcome variables were number of systemic inflammatory response syndrome (SIRS) criteria at 24 hours, 48 hours and 72 hours and blood C-reactive protein (CRP) levels at 48 hours and 72 hours.
T11 564-763 Sentence denotes Primary outcome variables were number of systemic inflammatory response syndrome (SIRS) criteria at 24 hours, 48 hours and 72 hours and blood C-reactive protein (CRP) levels at 48 hours and 72 hours.
T12 764-886 Sentence denotes In vitro complementary experiments were performed to further explore the interaction between pH, lactate and inflammation.
T12 764-886 Sentence denotes In vitro complementary experiments were performed to further explore the interaction between pH, lactate and inflammation.
T13 887-895 Sentence denotes RESULTS:
T13 887-895 Sentence denotes RESULTS:
T14 896-961 Sentence denotes Nineteen patients receiving LR and 21 receiving NS were analyzed.
T14 896-961 Sentence denotes Nineteen patients receiving LR and 21 receiving NS were analyzed.
T15 962-1068 Sentence denotes The median (p25-p75) number of SIRS criteria at 48 hours were 1 (1-2) for NS vs 1 (0-1) for LR, p = 0.060.
T15 962-1068 Sentence denotes The median (p25-p75) number of SIRS criteria at 48 hours were 1 (1-2) for NS vs 1 (0-1) for LR, p = 0.060.
T16 1069-1217 Sentence denotes CRP levels (mg/l) were as follows: at 48 hours NS 166 (78-281) vs LR 28 (3-124), p = 0.037; at 72 hours NS 217 (59-323) vs LR 25 (3-169), p = 0.043.
T16 1069-1217 Sentence denotes CRP levels (mg/l) were as follows: at 48 hours NS 166 (78-281) vs LR 28 (3-124), p = 0.037; at 72 hours NS 217 (59-323) vs LR 25 (3-169), p = 0.043.
T17 1218-1317 Sentence denotes In vitro, LR inhibited the induction of inflammatory phenotype of macrophages and NF-κB activation.
T17 1218-1317 Sentence denotes In vitro, LR inhibited the induction of inflammatory phenotype of macrophages and NF-κB activation.
T18 1318-1449 Sentence denotes This effect was not observed when using Ringer's solution without lactate, suggesting a direct anti-inflammatory effect of lactate.
T18 1318-1449 Sentence denotes This effect was not observed when using Ringer's solution without lactate, suggesting a direct anti-inflammatory effect of lactate.
T19 1450-1462 Sentence denotes CONCLUSIONS:
T19 1450-1462 Sentence denotes CONCLUSIONS:
T20 1463-1564 Sentence denotes Lactated Ringer's is associated with an anti-inflammatory effect in patients with acute pancreatitis.
T20 1463-1564 Sentence denotes Lactated Ringer's is associated with an anti-inflammatory effect in patients with acute pancreatitis.