| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-71 |
Sentence |
denotes |
Interferon-beta mediates stromal cell rescue of T cells from apoptosis. |
| T1 |
0-71 |
Sentence |
denotes |
Interferon-beta mediates stromal cell rescue of T cells from apoptosis. |
| T2 |
72-168 |
Sentence |
denotes |
The resolution of immune responses is characterized by extensive apoptosis of activated T cells. |
| T2 |
72-168 |
Sentence |
denotes |
The resolution of immune responses is characterized by extensive apoptosis of activated T cells. |
| T3 |
169-304 |
Sentence |
denotes |
However, to generate and maintain immunological memory, some antigen-specific T cells must survive and revert to a resting G0/G1 state. |
| T3 |
169-304 |
Sentence |
denotes |
However, to generate and maintain immunological memory, some antigen-specific T cells must survive and revert to a resting G0/G1 state. |
| T4 |
305-441 |
Sentence |
denotes |
Cytokines that bind to the common gamma chain of the IL-2 receptor promote the survival of T cell blasts, but also induce proliferation. |
| T4 |
305-441 |
Sentence |
denotes |
Cytokines that bind to the common gamma chain of the IL-2 receptor promote the survival of T cell blasts, but also induce proliferation. |
| T5 |
442-544 |
Sentence |
denotes |
In contrast, soluble factors secreted by stromal cells induce Tcell survival in a resting G0/G1 state. |
| T5 |
442-544 |
Sentence |
denotes |
In contrast, soluble factors secreted by stromal cells induce Tcell survival in a resting G0/G1 state. |
| T6 |
545-659 |
Sentence |
denotes |
We now report that interferon-beta is the principal mediator of stromal cell-mediated Tcell rescue from apoptosis. |
| T6 |
545-659 |
Sentence |
denotes |
We now report that interferon-beta is the principal mediator of stromal cell-mediated Tcell rescue from apoptosis. |
| T7 |
660-864 |
Sentence |
denotes |
Interferon-alpha and -beta promote the reversion of blast Tcells to a resting G0/G1 configuration with all the characteristic features of stromal cell rescue; such as high Bcl-XL expression and low Bcl-2. |
| T7 |
660-864 |
Sentence |
denotes |
Interferon-alpha and -beta promote the reversion of blast Tcells to a resting G0/G1 configuration with all the characteristic features of stromal cell rescue; such as high Bcl-XL expression and low Bcl-2. |
| T8 |
865-982 |
Sentence |
denotes |
Type I interferons and stromal cells stimulate apparently identical signaling pathways, leading to STAT-1 activation. |
| T8 |
865-982 |
Sentence |
denotes |
Type I interferons and stromal cells stimulate apparently identical signaling pathways, leading to STAT-1 activation. |
| T9 |
983-1196 |
Sentence |
denotes |
We also show that this mechanism may play a fundamental role in the persistence of T cells at sites of chronic inflammation; suggesting that chronic inflammation is an aberrant consequence of immunological memory. |
| T9 |
983-1196 |
Sentence |
denotes |
We also show that this mechanism may play a fundamental role in the persistence of T cells at sites of chronic inflammation; suggesting that chronic inflammation is an aberrant consequence of immunological memory. |