PubMed:17003357 27 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 17003357-0#34#40#gene26191 | 808-860 | gene26191 | denotes | P < 0.05). Sequencing of the coding region of PTPN22 |
| 17003357-0#50#65#diseaseC0011854 | 970-1276 | diseaseC0011854 | denotes | titution. Analysis of PTPN22 transcripts from a subject heterozygous for this variant indicated that it interfered with normal mRNA splicing, resulting in a premature termination codon after exon 17. These results support the conclusion that the 1858C/T allele is the major risk variant for type 1 diabetes |
| 34#40#gene2619150#65#diseaseC0011854 | 17003357-0#34#40#gene26191 | 17003357-0#50#65#diseaseC0011854 | associated_with | P < 0.05). Sequencing of the coding region of PTPN22,"titution. Analysis of PTPN22 transcripts from a subject heterozygous for this variant indicated that it interfered with normal mRNA splicing, resulting in a premature termination codon after exon 17. These results support the conclusion that the 1858C/T allele is the major risk variant for type 1 diabetes" |