| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-107 |
Sentence |
denotes |
Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes. |
| T1 |
0-107 |
Sentence |
denotes |
Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes. |
| T2 |
108-191 |
Sentence |
denotes |
The renin-angiotensin system may contribute to the pathogenesis of atherosclerosis. |
| T2 |
108-191 |
Sentence |
denotes |
The renin-angiotensin system may contribute to the pathogenesis of atherosclerosis. |
| T3 |
192-277 |
Sentence |
denotes |
A common feature of all stages of atherosclerosis is inflammation of the vessel wall. |
| T3 |
192-277 |
Sentence |
denotes |
A common feature of all stages of atherosclerosis is inflammation of the vessel wall. |
| T4 |
278-402 |
Sentence |
denotes |
The transcription factor nuclear factor-kappaB (NF-kappaB) participates in most signaling pathways involved in inflammation. |
| T4 |
278-402 |
Sentence |
denotes |
The transcription factor nuclear factor-kappaB (NF-kappaB) participates in most signaling pathways involved in inflammation. |
| T5 |
403-598 |
Sentence |
denotes |
This study therefore examined the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma, by electrophoretic mobility shift assay. |
| T5 |
403-598 |
Sentence |
denotes |
This study therefore examined the effect of angiotensin (ANG) II on NF-kappaB activation in monocytic cells, a major cellular component of human atheroma, by electrophoretic mobility shift assay. |
| T6 |
599-744 |
Sentence |
denotes |
ANG II, like TNFalpha, caused rapid activation of NF-kappaB in human mononuclear cells isolated from peripheral blood by Ficoll density gradient. |
| T6 |
599-744 |
Sentence |
denotes |
ANG II, like TNFalpha, caused rapid activation of NF-kappaB in human mononuclear cells isolated from peripheral blood by Ficoll density gradient. |
| T7 |
745-828 |
Sentence |
denotes |
This ANG II effect was blocked by the angiotensin AT1 receptor antagonist losartan. |
| T7 |
745-828 |
Sentence |
denotes |
This ANG II effect was blocked by the angiotensin AT1 receptor antagonist losartan. |
| T8 |
829-938 |
Sentence |
denotes |
Specificity of ANG II-induced NF-kappaB activation was ascertained by supershift and competition experiments. |
| T8 |
829-938 |
Sentence |
denotes |
Specificity of ANG II-induced NF-kappaB activation was ascertained by supershift and competition experiments. |
| T9 |
939-1057 |
Sentence |
denotes |
Moreover, ANG II stimulated NF-kappaB activation in human monocytes, but not in lymphocytes from the same preparation. |
| T9 |
939-1057 |
Sentence |
denotes |
Moreover, ANG II stimulated NF-kappaB activation in human monocytes, but not in lymphocytes from the same preparation. |
| T10 |
1058-1187 |
Sentence |
denotes |
Together, the data demonstrate the ability of the vasoactive peptide ANG II to activate inflammatory pathways in human monocytes. |
| T10 |
1058-1187 |
Sentence |
denotes |
Together, the data demonstrate the ability of the vasoactive peptide ANG II to activate inflammatory pathways in human monocytes. |