Epistemic_Statements  

CORD-19:00338998429de60726e4fe2dc07afaf65ed6f925 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 706-878 Epistemic_statement denotes Limited serologic testing (immunofluorescence assay, IFA) has provided some evidence that the disease may be linked to Ehrlichia risticii, the agent of Potomac horse fever.
T2 879-1140 Epistemic_statement denotes 1,a Owing to the remarkably high false-positive rate of the E. risticii IFA, 4 however, as well as an absence of confirmatory findings (e.g., isolation or detection of the causative agent), the etiology of this seasonally-recurring illness has remained unclear.
T3 1468-1588 Epistemic_statement denotes Sequencing results further indicated that the SRC agent is most closely related to the Kentucky strain s of E. risticii.
T4 4675-4740 Epistemic_statement denotes Shasta horse was most closely related to the Kentucky strain ofE.
T5 5207-5475 Epistemic_statement denotes Similarly, laminitis is a significant complication in a percentage of cases, s,l~ Interestingly, the gradual spread of SRC farther away from the river as the season progresses is an exact echo of the initial descriptions of Potomac horse fever along the Potomac River.
T6 5476-5739 Epistemic_statement denotes 8 Horses with SRC are indistinguishable clinically from Potomac horse fever cases we have identified in nearby Klamath Falls in southern Oregon, a where the disease is known locally as "ditch fever" from its association with pastures bordering irrigation ditches.
T7 6005-6197 Epistemic_statement denotes 11 Although the vector of E. risticii remains unidentifiedfl ~ it seems reasonable to suspect that if it is present in Klamath Falls, it may be present in Siskiyou and Shasta counties as well.
T8 6198-6342 Epistemic_statement denotes Available data suggest that the vector is not a tick, but is instead an organism closely associated in some way with river and irrigation water.
T9 6904-7126 Epistemic_statement denotes 5,13 It has been suggested that the degree of divergence shown by the Kentucky and Ohio 081 strains from E. risticii-Illinois may justify their removal from the species risticii and reassignment to separate species status.
T10 7127-7256 Epistemic_statement denotes 5 Thus it is possible that Potomac horse fever (and thus SRC) may be caused by more than a single species of the genus Ehrlichia.
T11 7257-7522 Epistemic_statement denotes Isolation and cultivation of various strains of E. risticii from different areas of the country should improve our understanding of the genetic and antigenic divergence of the organism, and aid in the development of more effective vaccines and serodiagnostic tests.
T12 7716-7984 Epistemic_statement denotes This part of California may be one of the few areas of the state where conditions necessary for the propagation and transmission of E. risticii and its reservoir hosts/vectors exist; overall the occurrence of Potomac horse fever in California horses appears to be low.
T13 7985-8181 Epistemic_statement denotes 4 Considering that SRC has been recognized in the region for at least 25 years, its clinical discovery appears to predate that of Potomac horse fever itself, which was first reported only in 1979.
T14 8182-8352 Epistemic_statement denotes 6 It is thus interesting to reflect how, but for the vicissitudes of history, the disease caused by E. risticii might just as easily have been named "Shasta horse fever."