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DisGeNet-2017-sample
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DisGeNet-2017-sample
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PubMed
25213700
Esophageal cancer stem cells express PLGF to increase cancer invasion through MMP9 activation. Cancer stem cells (CSCs) are a distinct population in tumors and cause cancer relapse and metastasis. Thu
1.49 KB
2016-01-20
7
23
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PubMed
24929024
Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers. Urothelial carcinoma of the bladder is the most frequent tumor of the urinary tra
1.7 KB
2016-01-17
8
11
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PubMed
20857420
Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1α translational pathway in colorectal cancer cells. Deep vein thrombosis associated with advanced cancer is kno
1.8 KB
2015-11-25
9
21
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PubMed
24164897
Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells. The Ras-extracellular signal-
1.41 KB
2015-11-27
10
7
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PubMed
19840121
Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2. BACE2 is homologous to BACE1, a beta-secretase that is involved in the amyloidogenic path
1.02 KB
2015-11-25
8
4
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PubMed
20470445
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. BACKGROUND: The orally active quinoline-3-carboxamide
1.85 KB
2015-11-25
9
12
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PubMed
8630377
Multiple tumor-suppressor gene 1 inactivation is the most frequent genetic alteration in T-cell acute lymphoblastic leukemia. No constant genetic alteration has yet been unravelled in T-cell acute lym
2.01 KB
2015-11-27
8
7
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PubMed
12002902
Screening for mutations in exons encoding the ligand-binding domain of the LDL receptor gene using PCR-CFLP and PCR-SSCP. Primary hypercholesterolemia includes both monogenic disorders and polygenic c
1.35 KB
2015-11-17
8
12
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PubMed
24088574
The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia. BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common p
1.32 KB
2015-11-26
10
4
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PubMed
26505133
Metformin synergistically sensitizes FLT3-ITD-positive acute myeloid leukemia to sorafenib by promoting mTOR-mediated apoptosis and autophagy. Mutations of Fms-like tyrosine kinase 3-internal tandem d
1.25 KB
2016-01-25
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