Gene_Chemical

Documents (109) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	10477429	TP53 mutation and haplotype analysis of two large African American families. Two large apparently unrelated African American families with a high incidence of breast cancer and other tumors characteri	1.38 KB	2015-11-21	2	-
PubMed	10485478	Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers. The M6P/IGF2R gene, encoding the insulin-like growth factor II (IGF-I	1.89 KB	2015-11-21	2	-
PubMed	10534763	Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer. Epidemiological studies have shown an increased risk of breast cancer in obligate	1.76 KB	2015-11-15	4	-
PubMed	10547570	Altered expression of p53 and its regulated proteins in phyllodes tumours of the breast. The histological characteristics of phyllodes tumours of the breast are often not related to their clinical out	1.36 KB	2015-11-21	4	-
PubMed	10698474	Genetic polymorphism of cytochrome P450-1B1 and risk of breast cancer. Cytochrome P450-1B1 (CYP1B1) is a major enzyme catalyzing the formation of genotoxic 4-hydroxyestradiol. This enzyme is also invo	1.59 KB	2015-11-15	5	-
PubMed	10901165	Identification of p53 gene mutations in breast cancers and their effects on transcriptional activation function. Somatic mutations in the p53 tumor suppressor gene are the most common genetic alterati	1.67 KB	2015-11-15	6	-
PubMed	11212236	Inhibiting mutations in the transforming growth factor beta type 2 receptor in recurrent human breast cancer. Members of the transforming growth factor beta (TGF-beta) family are potent inhibitors of	1.73 KB	2015-11-17	4	-
PubMed	11369138	Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. Lobular carcinoma in situ (LCIS) is an unusual histological pattern of non-invasive neoplastic disease of t	1.12 KB	2015-11-17	4	-
PubMed	11434510	Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer. There is evidence suggesting that polymorphic variations in the glutathione S-transferases (	2.01 KB	2015-11-17	2	-
PubMed	11705864	Association of E-cadherin germ-line alterations with prostate cancer. In our recent cancer registry-based study, the incidence of gastric carcinoma was increased up to 5-fold in male relatives of earl	1.67 KB	2015-11-17	5	-