Epistemic_Statements  

CORD-19:0a04d377a83b28dbc0d97c90acd829255796f69c JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 829-924 Epistemic_statement denotes Recent studies have demonstrated that there will not be a match between tumors of two patients.
T2 925-1026 Epistemic_statement denotes It implies that the scientists should work on medicines that are tailored to cure a specific patient.
T3 1027-1215 Epistemic_statement denotes Platinum based drugs are actively used in treating various types of cancers; however, drug resistance, adverse side effects and low specificity are common in platinum chemotherapy [3, 4] .
T4 1372-1534 Epistemic_statement denotes Important ones are the coordination compounds of Ni(II), Cu(II), Zn(II) and Ru(II) which can overcome the limited activity of cisplatin and its analogous [6, 7] .
T5 1535-1654 Epistemic_statement denotes Our current research puts in effort to crack a new anticancer drug candidate which could prove to be a better medicine.
T6 1926-2064 Epistemic_statement denotes They can easily form stable complexes with transition metal ions and can exhibit interesting photophysical and biological properties [8] .
T7 2231-2333 Epistemic_statement denotes Fluorenone is no doubt a polycyclic aromatic compound, one could doubt about its therapeutic property.
T8 2710-2982 Epistemic_statement denotes Our previous publication [17] have successfully established the anticancer efficacy of copper complex of fluorenone based ligand; which exhibited better anticancer activity against human breast carcinoma (MCF-7) cell line when compared to that of standard drug paclitaxel.
T9 5261-5302 Epistemic_statement denotes The contents are partially soluble at RT.
T10 8993-9212 Epistemic_statement denotes Automated molecular docking was carried out to determine the best orientation of the newly synthesized compounds possessing anti-cancer property was hypothesized as inhibitors bound in the active site of BCL-XL protein.
T11 10967-11181 Epistemic_statement denotes Simultaneously, two new bands have appeared in the range of 1520-1580 cm -1 and 1370-1380 cm -1 which are assigned to the asymmetric and symmetric stretching frequencies of coordinated carboxylate ion respectively.
T12 11348-11461 Epistemic_statement denotes Proton attached to carboxylic acid oxygen sometimes due to exchange with moisture in the solvent will not appear.
T13 11545-11629 Epistemic_statement denotes Remaining protons are aromatic and appeared as multiplets between 7.0-9.0 ppm [31] .
T14 12774-12886 Epistemic_statement denotes The IC 50 value of L 1 H, Cu(L 1 ) 2 , Cu(L 2 ) 2 , Ni(L 1 ) 2 and Ni(L 2 ) 2 compounds is found to be less than
T15 12887-12973 Epistemic_statement denotes 10µgmL -1 and other tested drugs also demonstrated very promising activity (Table 7) .
T16 13666-13782 Epistemic_statement denotes Designing small molecules help in targeting specific sites on a DNA strand and can lead to novel therapeutic agents.
T17 14059-14199 Epistemic_statement denotes Overall findings have revealed that the tested compounds can successfully cleave the DNA as it is evident from the images reproduced in Fig.