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PubMed:15748645 JSONTXT 24 Projects

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Id Subject Object Predicate Lexical cue
T1 0-72 Sentence denotes Photochemoprevention of ultraviolet B signaling and photocarcinogenesis.
T1 0-72 Sentence denotes Photochemoprevention of ultraviolet B signaling and photocarcinogenesis.
T2 73-198 Sentence denotes Exposure to solar radiation, particularly its ultraviolet (UV) B component, has a variety of harmful effects on human health.
T2 73-198 Sentence denotes Exposure to solar radiation, particularly its ultraviolet (UV) B component, has a variety of harmful effects on human health.
T3 199-354 Sentence denotes Some of these effects include sunburn cell formation, basal and squamous cell cancers, melanoma, cataracts, photoaging of the skin, and immune suppression.
T3 199-354 Sentence denotes Some of these effects include sunburn cell formation, basal and squamous cell cancers, melanoma, cataracts, photoaging of the skin, and immune suppression.
T4 355-449 Sentence denotes Amongst these various adverse effects of UV radiation, skin cancer is of the greatest concern.
T4 355-449 Sentence denotes Amongst these various adverse effects of UV radiation, skin cancer is of the greatest concern.
T5 450-645 Sentence denotes Over the years, changes in lifestyle has led to a significant increase in the amount of UV radiation that people receive, and this consequently has led to a surge in the incidence of skin cancer.
T5 450-645 Sentence denotes Over the years, changes in lifestyle has led to a significant increase in the amount of UV radiation that people receive, and this consequently has led to a surge in the incidence of skin cancer.
T6 646-804 Sentence denotes The development of skin cancer is a complex multistage phenomenon involving three distinct stages exemplified by initiation, promotion and progression stages.
T6 646-804 Sentence denotes The development of skin cancer is a complex multistage phenomenon involving three distinct stages exemplified by initiation, promotion and progression stages.
T7 805-910 Sentence denotes Each of these stages is mediated via alterations in various cellular, biochemical, and molecular changes.
T7 805-910 Sentence denotes Each of these stages is mediated via alterations in various cellular, biochemical, and molecular changes.
T8 911-1115 Sentence denotes Initiation, the first step in the carcinogenesis process is essentially an irreversible step in which genetic alterations occur in genes that ultimately leads to DNA modification and fixation of mutation.
T8 911-1115 Sentence denotes Initiation, the first step in the carcinogenesis process is essentially an irreversible step in which genetic alterations occur in genes that ultimately leads to DNA modification and fixation of mutation.
T9 1116-1344 Sentence denotes Tumor promotion is the essential process in cancer development involving clonal expansion of initiated cells giving rise to pre-malignant and then to malignant lesions, essentially by alterations in signal transduction pathways.
T9 1116-1344 Sentence denotes Tumor promotion is the essential process in cancer development involving clonal expansion of initiated cells giving rise to pre-malignant and then to malignant lesions, essentially by alterations in signal transduction pathways.
T10 1345-1486 Sentence denotes Tumor progression involves the conversion of pre-malignant and malignant lesions into an invasive and potentially metastatic malignant tumor.
T10 1345-1486 Sentence denotes Tumor progression involves the conversion of pre-malignant and malignant lesions into an invasive and potentially metastatic malignant tumor.
T11 1487-1871 Sentence denotes All these processes for skin cancer development involve stimulation of DNA synthesis, DNA damage and proliferation, inflammation, immunosuppression, epidermal hyperplasia, cell cycle dysregulation, depletion of antioxidant defenses, impairment of signal transduction pathways, induction of cyclooxygenase, increase in prostaglandin synthesis, and induction of ornithine decarboxylase.
T11 1487-1871 Sentence denotes All these processes for skin cancer development involve stimulation of DNA synthesis, DNA damage and proliferation, inflammation, immunosuppression, epidermal hyperplasia, cell cycle dysregulation, depletion of antioxidant defenses, impairment of signal transduction pathways, induction of cyclooxygenase, increase in prostaglandin synthesis, and induction of ornithine decarboxylase.
T12 1872-2200 Sentence denotes Photochemoprevention has been appreciated as a viable approach to reduce the occurrence of skin cancer and in recent years, the use of agents, especially botanical antioxidants, present in the common diet and beverages consumed by human population have gained considerable attention as photochemopreventive agents for human use.
T12 1872-2200 Sentence denotes Photochemoprevention has been appreciated as a viable approach to reduce the occurrence of skin cancer and in recent years, the use of agents, especially botanical antioxidants, present in the common diet and beverages consumed by human population have gained considerable attention as photochemopreventive agents for human use.
T13 2201-2264 Sentence denotes Many such agents have also found a place in skin care products.
T13 2201-2264 Sentence denotes Many such agents have also found a place in skin care products.
T14 2265-2378 Sentence denotes Although this is more common in oriental countries, its popularity is significantly growing in western countries.
T14 2265-2378 Sentence denotes Although this is more common in oriental countries, its popularity is significantly growing in western countries.
T15 2379-2547 Sentence denotes In this article, we have summarized the available information of laboratory studies on UVB-mediated signaling that can be exploited as targets for photochemoprevention.
T15 2379-2547 Sentence denotes In this article, we have summarized the available information of laboratory studies on UVB-mediated signaling that can be exploited as targets for photochemoprevention.
T16 2548-2806 Sentence denotes We suggest that the use of skin care products supplemented with proven chemopreventive agents in conjunction with the use of sunscreens along with educational efforts may be an effective strategy for reducing UV-induced photodamage and skin cancer in humans.
T16 2548-2806 Sentence denotes We suggest that the use of skin care products supplemented with proven chemopreventive agents in conjunction with the use of sunscreens along with educational efforts may be an effective strategy for reducing UV-induced photodamage and skin cancer in humans.
T17 2807-2871 Sentence denotes The mechanistic basis for the use of such products is discussed.
T17 2807-2871 Sentence denotes The mechanistic basis for the use of such products is discussed.