| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-78 |
Sentence |
denotes |
Angiotensin converting enzyme gene polymorphism in Turkish asthmatic patients. |
| T1 |
0-78 |
Sentence |
denotes |
Angiotensin converting enzyme gene polymorphism in Turkish asthmatic patients. |
| T2 |
79-135 |
Sentence |
denotes |
Asthma is a chronic inflammatory disease of the airways. |
| T2 |
79-135 |
Sentence |
denotes |
Asthma is a chronic inflammatory disease of the airways. |
| T3 |
136-289 |
Sentence |
denotes |
Several candidate genes have been identified with a potential role in the pathogenesis of asthma, including the angiotensin converting enzyme (ACE) gene. |
| T3 |
136-289 |
Sentence |
denotes |
Several candidate genes have been identified with a potential role in the pathogenesis of asthma, including the angiotensin converting enzyme (ACE) gene. |
| T4 |
290-458 |
Sentence |
denotes |
We aimed to investigate the frequency of an ACE gene polymorphism in Turkish asthmatic patients and to determine its impact on clinical parameters and disease severity. |
| T4 |
290-458 |
Sentence |
denotes |
We aimed to investigate the frequency of an ACE gene polymorphism in Turkish asthmatic patients and to determine its impact on clinical parameters and disease severity. |
| T5 |
459-605 |
Sentence |
denotes |
Ninety-seven asthmatic patients (M/F 25/72, mean age 39 +/- 13 years) and 96 healthy subjects (M/F 26/70, mean age 38 +/- 12 years) were included. |
| T5 |
459-605 |
Sentence |
denotes |
Ninety-seven asthmatic patients (M/F 25/72, mean age 39 +/- 13 years) and 96 healthy subjects (M/F 26/70, mean age 38 +/- 12 years) were included. |
| T6 |
606-757 |
Sentence |
denotes |
At baseline, all participants completed a questionnaire on demographics, symptoms, triggering factors, severity of asthma, and the presence of atopism. |
| T6 |
606-757 |
Sentence |
denotes |
At baseline, all participants completed a questionnaire on demographics, symptoms, triggering factors, severity of asthma, and the presence of atopism. |
| T7 |
758-833 |
Sentence |
denotes |
Blood samples were obtained from all patients and genomic DNA was isolated. |
| T7 |
758-833 |
Sentence |
denotes |
Blood samples were obtained from all patients and genomic DNA was isolated. |
| T8 |
834-1064 |
Sentence |
denotes |
The frequency of the ACE genotypes (I = insertion and D = deletion) among asthmatics and controls were compared: asthmatics showed a 40.2% prevalence of the DD genotype (n = 39), ID was 45.4% (n = 44), and II was 14.4% (n = 14.4). |
| T8 |
834-1064 |
Sentence |
denotes |
The frequency of the ACE genotypes (I = insertion and D = deletion) among asthmatics and controls were compared: asthmatics showed a 40.2% prevalence of the DD genotype (n = 39), ID was 45.4% (n = 44), and II was 14.4% (n = 14.4). |
| T9 |
1065-1176 |
Sentence |
denotes |
In the control subjects, the frequency of DD was 18.8% (n = 18), ID was 50% (n = 48) and II was 31.3% (n = 30). |
| T9 |
1065-1176 |
Sentence |
denotes |
In the control subjects, the frequency of DD was 18.8% (n = 18), ID was 50% (n = 48) and II was 31.3% (n = 30). |
| T10 |
1177-1278 |
Sentence |
denotes |
The DD ACE genotype was significantly more frequent in asthmatics compared with controls (p < 0.001). |
| T10 |
1177-1278 |
Sentence |
denotes |
The DD ACE genotype was significantly more frequent in asthmatics compared with controls (p < 0.001). |
| T11 |
1279-1419 |
Sentence |
denotes |
Asthmatics with the ID ACE genotype showed a higher frequency of drug allergies, although this was not statistically significant (p = 0.08). |
| T11 |
1279-1419 |
Sentence |
denotes |
Asthmatics with the ID ACE genotype showed a higher frequency of drug allergies, although this was not statistically significant (p = 0.08). |
| T12 |
1420-1608 |
Sentence |
denotes |
Asthmatics with the DD genotype appeared to have a higher incidence of asthmatic episode exacerbations due to viral infections, but again this was not statistically significant (p = 0.08). |
| T12 |
1420-1608 |
Sentence |
denotes |
Asthmatics with the DD genotype appeared to have a higher incidence of asthmatic episode exacerbations due to viral infections, but again this was not statistically significant (p = 0.08). |
| T13 |
1609-1697 |
Sentence |
denotes |
Patients with mild or moderate-severe asthma had similar frequencies of these mutations. |
| T13 |
1609-1697 |
Sentence |
denotes |
Patients with mild or moderate-severe asthma had similar frequencies of these mutations. |
| T14 |
1698-1939 |
Sentence |
denotes |
We found a higher frequency of the ACE DD gene mutation in Turkish asthmatic patients compared with non-asthmatics, suggesting that this ACE gene polymorphism may be a risk factor for asthma but does not increase the severity of the disease. |
| T14 |
1698-1939 |
Sentence |
denotes |
We found a higher frequency of the ACE DD gene mutation in Turkish asthmatic patients compared with non-asthmatics, suggesting that this ACE gene polymorphism may be a risk factor for asthma but does not increase the severity of the disease. |