> top > projects > Inflammaging > docs > PubMed:10764835 > annotations

Inflammaging

PubMed:10764835 JSON TXT 85 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id	Subject	Object	Predicate	Lexical cue
T1	0-73	Sentence	denotes	Heparanase expression in invasive trophoblasts and acute vascular damage.
T1	0-73	Sentence	denotes	Heparanase expression in invasive trophoblasts and acute vascular damage.
T2	74-184	Sentence	denotes	Heparan sulfate proteoglycans play a pivotal role in tissue function, development, inflammation, and immunity.
T2	74-184	Sentence	denotes	Heparan sulfate proteoglycans play a pivotal role in tissue function, development, inflammation, and immunity.
T3	185-370	Sentence	denotes	We have identified a novel cDNA encoding human heparanase, an enzyme thought to cleave heparan sulfate in physiology and disease, and have located the HEP gene on human chromosome 4q21.
T3	185-370	Sentence	denotes	We have identified a novel cDNA encoding human heparanase, an enzyme thought to cleave heparan sulfate in physiology and disease, and have located the HEP gene on human chromosome 4q21.
T4	371-618	Sentence	denotes	Monoclonal antibodies against human heparanase located the enzyme along invasive extravillous trophoblasts of human placenta and along endothelial cells in organ xenografts targeted by hyperacute rejection, both sites of heparan sulfate digestion.
T4	371-618	Sentence	denotes	Monoclonal antibodies against human heparanase located the enzyme along invasive extravillous trophoblasts of human placenta and along endothelial cells in organ xenografts targeted by hyperacute rejection, both sites of heparan sulfate digestion.
T5	619-800	Sentence	denotes	Heparanase deposition was evident in arterial walls in normal tissues; however, vascular heparan sulfate cleavage was coincident with heparanase enzyme during inflammatory episodes.
T5	619-800	Sentence	denotes	Heparanase deposition was evident in arterial walls in normal tissues; however, vascular heparan sulfate cleavage was coincident with heparanase enzyme during inflammatory episodes.
T6	801-1035	Sentence	denotes	These findings suggest that heparanase elaboration and control of catalytic activity may contribute to the development and pathogenesis of vascular disease and suggest that heparanase intervention might be a useful therapeutic target.
T6	801-1035	Sentence	denotes	These findings suggest that heparanase elaboration and control of catalytic activity may contribute to the development and pathogenesis of vascular disease and suggest that heparanase intervention might be a useful therapeutic target.