CORD-19:3c1f47a07aaf0e393dee9fbd08596a4b9f4f0a03 / 81360-81780 5 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T159 | 0-420 | Epistemic_statement | denotes | Chloramphenicol's loss of favour began in the 1960s, when it was shown to have two distinct toxic effects on hematopoiesis: a frequently observed, dose-dependent anaemia, reversible on cessation of therapy, and an irreversible, 'idiosyncratic' aplastic anaemia, which had an incidence of approximately 1 case per 30,000 courses of therapy, a high case fatality rate, and no correlation with the or duration of treatment. |