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PubMed:1978333 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-88 Sentence denotes Resistance to human serum of gonococci in urethral exudates is reduced by neuraminidase.
T1 0-88 Sentence denotes Resistance to human serum of gonococci in urethral exudates is reduced by neuraminidase.
T2 89-231 Sentence denotes Gonococci examined directly from urethral exudates are resistant to killing by human serum, but most strains become susceptible on subculture.
T2 89-231 Sentence denotes Gonococci examined directly from urethral exudates are resistant to killing by human serum, but most strains become susceptible on subculture.
T3 232-573 Sentence denotes Previous work with gonococci grown in vitro indicates that resistance in vivo is due to sialylation of gonococcal lipopolysaccharide (LPS) by a host factor, cytidine 5'-monophospho-N-acetylneuraminic acid (CMP-NANA) or a related compound present in urogenital secretions and blood cells including phagocytes, which exude during inflammation.
T3 232-573 Sentence denotes Previous work with gonococci grown in vitro indicates that resistance in vivo is due to sialylation of gonococcal lipopolysaccharide (LPS) by a host factor, cytidine 5'-monophospho-N-acetylneuraminic acid (CMP-NANA) or a related compound present in urogenital secretions and blood cells including phagocytes, which exude during inflammation.
T4 574-672 Sentence denotes This sialylation inhibits the reaction between bactericidal IgM in serum and its target LPS sites.
T4 574-672 Sentence denotes This sialylation inhibits the reaction between bactericidal IgM in serum and its target LPS sites.
T5 673-738 Sentence denotes Here, we confirm the indication by using gonococci grown in vivo.
T5 673-738 Sentence denotes Here, we confirm the indication by using gonococci grown in vivo.
T6 739-922 Sentence denotes Crucial to the above conclusions was the marked reduction of CMP-NANA-conferred serum resistance when gonococci were treated with neuraminidase to remove sialyl groups from their LPS.
T6 739-922 Sentence denotes Crucial to the above conclusions was the marked reduction of CMP-NANA-conferred serum resistance when gonococci were treated with neuraminidase to remove sialyl groups from their LPS.
T7 923-1172 Sentence denotes We now show that the serum resistance of gonococci in urethral exudates was reduced by treatment with neuraminidase from more than 95% (calculated in relation to controls incubated with heated serum) to 2-11% according to sample and incubation time.
T7 923-1172 Sentence denotes We now show that the serum resistance of gonococci in urethral exudates was reduced by treatment with neuraminidase from more than 95% (calculated in relation to controls incubated with heated serum) to 2-11% according to sample and incubation time.
T8 1173-1307 Sentence denotes Subculture of the gonococci also reduced resistance to 9-11% but resistance was restored to more than 95% by incubation with CMP-NANA.
T8 1173-1307 Sentence denotes Subculture of the gonococci also reduced resistance to 9-11% but resistance was restored to more than 95% by incubation with CMP-NANA.
T9 1308-1502 Sentence denotes This work is the culmination of an investigation that underlines the need to identify specific host factors and the virulence determinants they induce in vivo in future studies of pathogenicity.
T9 1308-1502 Sentence denotes This work is the culmination of an investigation that underlines the need to identify specific host factors and the virulence determinants they induce in vivo in future studies of pathogenicity.