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DisGeNET
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PubMed
16574813
Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway. The simple ganglioside GM3 has
2.21 KB
2019-05-30
68
3
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PubMed
15604091
Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism. Aberrant glycosylation of mucins is a common phenomenon associated with oncogenic transfo
1.4 KB
2019-05-30
67
12
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PubMed
15814824
Sequence-variant repeats of MUC1 show higher conformational flexibility, are less densely O-glycosylated and induce differential B lymphocyte responses. The human epithelial cancer mucin MUC1 is able
1.8 KB
2019-05-30
67
18
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PubMed
16037491
Patients with unsolved congenital disorders of glycosylation type II can be subdivided in six distinct biochemical groups. Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoele
1.88 KB
2019-05-30
67
18
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PubMed
18757779
Identification and characterization of the human Gb3/CD77 synthase gene promoter. Hemolytic uremic syndrome (HUS) is triggered by verotoxin (VT) produced by the Escherichia coli O157 strain. Several s
1.67 KB
2019-05-30
67
3
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PubMed
7949657
Expression of fucosylated antigens and alpha 1,3 fucosyltransferases in human leukaemia cell lines. The expression of alpha 1,3 fucosylated type 2 antigens is generally thought to be restricted to mye
2.58 KB
2019-05-30
67
3
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PubMed
9134429
Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection. Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carc
1.44 KB
2019-05-30
67
3
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PubMed
9884405
Expression of polypeptide GalNAc-transferases in stratified epithelia and squamous cell carcinomas: immunohistological evaluation using monoclonal antibodies to three members of the GalNAc-transferase
1.91 KB
2019-05-30
67
3
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PubMed
16449349
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination. In cancer, mucins are aberrantly O-glycosylated, and consequently, they express tumor-associated antigens such as
1.94 KB
2019-05-30
66
3
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PubMed
18316341
The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene. Ganglioside GM3 inhibits the growth of several cancer cells and induces cel
1.88 KB
2019-05-30
65
12
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