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PubMed:15648059 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Investigation of genes coding for inflammatory components in Parkinson's disease.
T1 0-81 Sentence denotes Investigation of genes coding for inflammatory components in Parkinson's disease.
T2 82-207 Sentence denotes Several findings obtained recently indicate that inflammation may contribute to the pathogenesis in Parkinson's disease (PD).
T2 82-207 Sentence denotes Several findings obtained recently indicate that inflammation may contribute to the pathogenesis in Parkinson's disease (PD).
T3 208-378 Sentence denotes Genetic variants of genes coding for components involved in immune reactions in the brain might therefore influence the risk of developing PD or the age of disease onset.
T3 208-378 Sentence denotes Genetic variants of genes coding for components involved in immune reactions in the brain might therefore influence the risk of developing PD or the age of disease onset.
T4 379-806 Sentence denotes Five single nucleotide polymorphisms (SNPs) in the genes coding for interferon-gamma (IFN-gamma; T874A in intron 1), interferon-gamma receptor 2 (IFN-gamma R2; Gln64Arg), interleukin-10 (IL-10; G1082A in the promoter region), platelet-activating factor acetylhydrolase (PAF-AH; Val379Ala), and intercellular adhesion molecule 1 (ICAM-1; Lys469Glu) were genotyped, using pyrosequencing, in 265 patients with PD and 308 controls.
T4 379-806 Sentence denotes Five single nucleotide polymorphisms (SNPs) in the genes coding for interferon-gamma (IFN-gamma; T874A in intron 1), interferon-gamma receptor 2 (IFN-gamma R2; Gln64Arg), interleukin-10 (IL-10; G1082A in the promoter region), platelet-activating factor acetylhydrolase (PAF-AH; Val379Ala), and intercellular adhesion molecule 1 (ICAM-1; Lys469Glu) were genotyped, using pyrosequencing, in 265 patients with PD and 308 controls.
T5 807-985 Sentence denotes None of the investigated SNPs was found to be associated with PD; however, the G1082A polymorphism in the IL-10 gene promoter was found to be related to the age of disease onset.
T5 807-985 Sentence denotes None of the investigated SNPs was found to be associated with PD; however, the G1082A polymorphism in the IL-10 gene promoter was found to be related to the age of disease onset.
T6 986-1257 Sentence denotes Linear regression showed a significantly earlier onset with more A-alleles (P = 0.0095; after Bonferroni correction, P = 0.048), resulting in a 5-year delayed age of onset of the disease for individuals having two G-alleles compared with individuals having two A-alleles.
T6 986-1257 Sentence denotes Linear regression showed a significantly earlier onset with more A-alleles (P = 0.0095; after Bonferroni correction, P = 0.048), resulting in a 5-year delayed age of onset of the disease for individuals having two G-alleles compared with individuals having two A-alleles.
T7 1258-1357 Sentence denotes The results indicate that the IL-10 G1082A SNP could possibly be related to the age of onset of PD.
T7 1258-1357 Sentence denotes The results indicate that the IL-10 G1082A SNP could possibly be related to the age of onset of PD.