Gene_Chemical

Documents (109) JSON TSV

source DB	source ID	text	size	updated at	# proj.	updated_at
PubMed	14691288	Androgen receptor mutations in high-grade prostate cancer before hormonal therapy. Androgen action is mediated through androgen receptor (AR), which appears to undergo structural and functional altera	1.31 KB	2015-11-18	4	-
PubMed	15042566	DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy. BACKGROUND: Aristolochic acid-associated nephropathy (AAN) is a specific type of renal disease that predispose	1.29 KB	2015-11-18	11	-
PubMed	15059511	[Germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in China Han people]. OBJECTIVE: To detect BRCA1 and BRCA2 gene germline mutation in the Chinese breast cancer families. ME	1.63 KB	2015-11-22	1	-
PubMed	15101044	Functional consequences of ATM sequence variants for chromosomal radiosensitivity. The ATM [for ataxia-telangiectasia (A-T) mutated] protein plays a key role in the detection and cellular response to	1.61 KB	2015-11-18	5	-
PubMed	15146458	Identification of a functional mutation in pp32r1 (ANP32C). No mutations or polymorphisms have previously been reported in pp32r1 (ANP32C; GenBank: AF008216.1). pp32r1 is part of the highly conserved	1.51 KB	2015-11-19	4	-
PubMed	15170666	The variant E233G of the RAD51D gene could be a low-penetrance allele in high-risk breast cancer families without BRCA1/2 mutations. Six SNPs have been detected in the DNA repair genes RAD51C and RAD5	1.09 KB	2015-11-22	4	-
PubMed	15217503	No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer. INTRODUCTION: Mutations in BRCA	1.7 KB	2015-11-19	4	-
PubMed	15235021	Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria. BACKGROUND: Mutations in the E-cadherin (CDH1) gene are a we	1.76 KB	2015-11-19	4	-
PubMed	15342448	Glutathione S-transferases M1, T1, and P1 and breast cancer: a pooled analysis. The glutathione S-transferase (GST) genes are involved in the metabolism of various carcinogens. Deletion polymorphisms	1.66 KB	2015-11-19	4	-
PubMed	15617028	Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics. BACKGROUND: Alterations in the function of androgen receptor (AR) and its signaling pathway	2.04 KB	2015-11-18	3	-