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PubMed:22868358 JSONTXT 9 Projects

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Id Subject Object Predicate Lexical cue
T1 0-164 Sentence denotes Posthepatectomy HBV reactivation in hepatitis B-related hepatocellular carcinoma influences postoperative survival in patients with preoperative low HBV-DNA levels.
T1 0-164 Sentence denotes Posthepatectomy HBV reactivation in hepatitis B-related hepatocellular carcinoma influences postoperative survival in patients with preoperative low HBV-DNA levels.
T2 165-175 Sentence denotes OBJECTIVE:
T2 165-175 Sentence denotes OBJECTIVE:
T3 176-451 Sentence denotes This study aimed to clarify the incidence of hepatitis B virus (HBV) reactivation and its significance on long-term survival after partial hepatectomy in patients with HBV-related hepatocellular carcinoma (HCC), who had preoperative low HBV-DNA level of less than 2000 IU/mL.
T3 176-451 Sentence denotes This study aimed to clarify the incidence of hepatitis B virus (HBV) reactivation and its significance on long-term survival after partial hepatectomy in patients with HBV-related hepatocellular carcinoma (HCC), who had preoperative low HBV-DNA level of less than 2000 IU/mL.
T4 452-582 Sentence denotes BACKGROUND: HBV reactivation is a frequent complication of systemic chemotherapy in hepatitis B surface antigen-positive patients.
T4 452-582 Sentence denotes BACKGROUND: HBV reactivation is a frequent complication of systemic chemotherapy in hepatitis B surface antigen-positive patients.
T5 583-695 Sentence denotes Surgery and anesthesia result in a generalized state of immunosuppression in the immediate postoperative period.
T5 583-695 Sentence denotes Surgery and anesthesia result in a generalized state of immunosuppression in the immediate postoperative period.
T6 696-780 Sentence denotes Data on HBV reactivation and its significance after partial hepatectomy are unclear.
T6 696-780 Sentence denotes Data on HBV reactivation and its significance after partial hepatectomy are unclear.
T7 781-802 Sentence denotes PATIENTS AND METHODS:
T7 781-802 Sentence denotes PATIENTS AND METHODS:
T8 803-888 Sentence denotes Consecutive patients from January 2006 to December 2007 were retrospectively studied.
T8 803-888 Sentence denotes Consecutive patients from January 2006 to December 2007 were retrospectively studied.
T9 889-955 Sentence denotes RESULTS: HBV reactivation happened in 19.1% of patients in 1 year.
T9 889-955 Sentence denotes RESULTS: HBV reactivation happened in 19.1% of patients in 1 year.
T10 956-1053 Sentence denotes There were 28 patients whose HBV reactivation was detected after the diagnosis of HCC recurrence.
T10 956-1053 Sentence denotes There were 28 patients whose HBV reactivation was detected after the diagnosis of HCC recurrence.
T11 1054-1470 Sentence denotes On multivariate analysis, hepatitis B e antigen (HBeAg) positivity, preoperative HBV-DNA above the lower limit of quantification (≥200 IU/mL), Ishak inflammation score of greater than 3, preoperative transarterial chemoembolization (TACE), operation time of more than 180 minutes, blood transfusion, and without prophylactic antiviral therapy were significantly associated with an increased risk of HBV reactivation.
T11 1054-1470 Sentence denotes On multivariate analysis, hepatitis B e antigen (HBeAg) positivity, preoperative HBV-DNA above the lower limit of quantification (≥200 IU/mL), Ishak inflammation score of greater than 3, preoperative transarterial chemoembolization (TACE), operation time of more than 180 minutes, blood transfusion, and without prophylactic antiviral therapy were significantly associated with an increased risk of HBV reactivation.
T12 1471-1542 Sentence denotes HBV reactivation negatively influenced postoperative hepatic functions.
T12 1471-1542 Sentence denotes HBV reactivation negatively influenced postoperative hepatic functions.
T13 1543-1703 Sentence denotes The posthepatectomy liver failure rate in patients with HBV reactivation was significantly higher than in those without reactivation (11.8% vs 6.4%; P = 0.002).
T13 1543-1703 Sentence denotes The posthepatectomy liver failure rate in patients with HBV reactivation was significantly higher than in those without reactivation (11.8% vs 6.4%; P = 0.002).
T14 1704-1960 Sentence denotes The 3-year disease-free survival (DFS) rate and overall survival (OS) rates after resection in patients with HBV reactivation were significantly lower than those without reactivation (34.1% vs 46.0%; P = 0.009, and 51.6% vs 67.2%; P < 0.001, respectively).
T14 1704-1960 Sentence denotes The 3-year disease-free survival (DFS) rate and overall survival (OS) rates after resection in patients with HBV reactivation were significantly lower than those without reactivation (34.1% vs 46.0%; P = 0.009, and 51.6% vs 67.2%; P < 0.001, respectively).
T15 1961-2226 Sentence denotes HBeAg positivity, detectable preoperative HBV-DNA level, high Ishak inflammation score, preoperative TACE, long operation time, and blood transfusion were independent risk factors for HBV reactivation, whereas prophylactic antiviral therapy was a protective factor.
T15 1961-2226 Sentence denotes HBeAg positivity, detectable preoperative HBV-DNA level, high Ishak inflammation score, preoperative TACE, long operation time, and blood transfusion were independent risk factors for HBV reactivation, whereas prophylactic antiviral therapy was a protective factor.
T16 2227-2499 Sentence denotes HBV reactivation, HBeAg positivity, HBV-DNA level of 200 IU/mL or more, tumor diameter greater than 5 cm, presence of satellite nodules, presence of portal vein tumor thrombus, blood transfusion, and resection margin less than 1.0 cm were independent risk factors for DFS.
T16 2227-2499 Sentence denotes HBV reactivation, HBeAg positivity, HBV-DNA level of 200 IU/mL or more, tumor diameter greater than 5 cm, presence of satellite nodules, presence of portal vein tumor thrombus, blood transfusion, and resection margin less than 1.0 cm were independent risk factors for DFS.
T17 2500-2824 Sentence denotes A HBV-DNA level of 200 IU/mL or more, an Ishak fibrosis score of 4 or greater, a tumor diameter greater than 5 cm, the presence of satellite nodules, the presence of portal vein tumor thrombus, a resection margin less than 1.0 cm, no prophylactic antiviral therapy, and HBV reactivation were independent risk factors for OS.
T17 2500-2824 Sentence denotes A HBV-DNA level of 200 IU/mL or more, an Ishak fibrosis score of 4 or greater, a tumor diameter greater than 5 cm, the presence of satellite nodules, the presence of portal vein tumor thrombus, a resection margin less than 1.0 cm, no prophylactic antiviral therapy, and HBV reactivation were independent risk factors for OS.
T18 2825-2974 Sentence denotes CONCLUSIONS: HBV reactivation was common after partial hepatectomy for HBV-related HCC with a preoperative low HBV-DNA level of less than 2000 IU/mL.
T18 2825-2974 Sentence denotes CONCLUSIONS: HBV reactivation was common after partial hepatectomy for HBV-related HCC with a preoperative low HBV-DNA level of less than 2000 IU/mL.
T19 2975-3059 Sentence denotes Routine prophylactic antiviral treatment should be given before partial hepatectomy.
T19 2975-3059 Sentence denotes Routine prophylactic antiviral treatment should be given before partial hepatectomy.