Epistemic_Statements  

CORD-19:4c04431830f520a349d5535bb15326c2553207b9 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 1083-1212 Epistemic_statement denotes These results suggest that there may be at least 6 different epitopes involved in NT reaction on the virion of the T0-163 strain.
T2 1404-1553 Epistemic_statement denotes Minor strain differences between TGE viruses have been shown by neutralization tests with polyclonal antibodies (Harada et al., 1967; Kemeny, 1976) .
T3 11421-11665 Epistemic_statement denotes Based on these results the seven virus strains could be classified into four groups: the TO-163, h-5 and Kanagawa strains in Group I, the Purdue strain in Group II, the Ukiha strain in Group III, and the Shizuoka and Miller strains in Group IV.
T4 11666-11842 Epistemic_statement denotes MC antibodies 4-4, 55-2 and 38-A, demonstrated NT activity to all of the virus strains tested, although the 38-A antibody showed low titers compared with those of 4-4 and 55-2.
T5 12374-12542 Epistemic_statement denotes The polyclonal antiserum to the TO-163 strain prepared in a pig showed essentially the same NT titers to all the virus strains and could not differentiate between them.
T6 14365-14479 Epistemic_statement denotes The epitopes recognized by our panel of MC antibodies with NT activity may also be present on E2 peplomer protein.
T7 14480-14581 Epistemic_statement denotes MC antibodies reacting in ELISA but having no NT activity may recognize epitopes on N or E1 proteins.
T8 14582-14726 Epistemic_statement denotes Further studies are required to elucidate the epitopes for these MC antibodies by Western immunoblotting, immunoprecipitation and other methods.
T9 14986-15146 Epistemic_statement denotes The results of NT tests on the seven TGE strains (Table II) suggest that there may be at least six NT-mediating determinants on the virion of the TO-163 strain.
T10 16661-16799 Epistemic_statement denotes This finding suggests that subunit vaccines containing E2 protein of the TO-163 strain may have protective efficacy against other strains.
T11 16800-16872 Epistemic_statement denotes MC antibodies 4-4 and 55-2 may be useful for purification of E2 protein.