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PubMed:22131818 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus.
T1 0-97 Sentence denotes Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus.
T2 98-251 Sentence denotes Variants of the osteopontin (OPN) gene have been associated with systemic lupus erythematosus (SLE) susceptibility and cytokine profiles in SLE patients.
T2 98-251 Sentence denotes Variants of the osteopontin (OPN) gene have been associated with systemic lupus erythematosus (SLE) susceptibility and cytokine profiles in SLE patients.
T3 252-346 Sentence denotes It is not known whether these alleles are associated with specific clinical phenotypes in SLE.
T3 252-346 Sentence denotes It is not known whether these alleles are associated with specific clinical phenotypes in SLE.
T4 347-503 Sentence denotes We studied 252 well-characterized SLE patients from a multiethnic cohort, genotyping the rs11730582, rs28357094, rs6532040, and rs9138 SNPs in the OPN gene.
T4 347-503 Sentence denotes We studied 252 well-characterized SLE patients from a multiethnic cohort, genotyping the rs11730582, rs28357094, rs6532040, and rs9138 SNPs in the OPN gene.
T5 504-575 Sentence denotes Ancestry informative markers were used to control for genetic ancestry.
T5 504-575 Sentence denotes Ancestry informative markers were used to control for genetic ancestry.
T6 576-772 Sentence denotes The SLE-risk allele rs9138C in the 3' UTR region was associated with photosensitivity in lupus patients across all ancestral backgrounds (meta-analysis OR = 3.2, 95% CI = 1.6-6.5, P = 1.0 × 10⁻³).
T6 576-772 Sentence denotes The SLE-risk allele rs9138C in the 3' UTR region was associated with photosensitivity in lupus patients across all ancestral backgrounds (meta-analysis OR = 3.2, 95% CI = 1.6-6.5, P = 1.0 × 10⁻³).
T7 773-980 Sentence denotes Additionally, the promoter variant rs11730582C demonstrated suggestive evidence for association with two hematologic traits: thrombocytopenia (OR = 2.1, P = 0.023) and hemolytic anemia (OR = 2.6, P = 0.036).
T7 773-980 Sentence denotes Additionally, the promoter variant rs11730582C demonstrated suggestive evidence for association with two hematologic traits: thrombocytopenia (OR = 2.1, P = 0.023) and hemolytic anemia (OR = 2.6, P = 0.036).
T8 981-1224 Sentence denotes These clinical associations with SNPs in the promoter and 3' UTR regions align with previously reported SLE-susceptibility SNPs in OPN and suggest potential roles for these variants in antibody-mediated cytopenias and skin inflammation in SLE.
T8 981-1224 Sentence denotes These clinical associations with SNPs in the promoter and 3' UTR regions align with previously reported SLE-susceptibility SNPs in OPN and suggest potential roles for these variants in antibody-mediated cytopenias and skin inflammation in SLE.