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PubMed:19707748 JSONTXT 27 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T1 0-79 Sentence denotes Seizures associated with levofloxacin: case presentation and literature review.
T1 0-79 Sentence denotes Seizures associated with levofloxacin: case presentation and literature review.
T2 80-88 Sentence denotes PURPOSE:
T2 80-88 Sentence denotes PURPOSE:
T3 89-377 Sentence denotes We present a case of a patient who developed seizures shortly after initiating treatment with levofloxacin and to discuss the potential drug-drug interactions related to the inhibition of cytochrome P450 (CYP) 1A2 in this case, as well as in other cases, of levofloxacin-induced seizures.
T3 89-377 Sentence denotes We present a case of a patient who developed seizures shortly after initiating treatment with levofloxacin and to discuss the potential drug-drug interactions related to the inhibition of cytochrome P450 (CYP) 1A2 in this case, as well as in other cases, of levofloxacin-induced seizures.
T4 378-386 Sentence denotes METHODS:
T4 378-386 Sentence denotes METHODS:
T5 387-467 Sentence denotes Several biomedical databases were searched including MEDLINE, Cochrane and Ovid.
T5 387-467 Sentence denotes Several biomedical databases were searched including MEDLINE, Cochrane and Ovid.
T6 468-533 Sentence denotes The main search terms utilized were case report and levofloxacin.
T6 468-533 Sentence denotes The main search terms utilized were case report and levofloxacin.
T7 534-589 Sentence denotes The search was limited to studies published in English.
T7 534-589 Sentence denotes The search was limited to studies published in English.
T8 590-598 Sentence denotes RESULTS:
T8 590-598 Sentence denotes RESULTS:
T9 599-679 Sentence denotes Six cases of levofloxacin-induced seizures have been reported in the literature.
T9 599-679 Sentence denotes Six cases of levofloxacin-induced seizures have been reported in the literature.
T10 680-814 Sentence denotes Drug-drug interactions related to the inhibition of CYP1A2 by levofloxacin are likely involved in the clinical outcome of these cases.
T10 680-814 Sentence denotes Drug-drug interactions related to the inhibition of CYP1A2 by levofloxacin are likely involved in the clinical outcome of these cases.
T11 815-827 Sentence denotes CONCLUSIONS:
T11 815-827 Sentence denotes CONCLUSIONS:
T12 828-1000 Sentence denotes Clinicians are exhorted to pay close attention when initiating levofloxacin therapy in patients taking medications with epileptogenic properties that are CYP1A2 substrates.
T12 828-1000 Sentence denotes Clinicians are exhorted to pay close attention when initiating levofloxacin therapy in patients taking medications with epileptogenic properties that are CYP1A2 substrates.