| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-118 |
Sentence |
denotes |
Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers. |
| T1 |
0-118 |
Sentence |
denotes |
Ileal pouch of ulcerative colitis and familial adenomatous polyposis patients exhibit modulation of autophagy markers. |
| T2 |
119-289 |
Sentence |
denotes |
Total retocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgery of choice for patients with ulcerative colitis (UC) that are refractory to clinical treatment. |
| T2 |
119-289 |
Sentence |
denotes |
Total retocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgery of choice for patients with ulcerative colitis (UC) that are refractory to clinical treatment. |
| T3 |
290-361 |
Sentence |
denotes |
Pouchitis is one of the most common complications after this procedure. |
| T3 |
290-361 |
Sentence |
denotes |
Pouchitis is one of the most common complications after this procedure. |
| T4 |
362-433 |
Sentence |
denotes |
Defects in autophagy have been reported in inflammatory bowel diseases. |
| T4 |
362-433 |
Sentence |
denotes |
Defects in autophagy have been reported in inflammatory bowel diseases. |
| T5 |
434-474 |
Sentence |
denotes |
However, there are no studies on the IP. |
| T5 |
434-474 |
Sentence |
denotes |
However, there are no studies on the IP. |
| T6 |
475-613 |
Sentence |
denotes |
Therefore, we studied markers for autophagy in the IP mucosa of UC and FAP patients comparing them to controls with a normal distal ileum. |
| T6 |
475-613 |
Sentence |
denotes |
Therefore, we studied markers for autophagy in the IP mucosa of UC and FAP patients comparing them to controls with a normal distal ileum. |
| T7 |
614-715 |
Sentence |
denotes |
Sixteen patients with IP in "J" shape, asymptomatic and with endoscopically normal IP were evaluated. |
| T7 |
614-715 |
Sentence |
denotes |
Sixteen patients with IP in "J" shape, asymptomatic and with endoscopically normal IP were evaluated. |
| T8 |
716-786 |
Sentence |
denotes |
The control group consisted of eight patients with normal colonoscopy. |
| T8 |
716-786 |
Sentence |
denotes |
The control group consisted of eight patients with normal colonoscopy. |
| T9 |
787-893 |
Sentence |
denotes |
There was a significant decrease in the transcriptional levels of ATG5, MAP1LC3A and BAX in the FAP group. |
| T9 |
787-893 |
Sentence |
denotes |
There was a significant decrease in the transcriptional levels of ATG5, MAP1LC3A and BAX in the FAP group. |
| T10 |
894-1001 |
Sentence |
denotes |
There was also a decrease in the protein level of Beclin-1 in the UC and FAP compared to the control group. |
| T10 |
894-1001 |
Sentence |
denotes |
There was also a decrease in the protein level of Beclin-1 in the UC and FAP compared to the control group. |
| T11 |
1002-1189 |
Sentence |
denotes |
Although the LC3II levels by immunoblot were higher in the UC group, LC3/p62 co-localization were lower in the immunofluorescence analysis in the UC and FAP compared to the control group. |
| T11 |
1002-1189 |
Sentence |
denotes |
Although the LC3II levels by immunoblot were higher in the UC group, LC3/p62 co-localization were lower in the immunofluorescence analysis in the UC and FAP compared to the control group. |
| T12 |
1190-1278 |
Sentence |
denotes |
Corroborating these results, there was an increase of p62 by immunoblot in the UC group. |
| T12 |
1190-1278 |
Sentence |
denotes |
Corroborating these results, there was an increase of p62 by immunoblot in the UC group. |
| T13 |
1279-1411 |
Sentence |
denotes |
These findings indicated a modulation of macroautophagy markers in the IP, which may explain the mucosa inflammation predisposition. |
| T13 |
1279-1411 |
Sentence |
denotes |
These findings indicated a modulation of macroautophagy markers in the IP, which may explain the mucosa inflammation predisposition. |