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PubMed:15858075 JSONTXT 61 Projects

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Id Subject Object Predicate Lexical cue
T1 0-105 Sentence denotes Increased sialylation and defucosylation of plasma proteins are early events in the acute phase response.
T1 0-105 Sentence denotes Increased sialylation and defucosylation of plasma proteins are early events in the acute phase response.
T2 106-308 Sentence denotes Within hours of turpentine injection to stimulate the acute phase (AP) response in rats, the N-acetylneuraminic acid content of plasma proteins increases and that of fucose decreases, each by about 60%.
T2 106-308 Sentence denotes Within hours of turpentine injection to stimulate the acute phase (AP) response in rats, the N-acetylneuraminic acid content of plasma proteins increases and that of fucose decreases, each by about 60%.
T3 309-359 Sentence denotes The two changes are inversely related (r = -0.97).
T3 309-359 Sentence denotes The two changes are inversely related (r = -0.97).
T4 360-437 Sentence denotes The NeuAc/Gal ratio increases from the normal 0.75 to 1.0 on day 2 of the AP.
T4 360-437 Sentence denotes The NeuAc/Gal ratio increases from the normal 0.75 to 1.0 on day 2 of the AP.
T5 438-607 Sentence denotes Whereas 50% of the isolated oligosaccharides of normal plasma proteins are retarded on immobilized Ricinus communis agglutinin, those from day 2 AP plasma fail to do so.
T5 438-607 Sentence denotes Whereas 50% of the isolated oligosaccharides of normal plasma proteins are retarded on immobilized Ricinus communis agglutinin, those from day 2 AP plasma fail to do so.
T6 608-982 Sentence denotes This indicates that NeuAc caps the normally Gal-terminated chains. alpha1-Acid glycoprotein (a positive AP protein), alpha1-macroglobulin (a non-AP protein), and alpha1-inhibitor3 (a negative AP protein) also show similar alterations in NeuAc/Gal ratio and decreases in Fuc. alpha2-Macroglobulin, which arises only during the AP, does not contain significant amounts of Fuc.
T6 608-982 Sentence denotes This indicates that NeuAc caps the normally Gal-terminated chains. alpha1-Acid glycoprotein (a positive AP protein), alpha1-macroglobulin (a non-AP protein), and alpha1-inhibitor3 (a negative AP protein) also show similar alterations in NeuAc/Gal ratio and decreases in Fuc. alpha2-Macroglobulin, which arises only during the AP, does not contain significant amounts of Fuc.
T7 983-1127 Sentence denotes Sambucus nigra agglutinin (alpha2,6-linked NeuAc-specific) binds a majority of plasma proteins, and binding is increased during the AP response.
T7 983-1127 Sentence denotes Sambucus nigra agglutinin (alpha2,6-linked NeuAc-specific) binds a majority of plasma proteins, and binding is increased during the AP response.
T8 1128-1272 Sentence denotes Maackia amurensis lectin (alpha2,3-linked NeuAc-specific) binds only three proteins in normal plasma and three additional proteins in AP plasma.
T8 1128-1272 Sentence denotes Maackia amurensis lectin (alpha2,3-linked NeuAc-specific) binds only three proteins in normal plasma and three additional proteins in AP plasma.
T9 1273-1391 Sentence denotes The Fuc-specific Aleuria aurantia agglutinin and Lens culinaris agglutinin each detect five proteins in normal plasma.
T9 1273-1391 Sentence denotes The Fuc-specific Aleuria aurantia agglutinin and Lens culinaris agglutinin each detect five proteins in normal plasma.
T10 1392-1439 Sentence denotes Their binding decreases during the AP response.
T10 1392-1439 Sentence denotes Their binding decreases during the AP response.
T11 1440-1722 Sentence denotes These results show that: (1) sialylation and defucosylation of preexisting plasma proteins occur rapidly in the AP response; (2) sialylation caps the preexisting Gal-terminating oligosaccharides; and (3) the oligosaccharides of even the non-AP and negative AP proteins are modified.
T11 1440-1722 Sentence denotes These results show that: (1) sialylation and defucosylation of preexisting plasma proteins occur rapidly in the AP response; (2) sialylation caps the preexisting Gal-terminating oligosaccharides; and (3) the oligosaccharides of even the non-AP and negative AP proteins are modified.
T12 1723-1919 Sentence denotes These changes are distinct from the elevation in the levels of protein-bound monosaccharides and the altered concanavalin A-binding profile the oligosaccharides of AP proteins acquire in diseases.
T12 1723-1919 Sentence denotes These changes are distinct from the elevation in the levels of protein-bound monosaccharides and the altered concanavalin A-binding profile the oligosaccharides of AP proteins acquire in diseases.