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PubMed:14559780 JSONTXT 4 Projects

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Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway.
T1 0-101 Sentence denotes Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway.
T2 102-251 Sentence denotes In this study, we propose a system-theoretic approach to the analysis and quantitative modeling of the TNFalpha-mediated NF-kappaB-signaling pathway.
T2 102-251 Sentence denotes In this study, we propose a system-theoretic approach to the analysis and quantitative modeling of the TNFalpha-mediated NF-kappaB-signaling pathway.
T3 252-456 Sentence denotes Tumor necrosis factor alpha (TNFalpha) is a potent proinflammatory cytokine that plays an important role in immunity and inflammation, in the control of cell proliferation, differentiation, and apoptosis.
T3 252-456 Sentence denotes Tumor necrosis factor alpha (TNFalpha) is a potent proinflammatory cytokine that plays an important role in immunity and inflammation, in the control of cell proliferation, differentiation, and apoptosis.
T4 457-529 Sentence denotes To date, there have been numerous approaches to model cellular dynamics.
T4 457-529 Sentence denotes To date, there have been numerous approaches to model cellular dynamics.
T5 530-627 Sentence denotes The most prominent uses ordinary differential equations (ODEs) to describe biochemical reactions.
T5 530-627 Sentence denotes The most prominent uses ordinary differential equations (ODEs) to describe biochemical reactions.
T6 628-792 Sentence denotes This approach can provide us with mathematically well-founded and tractable interpretations regarding pathways, especially those best described by enzyme reactions.
T6 628-792 Sentence denotes This approach can provide us with mathematically well-founded and tractable interpretations regarding pathways, especially those best described by enzyme reactions.
T7 793-973 Sentence denotes This work first introduces a graphical method to intuitively represent the TNFalpha-mediated NF-kappaB-signaling pathway and then utilizes ODEs to quantitatively model the pathway.
T7 793-973 Sentence denotes This work first introduces a graphical method to intuitively represent the TNFalpha-mediated NF-kappaB-signaling pathway and then utilizes ODEs to quantitatively model the pathway.
T8 974-1098 Sentence denotes The simulation study shows qualitative validation of the proposed model compared with experimental results for this pathway.
T8 974-1098 Sentence denotes The simulation study shows qualitative validation of the proposed model compared with experimental results for this pathway.
T9 1099-1289 Sentence denotes The proposed system-theoretic approach is expected to be further applicable to predict the signaling behavior of NF-kappaB in a quantitative manner for any variation of the ligand, TNFalpha.
T9 1099-1289 Sentence denotes The proposed system-theoretic approach is expected to be further applicable to predict the signaling behavior of NF-kappaB in a quantitative manner for any variation of the ligand, TNFalpha.