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PubMed:1909740 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines.
T1 0-81 Sentence denotes Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines.
T2 82-163 Sentence denotes Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization.
T2 82-163 Sentence denotes Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization.
T3 164-257 Sentence denotes The cytokine TNF mediates many of the pathologic signs of cachexia, inflammation, and sepsis.
T3 164-257 Sentence denotes The cytokine TNF mediates many of the pathologic signs of cachexia, inflammation, and sepsis.
T4 258-364 Sentence denotes The current work describes the regulation of TNF in human myelomonocytic cell lines after PMA stimulation.
T4 258-364 Sentence denotes The current work describes the regulation of TNF in human myelomonocytic cell lines after PMA stimulation.
T5 365-436 Sentence denotes The cell lines exhibit a low level of constitutive TNF mRNA expression.
T5 365-436 Sentence denotes The cell lines exhibit a low level of constitutive TNF mRNA expression.
T6 437-565 Sentence denotes Within 2 to 4 h of PMA exposure, steady state levels of TNF mRNA are markedly elevated in all myelomonocytic cell lines studied.
T6 437-565 Sentence denotes Within 2 to 4 h of PMA exposure, steady state levels of TNF mRNA are markedly elevated in all myelomonocytic cell lines studied.
T7 566-725 Sentence denotes This rise is due to increased mRNA stability, which increased by almost twofold, and to an overall increase in transcription, which rises by more than sixfold.
T7 566-725 Sentence denotes This rise is due to increased mRNA stability, which increased by almost twofold, and to an overall increase in transcription, which rises by more than sixfold.
T8 726-900 Sentence denotes At the level of the genomic TNF gene, a DNase I hypersensitive site is detected within the TNF promoter between -200 to -100 bp relative to the transcription initiation site.
T8 726-900 Sentence denotes At the level of the genomic TNF gene, a DNase I hypersensitive site is detected within the TNF promoter between -200 to -100 bp relative to the transcription initiation site.
T9 901-1068 Sentence denotes Although absent in nonexpressing erythroleukemia cell lines, the DNase I site is present in uninduced myelomonocytic cell lines and is not changed after PMA induction.
T9 901-1068 Sentence denotes Although absent in nonexpressing erythroleukemia cell lines, the DNase I site is present in uninduced myelomonocytic cell lines and is not changed after PMA induction.
T10 1069-1247 Sentence denotes The PMA induction of c-fos mRNA correlated well with TNF gene induction; expression of genes encoding other proteins in the AP-1 complex (junB and junD) were also induced by PMA.
T10 1069-1247 Sentence denotes The PMA induction of c-fos mRNA correlated well with TNF gene induction; expression of genes encoding other proteins in the AP-1 complex (junB and junD) were also induced by PMA.
T11 1248-1418 Sentence denotes The nuclear extracts from resting and induced ML-1 cells contain proteins binding specifically to the AP-1, AP-2, and NF kappa B sequence located within the TNF promoter.
T11 1248-1418 Sentence denotes The nuclear extracts from resting and induced ML-1 cells contain proteins binding specifically to the AP-1, AP-2, and NF kappa B sequence located within the TNF promoter.
T12 1419-1525 Sentence denotes PMA induction increases the level of a number of specific binding complexes relative to the resting cells.
T12 1419-1525 Sentence denotes PMA induction increases the level of a number of specific binding complexes relative to the resting cells.
T13 1526-1600 Sentence denotes The regulatory mechanisms of the human and murine TNF genes are discussed.
T13 1526-1600 Sentence denotes The regulatory mechanisms of the human and murine TNF genes are discussed.