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PubMed:10449169 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-61 Sentence denotes Dendritic cells and the pathogenesis of rheumatoid arthritis.
T1 0-61 Sentence denotes Dendritic cells and the pathogenesis of rheumatoid arthritis.
T2 62-203 Sentence denotes Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease in which unknown arthrogenic autoantigen is presented to CD4+ T cells.
T2 62-203 Sentence denotes Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease in which unknown arthrogenic autoantigen is presented to CD4+ T cells.
T3 204-382 Sentence denotes The strong association of the disease with an epitope within the HLA-DR chain shared between various alleles of HLA-DR4 and DR1 emphasizes the importance of antigen presentation.
T3 204-382 Sentence denotes The strong association of the disease with an epitope within the HLA-DR chain shared between various alleles of HLA-DR4 and DR1 emphasizes the importance of antigen presentation.
T4 383-565 Sentence denotes This immune response predominantly occurs in the synovial tissue and fluid of the joints and autoreactive T cells are readily demonstrable in both the synovial compartment and blood.
T4 383-565 Sentence denotes This immune response predominantly occurs in the synovial tissue and fluid of the joints and autoreactive T cells are readily demonstrable in both the synovial compartment and blood.
T5 566-682 Sentence denotes Circulating dendritic cells (DC) are phenotypically and functionally identical with normal peripheral blood (PB) DC.
T5 566-682 Sentence denotes Circulating dendritic cells (DC) are phenotypically and functionally identical with normal peripheral blood (PB) DC.
T6 683-850 Sentence denotes In the synovial tissue, fully differentiated perivascular DC are found in close association with T cells and with B cell follicles, sometimes containing follicular DC.
T6 683-850 Sentence denotes In the synovial tissue, fully differentiated perivascular DC are found in close association with T cells and with B cell follicles, sometimes containing follicular DC.
T7 851-1035 Sentence denotes These perivascular DC migrate across the activated endothelium from blood and receive differentiative signals within the joint from monocyte-derived cytokines and CD40-ligand+ T cells.
T7 851-1035 Sentence denotes These perivascular DC migrate across the activated endothelium from blood and receive differentiative signals within the joint from monocyte-derived cytokines and CD40-ligand+ T cells.
T8 1036-1134 Sentence denotes In the SF, DC manifest an intermediate phenotype, similar to that of monocyte-derived DC in vitro.
T8 1036-1134 Sentence denotes In the SF, DC manifest an intermediate phenotype, similar to that of monocyte-derived DC in vitro.
T9 1135-1234 Sentence denotes Like a delayed-type hypersensitivity response, the rheumatoid synovium represents an effector site.
T9 1135-1234 Sentence denotes Like a delayed-type hypersensitivity response, the rheumatoid synovium represents an effector site.
T10 1235-1327 Sentence denotes DC at many effector sites have a characteristic pattern of infiltration and differentiation.
T10 1235-1327 Sentence denotes DC at many effector sites have a characteristic pattern of infiltration and differentiation.
T11 1328-1430 Sentence denotes It is important to note that the effector response is not self-limiting in RA autoimmune inflammation.
T11 1328-1430 Sentence denotes It is important to note that the effector response is not self-limiting in RA autoimmune inflammation.
T12 1431-1599 Sentence denotes In this article, we argue that the presentation of self-antigen by DC and by autoantibody-producing B cells is critical for the perpetuation of the autoimmune response.
T12 1431-1599 Sentence denotes In this article, we argue that the presentation of self-antigen by DC and by autoantibody-producing B cells is critical for the perpetuation of the autoimmune response.
T13 1600-1738 Sentence denotes Permanently arresting this ongoing immune response with either pharmaceutical agents or immunotherapy is a major challenge for immunology.
T13 1600-1738 Sentence denotes Permanently arresting this ongoing immune response with either pharmaceutical agents or immunotherapy is a major challenge for immunology.