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PubMed:10561251 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T1 0-117 Sentence denotes Outcomes of high-dose chemotherapy and autologous stem-cell transplantation in stage IIIB inflammatory breast cancer.
T1 0-117 Sentence denotes Outcomes of high-dose chemotherapy and autologous stem-cell transplantation in stage IIIB inflammatory breast cancer.
T2 118-126 Sentence denotes PURPOSE:
T2 118-126 Sentence denotes PURPOSE:
T3 127-429 Sentence denotes To evaluate the disease-free survival (DFS) and overall survival (OS), prognostic factors, and treatment-related mortality of women with stage IIIB inflammatory breast cancer (IBC) treated with combined modality therapy (CMT) and high-dose chemotherapy (HDCT) with autologous stem-cell transplantation.
T3 127-429 Sentence denotes To evaluate the disease-free survival (DFS) and overall survival (OS), prognostic factors, and treatment-related mortality of women with stage IIIB inflammatory breast cancer (IBC) treated with combined modality therapy (CMT) and high-dose chemotherapy (HDCT) with autologous stem-cell transplantation.
T4 430-451 Sentence denotes PATIENTS AND METHODS:
T4 430-451 Sentence denotes PATIENTS AND METHODS:
T5 452-602 Sentence denotes Between 1989 and 1997, 47 consecutive patients with stage IIIB IBC were treated with CMT and HDCT and were the subject of this retrospective analysis.
T5 452-602 Sentence denotes Between 1989 and 1997, 47 consecutive patients with stage IIIB IBC were treated with CMT and HDCT and were the subject of this retrospective analysis.
T6 603-688 Sentence denotes Chemotherapy was administered to all patients before and/or after definitive surgery.
T6 603-688 Sentence denotes Chemotherapy was administered to all patients before and/or after definitive surgery.
T7 689-811 Sentence denotes Neoadjuvant and adjuvant chemotherapy was administered to 33 and 34 patients, respectively, and 20 patients received both.
T7 689-811 Sentence denotes Neoadjuvant and adjuvant chemotherapy was administered to 33 and 34 patients, respectively, and 20 patients received both.
T8 812-938 Sentence denotes All patients received HDCT with autologous stem-cell transplantation, and 41 patients received locoregional radiation therapy.
T8 812-938 Sentence denotes All patients received HDCT with autologous stem-cell transplantation, and 41 patients received locoregional radiation therapy.
T9 939-1020 Sentence denotes Tamoxifen was prescribed to patients with estrogen receptor (ER)-positive cancer.
T9 939-1020 Sentence denotes Tamoxifen was prescribed to patients with estrogen receptor (ER)-positive cancer.
T10 1021-1029 Sentence denotes RESULTS:
T10 1021-1029 Sentence denotes RESULTS:
T11 1030-1168 Sentence denotes The mean duration of follow-up from diagnosis was 30 months (range, 6 to 91 months) and from HDCT was 22 months (range, 0.5 to 82 months).
T11 1030-1168 Sentence denotes The mean duration of follow-up from diagnosis was 30 months (range, 6 to 91 months) and from HDCT was 22 months (range, 0.5 to 82 months).
T12 1169-1274 Sentence denotes At 30 months, the Kaplan-Meier estimates of DFS and OS from diagnosis were 57.7% and 59.1%, respectively.
T12 1169-1274 Sentence denotes At 30 months, the Kaplan-Meier estimates of DFS and OS from diagnosis were 57.7% and 59.1%, respectively.
T13 1275-1378 Sentence denotes At 4 years, the Kaplan-Meier estimates of DFS and OS from diagnosis were 51.3% and 51.7%, respectively.
T13 1275-1378 Sentence denotes At 4 years, the Kaplan-Meier estimates of DFS and OS from diagnosis were 51.3% and 51.7%, respectively.
T14 1379-1651 Sentence denotes In a multivariate analysis, the only factors associated with better survival were favorable response to neoadjuvant chemotherapy (P =.04) and receipt of tamoxifen (P =.06); however, the benefit of tamoxifen was only demonstrated in patients with ER-positive breast cancer.
T14 1379-1651 Sentence denotes In a multivariate analysis, the only factors associated with better survival were favorable response to neoadjuvant chemotherapy (P =.04) and receipt of tamoxifen (P =.06); however, the benefit of tamoxifen was only demonstrated in patients with ER-positive breast cancer.
T15 1652-1687 Sentence denotes At last follow-up, 28 patients (59.
T15 1652-1687 Sentence denotes At last follow-up, 28 patients (59.
T16 1688-1720 Sentence denotes 6%) were alive and disease-free.
T16 1688-1720 Sentence denotes 6%) were alive and disease-free.
T17 1721-1782 Sentence denotes Seventeen patients (36.2%) developed recurrent breast cancer.
T17 1721-1782 Sentence denotes Seventeen patients (36.2%) developed recurrent breast cancer.
T18 1783-1807 Sentence denotes Seventeen patients died:
T18 1783-1807 Sentence denotes Seventeen patients died:
T19 1808-1895 Sentence denotes 15 from disease recurrence and two (4.2%) from treatment-related mortality due to HDCT.
T19 1808-1895 Sentence denotes 15 from disease recurrence and two (4.2%) from treatment-related mortality due to HDCT.
T20 1896-1907 Sentence denotes CONCLUSION:
T20 1896-1907 Sentence denotes CONCLUSION:
T21 1908-2066 Sentence denotes In this analysis, the early results of treatment with CMT and HDCT compare favorably with other series of patients with stage IIIB IBC treated with CMT alone.
T21 1908-2066 Sentence denotes In this analysis, the early results of treatment with CMT and HDCT compare favorably with other series of patients with stage IIIB IBC treated with CMT alone.
T22 2067-2145 Sentence denotes These outcomes must be confirmed with longer follow-up and controlled studies.
T22 2067-2145 Sentence denotes These outcomes must be confirmed with longer follow-up and controlled studies.