Epistemic_Statements  

CORD-19:cbab61c03b58e81082109fa56830f400890485fc JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 726-780 Epistemic_statement denotes It included 20 (62.50%) males and 12 (37.50%) females.
T2 819-1010 Epistemic_statement denotes Diagnosis was done by real-time reverse transcription polymerase chain reaction (rRT-PCR) test for corona virus on throat swab, sputum, tracheal aspirate, or bronchoalveolar lavage specimens.
T3 1508-1604 Epistemic_statement denotes Out of the included 32 patients, 18 patients (56.25%) survived and 14 patients (43.75%) expired.
T4 1605-1812 Epistemic_statement denotes There was a statistically significant difference in the duration of symptoms before hospitalization, mechanical ventilation and ICU and total hospital stay between the expired group and survivors (P < 0.01).
T5 1945-2072 Epistemic_statement denotes Also, there was a statistically (P < 0.05) significant positive correlation between mortality and smoking severity (r = 0.640).
T6 2073-2337 Epistemic_statement denotes Most of the expired patients presented with bilateral pulmonary infiltrates or unilateral infiltrates, but most of the survivors presented with normal This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
T7 2338-2470 Epistemic_statement denotes radiology or increased bronchovascular markings, and this difference in the results was statistically highly significant (P < 0.01).
T8 2471-2739 Epistemic_statement denotes There were statistically highly significant (P < 0.01) differences in the mean values of APACHE II score (21.11 ± 3.70 vs 24.21 ± 3.82), SOFA score (5.83 ± 2.64 vs 8.85 ± 2.17) and CPIS (7.55 ± 1.14 vs 8.64 ± 1.39) between the expired group and survivors respectively.
T9 2961-3294 Epistemic_statement denotes There was a statistically significant positive correlation between mortality and old age (r = 0.633), obesity (r = 0.712), diabetes mellitus (r = 0.685), renal failure (r = 0.705), chronic heart diseases (0.591), COPD (r = 0.523), malignancy (r = 0.692), kidney transplantation (r = 0.644) and liver cirrhosis (r = 0.525) (P < 0.05).
T10 3295-3427 Epistemic_statement denotes There was a statistically (P < 0.05) positive correlation between the number of associated co-morbidities and mortality (r = 0.735).
T11 3428-3538 Epistemic_statement denotes Conclusions: Most MERS corona patients present with fever, cough, dyspnea, sore throat, runny nose and sputum.
T12 4683-4818 Epistemic_statement denotes This work is done to determine the clinical characteristics and the outcome of ICU admitted patients with confirmed MERS-CoV infection.
T13 4974-5010 Epistemic_statement denotes All studied cases were subjected to:
T14 5011-5036 Epistemic_statement denotes (1) Full medical history.
T15 5392-5467 Epistemic_statement denotes (6) Arterial blood gases, including; PH, PaO 2 , SaO 2 , PaCO 2 and HCO 3 .
T16 5645-6042 Epistemic_statement denotes (8) Throat swab (Eurotubo, Deltalab, 08191 Rubı´, Barcelona, Spain), sputum, tracheal aspirate or bronchoalveolar lavage specimens were taken and stored at 28°C, and transported within 72 h to the reference laboratories, where they were subjected to real-time reverse-tran scriptase-polymerase-chain-reaction (rRT-PCR) assays to test for MERS-CoV (Altona Diagnostics GmbH, 22767 Hamburg, Germany).
T17 6417-6478 Epistemic_statement denotes Values of P < 0.05 were considered statistically significant.
T18 6548-6585 Epistemic_statement denotes The mean age was 43.99 ± 13.03 years.
T19 6920-7012 Epistemic_statement denotes The mean duration of symptoms before seeking medical advice was 5.30 ± 3.25 days (Table 1) .
T20 7251-7387 Epistemic_statement denotes Pneumothorax occurred in 5 (15.63%) ventilated patients, for 3 of them it was unilateral and for other 2 patients bilateral ( Table 1) .
T21 7388-7599 Epistemic_statement denotes Regarding the ABGs findings in our study: mean PH: 7.26 ± 0.33, mean PaO 2 : 64.04 ± 20.50 mmHg, mean O 2 saturation: 83.92 ± 17.45, mean PaCO 2 : 38.75 ± 4.17 mmHg, and mean HCO 3 19.44 ± 8.5 meq/L ( Table 1 ).
T22 7600-7720 Epistemic_statement denotes The mean APACHE II score was 22.46 ± 4.01, the mean SOFA score was 7.15 ± 2.85 and mean CPIS was 8.03 ± 1.35 (Table 1) .
T23 7926-8014 Epistemic_statement denotes All patients were admitted in ICU and a mean duration of ICU stay was 11.32 ± 4.50 days.
T24 8015-8152 Epistemic_statement denotes Regarding mechanical ventilation need, there were 23 (71.87%) ventilated patients and 9 (28.13%) patients without mechanical ventilation.
T25 13753-13967 Epistemic_statement denotes The duration of symptoms before hospitalization, ICU stay, mechanical ventilation and hospital stay in our studied patients were statistically significantly prolonged in the expired group compared to the survivors.
T26 15335-15425 Epistemic_statement denotes Our findings agree with other investigators who detected similar results [7] [8] [9] 15] .
T27 15895-15950 Epistemic_statement denotes Our results are in accordance with that of Reyes et al.
T28 16244-16379 Epistemic_statement denotes Non smoking and ex smoking were statistically significantly (P < 0.01) higher among the survivors in comparison with the expired group.
T29 17126-17132 Epistemic_statement denotes [17] .
T30 17133-17253 Epistemic_statement denotes Smoking increases CD8+ lymphocytes in the cell mediated system and suppresses the host defense against infections [18] .
T31 17576-17675 Epistemic_statement denotes Obesity can impede pulmonary function (reduced functional residual capacity and expiratory volume).
T32 18010-18105 Epistemic_statement denotes Obese persons are at an increased risk of developing pulmonary emboli and aspiration pneumonia.
T33 18894-18994 Epistemic_statement denotes Our results are in accordance with other workers' results [6] [7] [8] [9] [10] [11] [12] [13] [14] .
T34 19014-19199 Epistemic_statement denotes [25] concluded that people with DM, renal failure, and chronic lung disease and immuno-compromised persons are considered to be at a high risk of severe disease from MERS CoV infection.
T35 19513-19737 Epistemic_statement denotes Immuno-compromised patients have an increased attention because of the documentation of prolonged viral shedding in critically ill patients, with the subsequent emergence of resistance to neuraminidase inhibitor drugs [28] .
T36 20106-20603 Epistemic_statement denotes [30] concluded that the infectious diseases are more frequent and/or serious in patients with DM, which potentially increases their morbidity and mortality due to many factors as a deficiency of the C4 component in DM, this reduction of C4 is probably associated with polymorphonuclear dysfunction and reduced cytokine response decrease secretion of inflammatory cytokines as interleukin-1 (IL-1) and IL-6 decreased mobilization of polymorphonuclear leukocytes, chemotaxis and phagocytic activity.
T37 21103-21406 Epistemic_statement denotes Also, old age, current smoking, smoking severity, presence of associated co-morbidities like obesity, diabetes mellitus, chronic heart diseases, COPD, malignancy, renal failure, renal transplantation and liver cirrhosis associated with a poor outcome of ICU admitted MERS corona virus infected patients.