> top > projects > Inflammaging > docs > PubMed:20959502 > annotations
Inflammaging  

PubMed:20959502 JSONTXT 45 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-102 Sentence denotes Cerebrospinal fluid penetration of high-dose daptomycin in suspected Staphylococcus aureus meningitis.
T1 0-102 Sentence denotes Cerebrospinal fluid penetration of high-dose daptomycin in suspected Staphylococcus aureus meningitis.
T2 103-113 Sentence denotes OBJECTIVE:
T2 103-113 Sentence denotes OBJECTIVE:
T3 114-337 Sentence denotes To report a case of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia with suspected MSSA meningitis treated with high-dose daptomycin assessed with concurrent serum and cerebrospinal fluid (CSF) concentrations.
T3 114-337 Sentence denotes To report a case of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia with suspected MSSA meningitis treated with high-dose daptomycin assessed with concurrent serum and cerebrospinal fluid (CSF) concentrations.
T4 338-351 Sentence denotes CASE SUMMARY:
T4 338-351 Sentence denotes CASE SUMMARY:
T5 352-507 Sentence denotes A 54-year-old male presented to the emergency department with generalized weakness and presumed health-care-associated pneumonia shown on chest radiograph.
T5 352-507 Sentence denotes A 54-year-old male presented to the emergency department with generalized weakness and presumed health-care-associated pneumonia shown on chest radiograph.
T6 508-603 Sentence denotes Treatment was empirically initiated with vancomycin, levofloxacin, and piperacillin/tazobactam.
T6 508-603 Sentence denotes Treatment was empirically initiated with vancomycin, levofloxacin, and piperacillin/tazobactam.
T7 604-663 Sentence denotes Blood cultures revealed S. aureus susceptible to oxacillin.
T7 604-663 Sentence denotes Blood cultures revealed S. aureus susceptible to oxacillin.
T8 664-728 Sentence denotes Empiric antibiotic treatment was narrowed to nafcillin on day 4.
T8 664-728 Sentence denotes Empiric antibiotic treatment was narrowed to nafcillin on day 4.
T9 729-880 Sentence denotes On day 8, the patient developed acute renal failure (serum creatinine 1.9 mg/dL, increased from 1.2 mg/dL the previous day and 0.8 mg/dL on admission).
T9 729-880 Sentence denotes On day 8, the patient developed acute renal failure (serum creatinine 1.9 mg/dL, increased from 1.2 mg/dL the previous day and 0.8 mg/dL on admission).
T10 881-1046 Sentence denotes The patient's Glasgow Coma Score was 3, with normal findings shown on computed tomography scan of the head 72 hours following an episode of cardiac arrest on day 10.
T10 881-1046 Sentence denotes The patient's Glasgow Coma Score was 3, with normal findings shown on computed tomography scan of the head 72 hours following an episode of cardiac arrest on day 10.
T11 1047-1177 Sentence denotes The patient experienced relapsing MSSA bacteremia on day 9, increasing the suspicion for a central nervous system (CNS) infection.
T11 1047-1177 Sentence denotes The patient experienced relapsing MSSA bacteremia on day 9, increasing the suspicion for a central nervous system (CNS) infection.
T12 1178-1327 Sentence denotes Nafcillin was discontinued and daptomycin 9 mg/kg daily was initiated for suspected meningitis and was continued until the patient's death on day 16.
T12 1178-1327 Sentence denotes Nafcillin was discontinued and daptomycin 9 mg/kg daily was initiated for suspected meningitis and was continued until the patient's death on day 16.
T13 1328-1446 Sentence denotes Daptomycin serum and CSF trough concentrations were 11.21 μg/mL and 0.52 μg/mL, respectively, prior to the third dose.
T13 1328-1446 Sentence denotes Daptomycin serum and CSF trough concentrations were 11.21 μg/mL and 0.52 μg/mL, respectively, prior to the third dose.
T14 1447-1542 Sentence denotes Lumbar puncture results were inconclusive and no further blood cultures were positive for MSSA.
T14 1447-1542 Sentence denotes Lumbar puncture results were inconclusive and no further blood cultures were positive for MSSA.
T15 1543-1630 Sentence denotes Creatine kinase levels were normal prior to daptomycin therapy and were not reassessed.
T15 1543-1630 Sentence denotes Creatine kinase levels were normal prior to daptomycin therapy and were not reassessed.
T16 1631-1642 Sentence denotes DISCUSSION:
T16 1631-1642 Sentence denotes DISCUSSION:
T17 1643-1777 Sentence denotes Daptomycin was initiated in our patient secondary to possible nafcillin-induced acute interstitial nephritis and relapsing bacteremia.
T17 1643-1777 Sentence denotes Daptomycin was initiated in our patient secondary to possible nafcillin-induced acute interstitial nephritis and relapsing bacteremia.
T18 1778-1904 Sentence denotes At a dose of 9 mg/kg, resultant penetration of 5% was higher than in previous reports, more consistent with inflamed meninges.
T18 1778-1904 Sentence denotes At a dose of 9 mg/kg, resultant penetration of 5% was higher than in previous reports, more consistent with inflamed meninges.
T19 1905-1917 Sentence denotes CONCLUSIONS:
T19 1905-1917 Sentence denotes CONCLUSIONS:
T20 1918-2081 Sentence denotes High-dose daptomycin may be an alternative option for MSSA bacteremia with or without a CNS source in patients who have failed or cannot tolerate standard therapy.
T20 1918-2081 Sentence denotes High-dose daptomycin may be an alternative option for MSSA bacteremia with or without a CNS source in patients who have failed or cannot tolerate standard therapy.
T21 2082-2161 Sentence denotes Further clinical evaluation in patients with confirmed meningitis is warranted.
T21 2082-2161 Sentence denotes Further clinical evaluation in patients with confirmed meningitis is warranted.