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PubMed:10101001 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-81 Sentence denotes Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB.
T1 0-81 Sentence denotes Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB.
T2 82-304 Sentence denotes Acute inflammatory injury in rat lung induced by deposition of immunoglobulin G immune complexes requires expression of cytokines and chemokines as well as activation of the transcription factor nuclear factor (NF)-kappaB.
T2 82-304 Sentence denotes Acute inflammatory injury in rat lung induced by deposition of immunoglobulin G immune complexes requires expression of cytokines and chemokines as well as activation of the transcription factor nuclear factor (NF)-kappaB.
T3 305-407 Sentence denotes There is little direct evidence regarding the role of alveolar macrophages in these activation events.
T3 305-407 Sentence denotes There is little direct evidence regarding the role of alveolar macrophages in these activation events.
T4 408-560 Sentence denotes In the present studies, rat lungs were depleted of alveolar macrophages by airway instillation of liposome-encapsulated dichloromethylene diphosphonate.
T4 408-560 Sentence denotes In the present studies, rat lungs were depleted of alveolar macrophages by airway instillation of liposome-encapsulated dichloromethylene diphosphonate.
T5 561-715 Sentence denotes These procedures, which greatly reduced the number of retrievable alveolar macrophages, suppressed activation of lung NF-kappaB in the inflammatory model.
T5 561-715 Sentence denotes These procedures, which greatly reduced the number of retrievable alveolar macrophages, suppressed activation of lung NF-kappaB in the inflammatory model.
T6 716-887 Sentence denotes In addition, bronchoalveolar lavage levels of tumor necrosis factor-alpha (TNF-alpha) and the CXC chemokine, macrophage inflammatory protein-2, were substantially reduced.
T6 716-887 Sentence denotes In addition, bronchoalveolar lavage levels of tumor necrosis factor-alpha (TNF-alpha) and the CXC chemokine, macrophage inflammatory protein-2, were substantially reduced.
T7 888-1076 Sentence denotes In parallel, upregulation of the lung vascular adhesion molecule, intercellular adhesion molecule-1, was greatly reduced by intrapulmonary instillation of phosphonate-containing liposomes.
T7 888-1076 Sentence denotes In parallel, upregulation of the lung vascular adhesion molecule, intercellular adhesion molecule-1, was greatly reduced by intrapulmonary instillation of phosphonate-containing liposomes.
T8 1077-1167 Sentence denotes Neutrophil accumulation and development of lung injury were also substantially diminished.
T8 1077-1167 Sentence denotes Neutrophil accumulation and development of lung injury were also substantially diminished.
T9 1168-1293 Sentence denotes Lung instillation of TNF-alpha in alveolar macrophage-depleted rats restored the NF-kappaB activation response in whole lung.
T9 1168-1293 Sentence denotes Lung instillation of TNF-alpha in alveolar macrophage-depleted rats restored the NF-kappaB activation response in whole lung.
T10 1294-1517 Sentence denotes These data suggest that, in this inflammatory model, initial activation of NF-kappaB occurs in alveolar macrophages and the ensuing production of TNF-alpha may propagate NF-kappaB activation to other cell types in the lung.
T10 1294-1517 Sentence denotes These data suggest that, in this inflammatory model, initial activation of NF-kappaB occurs in alveolar macrophages and the ensuing production of TNF-alpha may propagate NF-kappaB activation to other cell types in the lung.