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PubMed:10037799 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-94 Sentence denotes LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan.
T1 0-94 Sentence denotes LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan.
T2 95-311 Sentence denotes The extracellular matrix glycosaminoglycan hyaluronan (HA) is an abundant component of skin and mesenchymal tissues where it facilitates cell migration during wound healing, inflammation, and embryonic morphogenesis.
T2 95-311 Sentence denotes The extracellular matrix glycosaminoglycan hyaluronan (HA) is an abundant component of skin and mesenchymal tissues where it facilitates cell migration during wound healing, inflammation, and embryonic morphogenesis.
T3 312-549 Sentence denotes Both during normal tissue homeostasis and particularly after tissue injury, HA is mobilized from these sites through lymphatic vessels to the lymph nodes where it is degraded before entering the circulation for rapid uptake by the liver.
T3 312-549 Sentence denotes Both during normal tissue homeostasis and particularly after tissue injury, HA is mobilized from these sites through lymphatic vessels to the lymph nodes where it is degraded before entering the circulation for rapid uptake by the liver.
T4 550-648 Sentence denotes Currently, however, the identities of HA binding molecules which control this pathway are unknown.
T4 550-648 Sentence denotes Currently, however, the identities of HA binding molecules which control this pathway are unknown.
T5 649-776 Sentence denotes Here we describe the first such molecule, LYVE-1, which we have identified as a major receptor for HA on the lymph vessel wall.
T5 649-776 Sentence denotes Here we describe the first such molecule, LYVE-1, which we have identified as a major receptor for HA on the lymph vessel wall.
T6 777-1052 Sentence denotes The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily.
T6 777-1052 Sentence denotes The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily.
T7 1053-1122 Sentence denotes Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA.
T7 1053-1122 Sentence denotes Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA.
T8 1123-1274 Sentence denotes However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels.
T8 1123-1274 Sentence denotes However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels.
T9 1275-1412 Sentence denotes Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
T9 1275-1412 Sentence denotes Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.