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Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-71 Sentence denotes Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.
T1 0-71 Sentence denotes Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.
T2 72-288 Sentence denotes The NF-kappa B/Rel family of transcription factors participates in the control of a wide array of genes, including genes involved in embryonic development and regulation of immune, inflammation, and stress responses.
T2 72-288 Sentence denotes The NF-kappa B/Rel family of transcription factors participates in the control of a wide array of genes, including genes involved in embryonic development and regulation of immune, inflammation, and stress responses.
T3 289-376 Sentence denotes In most cells, inhibitory I kappa B proteins sequester NF-kappa B/Rel in the cytoplasm.
T3 289-376 Sentence denotes In most cells, inhibitory I kappa B proteins sequester NF-kappa B/Rel in the cytoplasm.
T4 377-565 Sentence denotes Cellular stimulation results in the degradation of I kappa B and modification of NF-kappa B/Rel proteins, allowing NF-kappa B/Rel to translocate to the nucleus and act on its target genes.
T4 377-565 Sentence denotes Cellular stimulation results in the degradation of I kappa B and modification of NF-kappa B/Rel proteins, allowing NF-kappa B/Rel to translocate to the nucleus and act on its target genes.
T5 566-714 Sentence denotes Calmodulin (CaM) is a highly conserved, ubiquitously expressed Ca(2+) binding protein that serves as a key mediator of intracellular Ca(2+) signals.
T5 566-714 Sentence denotes Calmodulin (CaM) is a highly conserved, ubiquitously expressed Ca(2+) binding protein that serves as a key mediator of intracellular Ca(2+) signals.
T6 715-834 Sentence denotes Here we report that two members of the NF-kappa B/Rel family, c-Rel and RelA, interact directly with Ca(2+)-loaded CaM.
T6 715-834 Sentence denotes Here we report that two members of the NF-kappa B/Rel family, c-Rel and RelA, interact directly with Ca(2+)-loaded CaM.
T7 835-1056 Sentence denotes The interaction with CaM is greatly enhanced by cell stimulation, and this enhancement is blocked by addition of I kappa B. c-Rel and RelA interact with CaM through a similar sequence near the nuclear localization signal.
T7 835-1056 Sentence denotes The interaction with CaM is greatly enhanced by cell stimulation, and this enhancement is blocked by addition of I kappa B. c-Rel and RelA interact with CaM through a similar sequence near the nuclear localization signal.
T8 1057-1326 Sentence denotes Compared to the wild-type protein, CaM binding-deficient mutants of c-Rel exhibit increases in both nuclear accumulation and transcriptional activity on the interleukin 2 and granulocyte macrophage colony-stimulating factor promoters in the presence of a Ca(2+) signal.
T8 1057-1326 Sentence denotes Compared to the wild-type protein, CaM binding-deficient mutants of c-Rel exhibit increases in both nuclear accumulation and transcriptional activity on the interleukin 2 and granulocyte macrophage colony-stimulating factor promoters in the presence of a Ca(2+) signal.
T9 1327-1487 Sentence denotes Conversely, for RelA neither nuclear accumulation nor transcriptional activity on these promoters is increased by mutation of the sequence interacting with CaM.
T9 1327-1487 Sentence denotes Conversely, for RelA neither nuclear accumulation nor transcriptional activity on these promoters is increased by mutation of the sequence interacting with CaM.
T10 1488-1687 Sentence denotes Our results suggest that CaM binds c-Rel and RelA after their release from I kappa B and can inhibit nuclear import of c-Rel while letting RelA translocate to the nucleus and act on its target genes.
T10 1488-1687 Sentence denotes Our results suggest that CaM binds c-Rel and RelA after their release from I kappa B and can inhibit nuclear import of c-Rel while letting RelA translocate to the nucleus and act on its target genes.
T11 1688-1794 Sentence denotes CaM can therefore differentially regulate the activation of NF-kappa B/Rel proteins following stimulation.
T11 1688-1794 Sentence denotes CaM can therefore differentially regulate the activation of NF-kappa B/Rel proteins following stimulation.