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PubMed:22330637 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-102 Sentence denotes Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence.
T1 0-102 Sentence denotes Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence.
T2 103-274 Sentence denotes We evaluated expression of TLR2, TLR4 and proinflammatory genes [NF-κB, TNF-α, cyclooxygenase-2 (COX-2)] in liver samples of patients in different stages of liver disease.
T2 103-274 Sentence denotes We evaluated expression of TLR2, TLR4 and proinflammatory genes [NF-κB, TNF-α, cyclooxygenase-2 (COX-2)] in liver samples of patients in different stages of liver disease.
T3 275-562 Sentence denotes Fifteen patients with unexplained transaminases elevation (reference group), 22 with viral chronic hepatitis (hepatitis group), 14 with virus-induced severe fibrosis/cirrhosis (cirrhosis group) and 10 with hepatocarcinoma (hepatocarcinoma group) were consecutively included in the study.
T3 275-562 Sentence denotes Fifteen patients with unexplained transaminases elevation (reference group), 22 with viral chronic hepatitis (hepatitis group), 14 with virus-induced severe fibrosis/cirrhosis (cirrhosis group) and 10 with hepatocarcinoma (hepatocarcinoma group) were consecutively included in the study.
T4 563-725 Sentence denotes Quantification of TLR2, TLR4, NF-κB, TNF-α and COX-2 mRNA was done by real-time RT-PCR and TLR2 and TLR4 protein expression was evaluated by immunohistochemistry.
T4 563-725 Sentence denotes Quantification of TLR2, TLR4, NF-κB, TNF-α and COX-2 mRNA was done by real-time RT-PCR and TLR2 and TLR4 protein expression was evaluated by immunohistochemistry.
T5 726-803 Sentence denotes Compared with reference, TLR2 and TLR4 mRNA was increased in hepatitis (TLR2:
T5 726-803 Sentence denotes Compared with reference, TLR2 and TLR4 mRNA was increased in hepatitis (TLR2:
T6 804-822 Sentence denotes 2.66 ± 0.69; TLR4:
T6 804-822 Sentence denotes 2.66 ± 0.69; TLR4:
T7 823-866 Sentence denotes 3.11 ± 0.79; P < 0.05) and cirrhosis (TLR2:
T7 823-866 Sentence denotes 3.11 ± 0.79; P < 0.05) and cirrhosis (TLR2:
T8 867-884 Sentence denotes 2.14 ± 0.5; TLR4:
T8 867-884 Sentence denotes 2.14 ± 0.5; TLR4:
T9 885-947 Sentence denotes 1.74 ± 0.27; P < 0.05) and decreased in hepatocarcinoma (TLR2:
T9 885-947 Sentence denotes 1.74 ± 0.27; P < 0.05) and decreased in hepatocarcinoma (TLR2:
T10 948-966 Sentence denotes 0.48 ± 0.15; TLR4:
T10 948-966 Sentence denotes 0.48 ± 0.15; TLR4:
T11 967-990 Sentence denotes 0.54 ± 0.10; P < 0.05).
T11 967-990 Sentence denotes 0.54 ± 0.10; P < 0.05).
T12 991-1063 Sentence denotes This associated with increased TNF-α and COX-2 mRNA in hepatitis (TNF-α:
T12 991-1063 Sentence denotes This associated with increased TNF-α and COX-2 mRNA in hepatitis (TNF-α:
T13 1064-1083 Sentence denotes 3.24 ± 0.79; COX-2:
T13 1064-1083 Sentence denotes 3.24 ± 0.79; COX-2:
T14 1084-1128 Sentence denotes 2.47 ± 0.36; P < 0.05) and cirrhosis (TNF-α:
T14 1084-1128 Sentence denotes 2.47 ± 0.36; P < 0.05) and cirrhosis (TNF-α:
T15 1129-1148 Sentence denotes 1.73 ± 0.28; COX-2:
T15 1129-1148 Sentence denotes 1.73 ± 0.28; COX-2:
T16 1149-1292 Sentence denotes 1.8 ± 0.35, P < 0.05), whereas NF-κB mRNA was increased in hepatitis (2.42 ± 0.31; P < 0.05) and unchanged in cirrhosis (1.34 ± 0.17; P = 0.3).
T16 1149-1292 Sentence denotes 1.8 ± 0.35, P < 0.05), whereas NF-κB mRNA was increased in hepatitis (2.42 ± 0.31; P < 0.05) and unchanged in cirrhosis (1.34 ± 0.17; P = 0.3).
T17 1293-1474 Sentence denotes Hepatocarcinoma presented increased COX-2 mRNA (1.63 ± 0.15; P < 0.05) and maintained (at decreased levels) mRNA of NF-κB (0.52 ± 0.12) and TNF-α (0.52 ± 0.12; P < 0.05, all genes).
T17 1293-1474 Sentence denotes Hepatocarcinoma presented increased COX-2 mRNA (1.63 ± 0.15; P < 0.05) and maintained (at decreased levels) mRNA of NF-κB (0.52 ± 0.12) and TNF-α (0.52 ± 0.12; P < 0.05, all genes).
T18 1475-1616 Sentence denotes Immunohistochemistry confirmed increased expression of TLR2 and TLR4 in hepatitis and cirrhosis and maintained expression in hepatocarcinoma.
T18 1475-1616 Sentence denotes Immunohistochemistry confirmed increased expression of TLR2 and TLR4 in hepatitis and cirrhosis and maintained expression in hepatocarcinoma.
T19 1617-1734 Sentence denotes Upregulation of TLR2, TLR4 and their proinflammatory mediators is associated with virus-induced hepatic IFC sequence.
T19 1617-1734 Sentence denotes Upregulation of TLR2, TLR4 and their proinflammatory mediators is associated with virus-induced hepatic IFC sequence.