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PubMed:10783313 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T1 0-96 Sentence denotes Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.
T1 0-96 Sentence denotes Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.
T2 97-304 Sentence denotes Epidemiological studies consistently indicate that consumption of fruits and vegetables lowers cancer risk in humans and suggest that certain dietary constituents may be effective in preventing colon cancer.
T2 97-304 Sentence denotes Epidemiological studies consistently indicate that consumption of fruits and vegetables lowers cancer risk in humans and suggest that certain dietary constituents may be effective in preventing colon cancer.
T3 305-440 Sentence denotes Plant-derived phenolic compounds manifest many beneficial effects and can potentially inhibit several stages of carcinogenesis in vivo.
T3 305-440 Sentence denotes Plant-derived phenolic compounds manifest many beneficial effects and can potentially inhibit several stages of carcinogenesis in vivo.
T4 441-659 Sentence denotes In this study, we investigated the efficacy of several plant-derived phenolics, including caffeic acid phenethyl ester (CAPE), curcumin, quercetin and rutin, for the prevention of tumors in C57BL/6J-Min/+ (Min/+) mice.
T4 441-659 Sentence denotes In this study, we investigated the efficacy of several plant-derived phenolics, including caffeic acid phenethyl ester (CAPE), curcumin, quercetin and rutin, for the prevention of tumors in C57BL/6J-Min/+ (Min/+) mice.
T5 660-789 Sentence denotes These animals bear a germline mutation in the Apc gene and spontaneously develop numerous intestinal adenomas by 15 weeks of age.
T5 660-789 Sentence denotes These animals bear a germline mutation in the Apc gene and spontaneously develop numerous intestinal adenomas by 15 weeks of age.
T6 790-871 Sentence denotes At a dietary level of 0.15%, CAPE decreased tumor formation in Min/+ mice by 63%.
T6 790-871 Sentence denotes At a dietary level of 0.15%, CAPE decreased tumor formation in Min/+ mice by 63%.
T7 872-916 Sentence denotes Curcumin induced a similar tumor inhibition.
T7 872-916 Sentence denotes Curcumin induced a similar tumor inhibition.
T8 917-1008 Sentence denotes Quercetin and rutin, however, both failed to alter tumor formation at dietary levels of 2%.
T8 917-1008 Sentence denotes Quercetin and rutin, however, both failed to alter tumor formation at dietary levels of 2%.
T9 1009-1186 Sentence denotes Examination of intestinal tissue from the treated animals showed that tumor prevention by CAPE and curcumin was associated with increased enterocyte apoptosis and proliferation.
T9 1009-1186 Sentence denotes Examination of intestinal tissue from the treated animals showed that tumor prevention by CAPE and curcumin was associated with increased enterocyte apoptosis and proliferation.
T10 1187-1364 Sentence denotes CAPE and curcumin also decreased expression of the oncoprotein beta-catenin in the enterocytes of the Min/+ mouse, an observation previously associated with an antitumor effect.
T10 1187-1364 Sentence denotes CAPE and curcumin also decreased expression of the oncoprotein beta-catenin in the enterocytes of the Min/+ mouse, an observation previously associated with an antitumor effect.
T11 1365-1524 Sentence denotes These data place the plant phenolics CAPE and curcumin among a growing list of anti-inflammatory agents that suppress Apc-associated intestinal carcinogenesis.
T11 1365-1524 Sentence denotes These data place the plant phenolics CAPE and curcumin among a growing list of anti-inflammatory agents that suppress Apc-associated intestinal carcinogenesis.