> top > projects > Inflammaging > docs > PubMed:10202027 > annotations
Inflammaging  

PubMed:10202027 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.
T1 0-106 Sentence denotes Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.
T2 107-165 Sentence denotes Chlamydia pneumoniae is an important respiratory pathogen.
T2 107-165 Sentence denotes Chlamydia pneumoniae is an important respiratory pathogen.
T3 166-238 Sentence denotes Recently, its presence has been demonstrated in atherosclerotic lesions.
T3 166-238 Sentence denotes Recently, its presence has been demonstrated in atherosclerotic lesions.
T4 239-501 Sentence denotes In this study, we characterized C. pneumoniae-mediated activation of endothelial cells and demonstrated an enhanced expression of endothelial adhesion molecules followed by subsequent rolling, adhesion, and transmigration of leukocytes (monocytes, granulocytes).
T4 239-501 Sentence denotes In this study, we characterized C. pneumoniae-mediated activation of endothelial cells and demonstrated an enhanced expression of endothelial adhesion molecules followed by subsequent rolling, adhesion, and transmigration of leukocytes (monocytes, granulocytes).
T5 502-621 Sentence denotes These effects were blocked by mAbs against endothelial and/or leukocyte adhesion molecules (beta1 and beta2 integrins).
T5 502-621 Sentence denotes These effects were blocked by mAbs against endothelial and/or leukocyte adhesion molecules (beta1 and beta2 integrins).
T6 622-917 Sentence denotes Additionally, activation of different signal transduction pathways in C. pneumoniae-infected endothelial cells was shown: protein tyrosine phosphorylation, up-regulation of phosphorylated p42/p44 mitogen-activated protein kinase, and NF-kappaB activation/translocation occurred within 10-15 min.
T6 622-917 Sentence denotes Additionally, activation of different signal transduction pathways in C. pneumoniae-infected endothelial cells was shown: protein tyrosine phosphorylation, up-regulation of phosphorylated p42/p44 mitogen-activated protein kinase, and NF-kappaB activation/translocation occurred within 10-15 min.
T7 918-1014 Sentence denotes Increased mRNA and surface expression of E-selectin, ICAM-1, and VCAM-1 were noted within hours.
T7 918-1014 Sentence denotes Increased mRNA and surface expression of E-selectin, ICAM-1, and VCAM-1 were noted within hours.
T8 1015-1196 Sentence denotes Thus, C. pneumoniae triggers a cascade of events that could lead to endothelial activation, inflammation, and thrombosis, which in turn may result in or may promote atherosclerosis.
T8 1015-1196 Sentence denotes Thus, C. pneumoniae triggers a cascade of events that could lead to endothelial activation, inflammation, and thrombosis, which in turn may result in or may promote atherosclerosis.