| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-165 |
Sentence |
denotes |
The prevalence of irritable bowel syndrome-type symptoms in paediatric inflammatory bowel disease, and the relationship with biochemical markers of disease activity. |
| T1 |
0-165 |
Sentence |
denotes |
The prevalence of irritable bowel syndrome-type symptoms in paediatric inflammatory bowel disease, and the relationship with biochemical markers of disease activity. |
| T2 |
166-177 |
Sentence |
denotes |
BACKGROUND: |
| T2 |
166-177 |
Sentence |
denotes |
BACKGROUND: |
| T3 |
178-359 |
Sentence |
denotes |
A large proportion (25-46%) of adults with inflammatory bowel disease in remission has symptoms of irritable bowel syndrome (IBS), which are thought to reflect ongoing inflammation. |
| T3 |
178-359 |
Sentence |
denotes |
A large proportion (25-46%) of adults with inflammatory bowel disease in remission has symptoms of irritable bowel syndrome (IBS), which are thought to reflect ongoing inflammation. |
| T4 |
360-427 |
Sentence |
denotes |
Data on paediatric inflammatory bowel disease patients are lacking. |
| T4 |
360-427 |
Sentence |
denotes |
Data on paediatric inflammatory bowel disease patients are lacking. |
| T5 |
428-432 |
Sentence |
denotes |
AIM: |
| T5 |
428-432 |
Sentence |
denotes |
AIM: |
| T6 |
433-643 |
Sentence |
denotes |
To investigate (i) the prevalence of IBS-type symptoms in paediatric inflammatory bowel disease patients in remission and (ii) the relationship of IBS-type symptoms with biochemical markers of disease activity. |
| T6 |
433-643 |
Sentence |
denotes |
To investigate (i) the prevalence of IBS-type symptoms in paediatric inflammatory bowel disease patients in remission and (ii) the relationship of IBS-type symptoms with biochemical markers of disease activity. |
| T7 |
644-652 |
Sentence |
denotes |
METHODS: |
| T7 |
644-652 |
Sentence |
denotes |
METHODS: |
| T8 |
653-855 |
Sentence |
denotes |
This cross-sectional study included all patients (<18 years) with Crohn's disease or ulcerative colitis attending the out-patient clinic of one of three Dutch hospitals between March 2014 and June 2015. |
| T8 |
653-855 |
Sentence |
denotes |
This cross-sectional study included all patients (<18 years) with Crohn's disease or ulcerative colitis attending the out-patient clinic of one of three Dutch hospitals between March 2014 and June 2015. |
| T9 |
856-934 |
Sentence |
denotes |
Clinical disease activity was determined using the abbreviated-PCDAI or PUCAI. |
| T9 |
856-934 |
Sentence |
denotes |
Clinical disease activity was determined using the abbreviated-PCDAI or PUCAI. |
| T10 |
935-1017 |
Sentence |
denotes |
Biochemical disease activity was assessed using faecal calprotectin and serum CRP. |
| T10 |
935-1017 |
Sentence |
denotes |
Biochemical disease activity was assessed using faecal calprotectin and serum CRP. |
| T11 |
1018-1098 |
Sentence |
denotes |
IBS-symptoms were assessed using physician-administered Rome III-questionnaires. |
| T11 |
1018-1098 |
Sentence |
denotes |
IBS-symptoms were assessed using physician-administered Rome III-questionnaires. |
| T12 |
1099-1107 |
Sentence |
denotes |
RESULTS: |
| T12 |
1099-1107 |
Sentence |
denotes |
RESULTS: |
| T13 |
1108-1154 |
Sentence |
denotes |
We included 184 patients (92 female; mean age: |
| T13 |
1108-1154 |
Sentence |
denotes |
We included 184 patients (92 female; mean age: |
| T14 |
1155-1184 |
Sentence |
denotes |
14.5 years) (Crohn's disease: |
| T14 |
1155-1184 |
Sentence |
denotes |
14.5 years) (Crohn's disease: |
| T15 |
1185-1209 |
Sentence |
denotes |
123, ulcerative colitis: |
| T15 |
1185-1209 |
Sentence |
denotes |
123, ulcerative colitis: |
| T16 |
1210-1214 |
Sentence |
denotes |
61). |
| T16 |
1210-1214 |
Sentence |
denotes |
61). |
| T17 |
1215-1334 |
Sentence |
denotes |
The prevalence of IBS-type symptoms in children with inflammatory bowel disease in clinical remission was 6.4% (95% CI: |
| T17 |
1215-1334 |
Sentence |
denotes |
The prevalence of IBS-type symptoms in children with inflammatory bowel disease in clinical remission was 6.4% (95% CI: |
| T18 |
1335-1362 |
Sentence |
denotes |
2.5-11.1%; Crohn's disease: |
| T18 |
1335-1362 |
Sentence |
denotes |
2.5-11.1%; Crohn's disease: |
| T19 |
1363-1388 |
Sentence |
denotes |
4.5%; ulcerative colitis: |
| T19 |
1363-1388 |
Sentence |
denotes |
4.5%; ulcerative colitis: |
| T20 |
1389-1396 |
Sentence |
denotes |
10.8%). |
| T20 |
1389-1396 |
Sentence |
denotes |
10.8%). |
| T21 |
1397-1494 |
Sentence |
denotes |
Prevalence of IBS-type symptoms in children with faecal calprotectin <250 μg/g was 16.1% (95% CI: |
| T21 |
1397-1494 |
Sentence |
denotes |
Prevalence of IBS-type symptoms in children with faecal calprotectin <250 μg/g was 16.1% (95% CI: |
| T22 |
1495-1522 |
Sentence |
denotes |
7.6-25.8%; Crohn's disease: |
| T22 |
1495-1522 |
Sentence |
denotes |
7.6-25.8%; Crohn's disease: |
| T23 |
1523-1549 |
Sentence |
denotes |
16.7%; ulcerative colitis: |
| T23 |
1523-1549 |
Sentence |
denotes |
16.7%; ulcerative colitis: |
| T24 |
1550-1557 |
Sentence |
denotes |
10.8%). |
| T24 |
1550-1557 |
Sentence |
denotes |
10.8%). |
| T25 |
1558-1805 |
Sentence |
denotes |
No difference in faecal calprotectin or CRP was found between patients in clinical remission with or without IBS-type symptoms (faecal calprotectin: IBS+ median 58 μg/g, IBS- 221 μg/g, P = 0.12; CRP: IBS+ median 1.4 mg/L, IBS- 1.1 mg/L, P = 0.63). |
| T25 |
1558-1805 |
Sentence |
denotes |
No difference in faecal calprotectin or CRP was found between patients in clinical remission with or without IBS-type symptoms (faecal calprotectin: IBS+ median 58 μg/g, IBS- 221 μg/g, P = 0.12; CRP: IBS+ median 1.4 mg/L, IBS- 1.1 mg/L, P = 0.63). |
| T26 |
1806-1818 |
Sentence |
denotes |
CONCLUSIONS: |
| T26 |
1806-1818 |
Sentence |
denotes |
CONCLUSIONS: |
| T27 |
1819-1950 |
Sentence |
denotes |
The prevalence of IBS-type symptoms in children with inflammatory bowel disease is highly dependent on the definition of remission. |
| T27 |
1819-1950 |
Sentence |
denotes |
The prevalence of IBS-type symptoms in children with inflammatory bowel disease is highly dependent on the definition of remission. |
| T28 |
1951-2079 |
Sentence |
denotes |
Nonetheless, the prevalence is much lower than that previously reported in studies in adult inflammatory bowel disease patients. |
| T28 |
1951-2079 |
Sentence |
denotes |
Nonetheless, the prevalence is much lower than that previously reported in studies in adult inflammatory bowel disease patients. |
| T29 |
2080-2154 |
Sentence |
denotes |
IBS-type symptoms appear to be unrelated to gastrointestinal inflammation. |
| T29 |
2080-2154 |
Sentence |
denotes |
IBS-type symptoms appear to be unrelated to gastrointestinal inflammation. |