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PMC:3585731 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T422 4-13 Regulation denotes Regulates
T410 14-18 Protein denotes TNFα
T420 19-28 Gene_expression denotes Synthesis
T411 43-47 Protein denotes RIP1
T421 55-65 Positive_regulation denotes Activation
T412 443-473 Protein denotes receptor interacting protein-1
T413 475-479 Protein denotes RIP1
T424 580-584 Regulation denotes role
T414 588-592 Protein denotes TNFα
T423 593-603 Gene_expression denotes production
T415 647-651 Protein denotes RIP1
T425 740-748 Positive_regulation denotes requires
T416 807-811 Protein denotes RIP1
T417 973-977 Protein denotes RIP1
T418 1024-1028 Protein denotes TNFα
T427 1126-1148 Positive_regulation denotes necroptosis-associated
T419 1149-1153 Protein denotes TNFα
T426 1154-1164 Gene_expression denotes production
T1869 2132-2136 Protein denotes RIP1
T1870 2141-2145 Protein denotes RIP3
T1871 2757-2761 Protein denotes RIP1
T1872 2766-2770 Protein denotes RIP3
T1873 2964-2968 Protein denotes RIP1
T1874 3015-3020 Protein denotes c-Jun
T1875 3180-3184 Protein denotes TNFα
T1888 3185-3194 Gene_expression denotes synthesis
T1889 3196-3206 Positive_regulation denotes activation
T1890 3231-3240 Positive_regulation denotes induction
T6540 3308-3312 Protein denotes RIP1
T1876 3308-3312 Protein denotes RIP1
T1877 3352-3356 Protein denotes TNFα
T1891 3357-3367 Gene_expression denotes production
T1878 3627-3634 Protein denotes insulin
T1879 4106-4113 Protein denotes insulin
T1880 4284-4288 Protein denotes RIP1
T1881 4472-4476 Protein denotes RIP1
T1893 4532-4541 Positive_regulation denotes activated
T15115 4550-4554 Protein denotes RIP1
T1882 4550-4554 Protein denotes RIP1
T15150 4555-4571 Regulation denotes kinase-dependent
T1894 4555-4571 Positive_regulation denotes kinase-dependent
T15149 4579-4594 Phosphorylation denotes phosphorylation
T1892 4579-4594 Phosphorylation denotes phosphorylation
T1883 4709-4711 Protein denotes S6
T1897 4712-4723 Positive_regulation denotes contributes
T1896 4731-4741 Positive_regulation denotes activation
T1884 4761-4765 Protein denotes TNFα
T1895 4766-4776 Gene_expression denotes production
T1885 4842-4846 Protein denotes RIP1
T1898 4862-4872 Positive_regulation denotes activation
T1886 4955-4959 Protein denotes FADD
T1899 4960-4969 Negative_regulation denotes deficient
T1901 5068-5072 Positive_regulation denotes link
T1887 5076-5080 Protein denotes TNFα
T1900 5081-5091 Gene_expression denotes production
T3974 5289-5319 Protein denotes Basic Fibroblast Growth Factor
T3975 5472-5476 Protein denotes TNFα
T4003 5502-5512 Negative_regulation denotes inhibition
T3976 5516-5525 Protein denotes caspase-8
T4004 5563-5572 Negative_regulation denotes knockdown
T4005 5949-5953 Negative_regulation denotes loss
T3977 5987-5996 Protein denotes caspase-8
T3978 6001-6005 Protein denotes FADD
T3979 6411-6420 Protein denotes caspase-8
T4006 6449-6460 Positive_regulation denotes inactivates
T3980 6461-6465 Protein denotes RIP1
T3981 6481-6500 Protein denotes RIP1 deubiquitinase
T3982 6501-6505 Protein denotes CYLD
T3983 6726-6730 Protein denotes bFGF
T3984 6920-6924 Protein denotes bFGF
T3985 6929-6934 Protein denotes IGF-1
T3986 6944-6947 Protein denotes EGF
T3987 7081-7085 Protein denotes bFGF
T3988 7142-7146 Protein denotes TNFα
T4007 7196-7203 Negative_regulation denotes absence
T3989 7278-7282 Protein denotes TNFα
T28694 7377-7381 Protein denotes bFGF
T28695 7386-7391 Protein denotes IGF-1
T28696 7471-7475 Protein denotes TNFα
T28697 8080-8084 Protein denotes TNFα
T4008 8294-8303 Negative_regulation denotes inhibitor
T3990 8307-8311 Protein denotes RIP1
T3991 8606-8610 Protein denotes TNFα
T3992 8707-8711 Protein denotes RIP1
T4009 8845-8849 Negative_regulation denotes loss
T3993 8853-8857 Protein denotes RIP1
T3994 8992-8996 Protein denotes TNFα
T3995 9046-9050 Protein denotes bFGF
T3996 9091-9095 Protein denotes RIP1
T4010 9106-9117 Regulation denotes responsible
T3997 9217-9221 Protein denotes bFGF
T3998 9319-9348 Protein denotes bFGF receptor tyrosine kinase
T4011 9349-9359 Negative_regulation denotes inhibitors
T4012 9405-9415 Negative_regulation denotes inhibition
T3999 9419-9423 Protein denotes bFGF
T4000 9544-9557 Protein denotes bFGF receptor
T4013 9558-9567 Negative_regulation denotes inhibitor
T4001 9590-9594 Protein denotes TNFα
T4002 9792-9796 Protein denotes bFGF
T6541 10595-10599 Protein denotes bFGF
T6542 10603-10608 Protein denotes IGF-1
T6543 10750-10754 Protein denotes TNFα
T6544 10870-10874 Protein denotes TNFα
T6545 11088-11092 Protein denotes TNFα
T6574 11093-11100 Positive_regulation denotes induced
T29122 11217-11221 Protein denotes TNFα
T29123 11268-11272 Protein denotes TNFα
T29128 11499-11510 Gene_expression denotes transfected
T29124 11516-11520 Protein denotes Akt1
T29125 11522-11526 Protein denotes Akt2
T29126 11532-11543 Protein denotes Akt3 siRNAs
T29127 11585-11589 Protein denotes TNFα
T6575 12035-12044 Negative_regulation denotes knockdown
T6546 12061-12065 Protein denotes Akt1
T6547 12070-12074 Protein denotes Akt2
T6576 12081-12087 Negative_regulation denotes siRNAs
T6548 12150-12154 Protein denotes TNFα
T6577 12169-12179 Gene_expression denotes expression
T6549 12183-12187 Protein denotes Akt3
T6550 12241-12251 Protein denotes Akt3 siRNA
T6551 12555-12559 Protein denotes TNFα
T6578 12713-12721 Positive_regulation denotes zVAD.fmk
T6552 12725-12729 Protein denotes TNFα
T6580 12977-12985 Positive_regulation denotes increase
T6579 12993-13008 Phosphorylation denotes phosphorylation
T6553 13021-13024 Protein denotes p46
T6554 13029-13032 Protein denotes p54
T6555 13073-13078 Protein denotes c-Jun
T29657 13220-13224 Protein denotes RIP1
T29663 13225-13241 Regulation denotes kinase-dependent
T29662 13242-13257 Phosphorylation denotes phosphorylation
T29658 13338-13342 Protein denotes TNFα
T29659 13460-13464 Protein denotes bFGF
T29660 13624-13628 Protein denotes bFGF
T29661 13632-13636 Protein denotes bFGF
T6556 13745-13749 Protein denotes RIP1
T6581 13757-13766 Negative_regulation denotes inhibitor
T6584 13786-13795 Negative_regulation denotes prevented
T6583 13800-13808 Positive_regulation denotes increase
T6557 13819-13822 Protein denotes Akt
T6582 13823-13838 Phosphorylation denotes phosphorylation
T6558 14014-14018 Protein denotes TNFα
T6585 14046-14053 Regulation denotes changes
T6559 14089-14094 Protein denotes c-Jun
T6587 14158-14174 Positive_regulation denotes zVAD.fmk-induced
T6586 14175-14183 Positive_regulation denotes increase
T6560 14187-14192 Protein denotes c-Jun
T6561 14402-14406 Protein denotes RIP1
T6562 14698-14702 Protein denotes RIP1
T6588 14857-14865 Negative_regulation denotes addition
T6563 14869-14873 Protein denotes bFGF
T6589 14953-14961 Positive_regulation denotes increase
T6564 15030-15035 Protein denotes c-Jun
T6565 15158-15162 Protein denotes bFGF
T6566 15181-15185 Protein denotes bFGF
T6567 15453-15458 Protein denotes c-Jun
T6590 15459-15474 Phosphorylation denotes phosphorylation
T6591 15475-15484 Positive_regulation denotes triggered
T6568 15493-15497 Protein denotes bFGF
T6569 15502-15506 Protein denotes bFGF
T6593 15585-15592 Negative_regulation denotes blocked
T6570 15597-15601 Protein denotes bFGF
T6592 15607-15615 Positive_regulation denotes increase
T6571 15741-15745 Protein denotes RIP1
T6572 16165-16169 Protein denotes RIP1
T6573 16449-16453 Protein denotes RIP1
T7706 16463-16467 Protein denotes TNFα
T7707 16584-16588 Protein denotes TNFα
T7719 16589-16597 Positive_regulation denotes inducing
T7717 16598-16609 Negative_regulation denotes necroptosis
T7708 16687-16691 Protein denotes TNFα
T7718 16692-16699 Positive_regulation denotes induced
T7709 16843-16847 Protein denotes TNFα
T7710 16976-16980 Protein denotes TNFα
T7720 17048-17058 Positive_regulation denotes activation
T7711 17069-17073 Protein denotes TNFα
T7712 17133-17137 Protein denotes TNFα
T7722 17175-17183 Positive_regulation denotes increase
T7721 17191-17206 Phosphorylation denotes phosphorylation
T7713 17218-17223 Protein denotes c-Jun
T7716 17377-17381 Protein denotes RIP1
T7714 17476-17480 Protein denotes Ask1
T7715 17517-17521 Protein denotes RIP1
T8711 17690-17697 Positive_regulation denotes delayed
T8704 17698-17702 Protein denotes RIP1
T8712 17703-17719 Positive_regulation denotes kinase-dependent
T8709 17720-17728 Positive_regulation denotes increase
T8710 17772-17783 Positive_regulation denotes contributes
T8713 18234-18242 Positive_regulation denotes zVAD.fmk
T8705 18244-18248 Protein denotes TNFα
T8706 18252-18256 Protein denotes bFGF
T8707 18462-18466 Protein denotes bFGF
T8708 18501-18505 Protein denotes bFGF
T29958 19117-19121 Protein denotes bFGF
T29959 19237-19241 Protein denotes TNFα
T29960 19249-19253 Protein denotes bFGF
T29961 19503-19507 Protein denotes bFGF
T29962 19738-19742 Protein denotes bFGF
T10358 20088-20096 Positive_regulation denotes increase
T10357 20104-20119 Phosphorylation denotes phosphorylation
T10315 20216-20231 Protein denotes double minute 2
T10316 20233-20237 Protein denotes MDM2
T10317 20273-20304 Protein denotes p70 ribosomal protein S6 Kinase
T10318 20306-20312 Protein denotes p70S6K
T10319 20315-20317 Protein denotes S6
T10320 20345-20350 Protein denotes FoxO1
T10321 20352-20357 Protein denotes FoxO4
T10322 20359-20363 Protein denotes MDM2
T10327 20414-20420 Protein denotes FoxO3a
T10323 20422-20428 Protein denotes GSK-3α
T10324 20429-20430 Protein denotes β
T10325 20432-20438 Protein denotes p70S6K
T10326 20457-20459 Protein denotes S6
T10359 20484-20494 Positive_regulation denotes pronounced
T10328 20629-20635 Protein denotes pFoxO1
T10360 20772-20787 Phosphorylation denotes phosphorylation
T10329 21124-21128 Protein denotes RIP1
T30560 21290-21294 Protein denotes TNFα
T30561 21390-21394 Protein denotes bFGF
T30562 21398-21402 Protein denotes bFGF
T30563 21551-21555 Protein denotes TNFα
T30564 21764-21768 Protein denotes TNFα
T10361 22209-22218 Negative_regulation denotes inhibitor
T10330 22241-22247 Protein denotes Raptor
T10331 22616-22620 Protein denotes TNFα
T10362 22621-22628 Positive_regulation denotes induced
T10364 22653-22662 Regulation denotes regulates
T10363 22683-22693 Positive_regulation denotes activation
T10332 22697-22709 Protein denotes p70S6 kinase
T10333 22747-22749 Protein denotes S6
T10365 22912-22921 Negative_regulation denotes inhibitor
T10334 22925-22931 Protein denotes p70S6K
T10368 22993-23001 Positive_regulation denotes required
T10367 23005-23010 Negative_regulation denotes block
T10335 23011-23013 Protein denotes S6
T10366 23014-23029 Phosphorylation denotes phosphorylation
T10369 23059-23068 Negative_regulation denotes knockdown
T10336 23072-23074 Protein denotes S6
T10337 23167-23173 Protein denotes p70S6K
T10338 23174-23176 Protein denotes S6
T10339 23422-23426 Protein denotes RIP1
T10370 23467-23479 Positive_regulation denotes upregulation
T10340 23483-23487 Protein denotes TNFα
T10372 23635-23644 Positive_regulation denotes increased
T10371 23645-23654 Gene_expression denotes synthesis
T10341 23658-23662 Protein denotes TNFα
T10374 23747-23757 Positive_regulation denotes contribute
T10342 23761-23765 Protein denotes TNFα
T10373 23766-23775 Gene_expression denotes synthesis
T10343 23795-23799 Protein denotes RIP1
T10378 23800-23809 Regulation denotes dependent
T10375 23810-23818 Positive_regulation denotes increase
T10344 23822-23826 Protein denotes TNFα
T10345 23864-23868 Protein denotes TNFα
T10376 23874-23880 Transcription denotes levels
T10377 23881-23890 Positive_regulation denotes increased
T10346 23929-23933 Protein denotes RIP1
T10347 23974-23978 Protein denotes bFGF
T10380 23985-23994 Positive_regulation denotes triggered
T10379 24000-24009 Positive_regulation denotes induction
T10348 24013-24017 Protein denotes TNFα
T10384 24150-24156 Positive_regulation denotes caused
T10381 24166-24178 Positive_regulation denotes upregulation
T10349 24182-24186 Protein denotes TNFα
T10382 24215-24224 Positive_regulation denotes increased
T10385 24349-24357 Positive_regulation denotes increase
T10386 24361-24370 Positive_regulation denotes autocrine
T10350 24371-24375 Protein denotes TNFα
T10383 24376-24385 Gene_expression denotes synthesis
T30895 24454-24463 Positive_regulation denotes autocrine
T30886 24464-24468 Protein denotes TNFα
T30894 24469-24478 Gene_expression denotes synthesis
T30887 24574-24578 Protein denotes bFGF
T30888 24654-24659 Protein denotes mTNFα
T30889 24690-24693 Protein denotes 18S
T30890 24742-24746 Protein denotes TNFα
T30891 24848-24852 Protein denotes TNFα
T30896 24858-24864 Transcription denotes levels
T30892 24973-24977 Protein denotes TNFα
T30893 25020-25025 Protein denotes mTNFα
T10389 25146-25156 Positive_regulation denotes contribute
T10387 25164-25176 Positive_regulation denotes upregulation
T10351 25180-25184 Protein denotes TNFα
T10352 25287-25291 Protein denotes TNFα
T10388 25297-25303 Transcription denotes levels
T10353 25349-25353 Protein denotes RIP1
T10390 25362-25372 Negative_regulation denotes inhibitors
T10394 25380-25386 Regulation denotes effect
T10354 25404-25408 Protein denotes TNFα
T10391 25409-25413 Transcription denotes mRNA
T10392 25447-25457 Positive_regulation denotes stimulated
T10355 25463-25467 Protein denotes bFGF
T10396 25540-25547 Positive_regulation denotes mediate
T10397 25548-25569 Regulation denotes necroptosis-dependent
T10395 25570-25578 Positive_regulation denotes increase
T10356 25582-25586 Protein denotes TNFα
T10393 25587-25596 Gene_expression denotes synthesis
T12431 25689-25698 Regulation denotes regulator
T12418 25702-25706 Protein denotes TNFα
T12430 25707-25716 Gene_expression denotes synthesis
T12432 25830-25838 Positive_regulation denotes increase
T12419 25842-25846 Protein denotes TNFα
T12433 25927-25936 Negative_regulation denotes Knockdown
T12420 25953-25957 Protein denotes Akt1
T12421 25962-25966 Protein denotes Akt2
T12436 26000-26010 Negative_regulation denotes suppressed
T12438 26027-26036 Regulation denotes dependent
T12437 26037-26045 Positive_regulation denotes increase
T12422 26057-26062 Protein denotes c-Jun
T12434 26063-26078 Phosphorylation denotes phosphorylation
T12435 26130-26134 Binding denotes link
T12423 26143-26147 Protein denotes RIP1
T12441 26218-26225 Negative_regulation denotes delayed
T12439 26246-26254 Positive_regulation denotes increase
T12424 26258-26262 Protein denotes bFGF
T12442 26272-26279 Positive_regulation denotes induced
T12425 26288-26293 Protein denotes c-Jun
T12440 26294-26309 Phosphorylation denotes phosphorylation
T12443 26322-26331 Negative_regulation denotes Knockdown
T12427 26359-26365 Protein denotes p70S6K
T12444 26366-26375 Negative_regulation denotes inhibitor
T12447 26392-26402 Negative_regulation denotes attenuated
T12446 26430-26438 Positive_regulation denotes increase
T12426 26450-26455 Protein denotes c-Jun
T12445 26456-26471 Phosphorylation denotes phosphorylation
T12428 26550-26553 Protein denotes S6K
T12448 26560-26566 Positive_regulation denotes acting
T12429 26583-26587 Protein denotes RIP1
T13226 26691-26695 Protein denotes PDK1
T13233 27044-27058 Phosphorylation denotes phosphorylated
T13227 27083-27128 Protein denotes 3-phosphoinositide dependent protein kinase-1
T13228 27130-27134 Protein denotes PDK1
T13229 27333-27337 Protein denotes PDK1
T13234 27339-27349 Negative_regulation denotes Inhibition
T13230 27362-27366 Protein denotes PDK1
T13235 27421-27429 Positive_regulation denotes resulted
T13236 27533-27542 Negative_regulation denotes knockdown
T13231 27546-27550 Protein denotes PDK1
T13232 27652-27656 Protein denotes PDK1
T13237 27675-27683 Positive_regulation denotes required
T15144 27853-27863 Gene_expression denotes expressing
T15101 27896-27900 Protein denotes Akt1
T15102 27902-27909 Protein denotes Myr-Akt
T15103 27948-27953 Protein denotes K179M
T15104 28024-28028 Protein denotes RIP1
T15105 28096-28100 Protein denotes Akt1
T15106 28102-28109 Protein denotes Myr-Akt
T15145 28416-28426 Gene_expression denotes expressing
T15107 28427-28434 Protein denotes Myr-Akt
T15108 28713-28720 Protein denotes Myr-Akt
T15109 28734-28739 Protein denotes K179M
T15110 28826-28833 Protein denotes Myr-Akt
T15148 29008-29018 Positive_regulation denotes activation
T15111 29030-29035 Protein denotes c-Jun
T15146 29036-29051 Phosphorylation denotes phosphorylation
T15147 29066-29078 Positive_regulation denotes upregulation
T15112 29082-29086 Protein denotes TNFα
T15113 29384-29388 Protein denotes RIP1
T15114 29493-29497 Protein denotes RIP1
T31466 30397-30401 Protein denotes TNFα
T31469 30407-30413 Transcription denotes levels
T31467 30468-30471 Protein denotes 18S
T31468 30699-30703 Protein denotes TNFα
T31470 30709-30715 Transcription denotes levels
T15116 30828-30835 Protein denotes Myr-Akt
T15117 30865-30872 Protein denotes Myr-Akt
T15152 30986-30995 Positive_regulation denotes increased
T15151 31005-31015 Gene_expression denotes expression
T15118 31019-31026 Protein denotes Myr-Akt
T15119 31040-31045 Protein denotes K179M
T15153 31204-31213 Positive_regulation denotes increased
T15120 31232-31239 Protein denotes Myr-Akt
T15121 31268-31274 Protein denotes p70S6K
T15122 31276-31278 Protein denotes S6
T15123 31290-31295 Protein denotes FoxO4
T15154 31308-31322 Phosphorylation denotes phosphorylated
T15155 31375-31390 Phosphorylation denotes phosphorylation
T15124 31394-31399 Protein denotes FoxO1
T15125 31404-31408 Protein denotes MDM2
T15156 31427-31436 Positive_regulation denotes increased
T15157 31501-31516 Phosphorylation denotes phosphorylation
T15126 31520-31527 Protein denotes Myr-Akt
T15127 31653-31657 Protein denotes TNFα
T15158 31658-31668 Gene_expression denotes production
T15159 31697-31706 Gene_expression denotes expressed
T15128 31707-31714 Protein denotes Myr-Akt
T15160 32276-32285 Negative_regulation denotes reduction
T15129 32315-32318 Protein denotes Akt
T15130 32771-32783 Protein denotes S473D mutant
T15161 32795-32809 Phosphorylation denotes phosphorylated
T15131 32896-32901 Protein denotes S473A
T15132 32963-32968 Protein denotes S473A
T15162 32998-33012 Phosphorylation denotes phosphorylated
T15133 33133-33137 Protein denotes PDK1
T15163 33141-33154 Phosphorylation denotes phosphorylate
T15164 33249-33258 Positive_regulation denotes promoting
T15165 33271-33286 Phosphorylation denotes phosphorylation
T15134 33298-33303 Protein denotes c-Jun
T15135 33309-33313 Protein denotes TNFα
T15136 33339-33344 Protein denotes T308D
T15166 33419-33434 Phosphorylation denotes phosphorylation
T15137 33583-33588 Protein denotes T308D
T15167 33620-33635 Phosphorylation denotes phosphorylation
T15168 33668-33682 Phosphorylation denotes phosphorylated
T15138 33690-33697 Protein denotes Myr-Akt
T15139 33742-33747 Protein denotes FoxO1
T15140 33749-33754 Protein denotes Foxo4
T15141 33756-33760 Protein denotes MDM2
T15142 33766-33772 Protein denotes p70S6K
T15143 34012-34016 Protein denotes TNFα
T17858 34073-34081 Regulation denotes Controls
T17838 34082-34086 Protein denotes TNFα
T17857 34087-34097 Gene_expression denotes Production
T17839 34149-34153 Protein denotes RIP1
T17840 34303-34343 Protein denotes Fas-associated protein with death domain
T17841 34345-34349 Protein denotes FADD
T17842 34509-34513 Protein denotes TNFα
T17843 34571-34575 Protein denotes RIP1
T17844 34718-34722 Protein denotes TNFα
T17859 34728-34734 Transcription denotes levels
T17860 34740-34749 Positive_regulation denotes increased
T17862 34813-34822 Negative_regulation denotes inhibited
T17845 34831-34835 Protein denotes RIP1
T17861 34844-34854 Negative_regulation denotes inhibitors
T17864 34980-34990 Regulation denotes regulation
T17865 34994-35003 Positive_regulation denotes autocrine
T17847 35004-35008 Protein denotes TNFα
T17863 35009-35018 Gene_expression denotes synthesis
T17846 35131-35135 Protein denotes RIP1
T32170 35283-35292 Positive_regulation denotes autocrine
T32157 35293-35297 Protein denotes TNFα
T32169 35298-35308 Gene_expression denotes production
T32158 35333-35337 Protein denotes FADD
T32171 35338-35347 Negative_regulation denotes deficient
T32159 35379-35383 Protein denotes TNFα
T32160 35421-35425 Protein denotes TNFα
T32172 35431-35437 Transcription denotes levels
T32161 35476-35479 Protein denotes 18S
T32162 35631-35635 Protein denotes TNFα
T32173 35641-35647 Transcription denotes levels
T32163 35785-35789 Protein denotes TNFα
T32164 35817-35821 Protein denotes TNFα
T32174 35827-35833 Transcription denotes levels
T32175 35881-35891 Gene_expression denotes expressing
T32168 35908-35912 Protein denotes Akt1
T32165 35916-35920 Protein denotes Akt2
T32166 35952-35956 Protein denotes TNFα
T32167 35984-35988 Protein denotes TNFα
T32176 35994-36000 Transcription denotes levels
T17848 36243-36247 Protein denotes TNFα
T17867 36326-36334 Negative_regulation denotes restored
T17849 36335-36339 Protein denotes TNFα
T17866 36345-36355 Transcription denotes production
T17850 36371-36375 Protein denotes TNFα
T17868 36511-36521 Gene_expression denotes expressing
T17851 36533-36537 Protein denotes Akt1
T17852 36541-36545 Protein denotes Akt2
T17869 36551-36565 Phosphorylation denotes phosphorylated
T17853 36591-36595 Protein denotes TNFα
T17854 36645-36649 Protein denotes RIP1
T17871 36650-36659 Positive_regulation denotes dependent
T17855 36660-36664 Protein denotes TNFα
T17870 36670-36682 Positive_regulation denotes upregulation
T17856 36814-36818 Protein denotes TNFα
T17872 36819-36828 Gene_expression denotes synthesis
T19399 37024-37028 Protein denotes RIP1
T19400 37118-37122 Protein denotes RIP1
T19401 37374-37378 Protein denotes RIP1
T19425 37393-37398 Positive_regulation denotes leads
T19426 37686-37696 Gene_expression denotes Expression
T19402 37750-37757 Protein denotes Myr-Akt
T19427 37823-37833 Gene_expression denotes expression
T19403 37837-37844 Protein denotes Myr-Akt
T19428 37858-37868 Positive_regulation denotes sufficient
T19404 37913-37917 Protein denotes RIP1
T19429 37918-37934 Positive_regulation denotes kinase-dependent
T32427 38138-38142 Protein denotes RIP1
T32428 38297-38301 Protein denotes RIP1
T32431 38346-38351 Positive_regulation denotes leads
T32429 38355-38359 Protein denotes TNFα
T32430 38360-38369 Gene_expression denotes synthesis
T19430 39159-39169 Positive_regulation denotes connecting
T19405 39170-39174 Protein denotes RIP1
T19406 39297-39301 Protein denotes TNFα
T19431 39302-39311 Gene_expression denotes synthesis
T19433 39569-39578 Negative_regulation denotes inhibited
T19407 39579-39583 Protein denotes TNFα
T19432 39584-39594 Gene_expression denotes production
T19408 39820-39833 Protein denotes p110δ subunit
T19409 39851-39855 Protein denotes PDK1
T19410 40119-40123 Protein denotes JNK1
T19411 40128-40132 Protein denotes JNK2
T19412 40197-40201 Protein denotes JNK1
T19413 40202-40203 Protein denotes 2
T19434 40266-40281 Phosphorylation denotes phosphorylation
T19414 40285-40290 Protein denotes c-Jun
T19436 40371-40380 Negative_regulation denotes reduction
T19415 40384-40388 Protein denotes TNFα
T19435 40389-40399 Gene_expression denotes production
T19416 40627-40632 Protein denotes c-Jun
T19437 40652-40661 Positive_regulation denotes autocrine
T19417 40662-40666 Protein denotes TNFα
T19418 40735-40740 Protein denotes c-Jun
T19439 40741-40746 Negative_regulation denotes siRNA
T19438 40747-40756 Negative_regulation denotes knockdown
T19442 40872-40881 Positive_regulation denotes autocrine
T19419 40882-40886 Protein denotes TNFα
T19440 40887-40897 Gene_expression denotes production
T19441 40899-40908 Positive_regulation denotes dependent
T19420 40912-40917 Protein denotes c-Jun
T19443 41054-41062 Positive_regulation denotes increase
T19421 41087-41092 Protein denotes c-Jun
T19422 41140-41144 Protein denotes TNFα
T19423 41267-41272 Protein denotes c-Jun
T19444 41407-41422 Phosphorylation denotes phosphorylation
T19424 41426-41431 Protein denotes c-Jun
T22952 41723-41727 Protein denotes RIP1
T22953 41867-41871 Protein denotes RIP1
T22994 41984-41993 Positive_regulation denotes autocrine
T22954 41994-41998 Protein denotes TNFα
T22993 41999-42008 Gene_expression denotes synthesis
T22995 42215-42225 Gene_expression denotes Expression
T22996 42251-42268 Positive_regulation denotes membrane-targeted
T22955 42269-42276 Protein denotes Myr-Akt
T22997 42323-42333 Gene_expression denotes expression
T22956 42337-42344 Protein denotes Myr-Akt
T22998 42352-42362 Positive_regulation denotes sufficient
T23000 42409-42419 Positive_regulation denotes activation
T22957 42431-42435 Protein denotes TNFα
T22999 42436-42445 Gene_expression denotes synthesis
T22958 42457-42461 Protein denotes RIP1
T23001 42462-42478 Positive_regulation denotes kinase-dependent
T22959 43036-43040 Protein denotes RIP1
T22960 43115-43119 Protein denotes RIP1
T23002 43127-43135 Negative_regulation denotes inhibits
T22961 43486-43490 Protein denotes RIP1
T23003 43498-43507 Binding denotes targeting
T22962 43508-43512 Protein denotes PDK1
T23004 43607-43622 Phosphorylation denotes phosphorylation
T22963 43645-43649 Protein denotes RIP1
T23005 43728-43736 Negative_regulation denotes mutating
T22964 43762-43769 Protein denotes Myr-Akt
T23006 44068-44083 Phosphorylation denotes phosphorylation
T22965 44094-44098 Protein denotes RIP1
T23007 44170-44180 Regulation denotes regulation
T23009 44230-44237 Positive_regulation denotes promote
T22966 44257-44261 Protein denotes TNFα
T23008 44262-44271 Gene_expression denotes synthesis
T22967 44983-44987 Protein denotes TNFα
T23010 45096-45107 Positive_regulation denotes contributes
T22968 45130-45134 Protein denotes TNFα
T23011 45435-45445 Regulation denotes regulation
T22969 45456-45460 Protein denotes RIP1
T22970 45667-45672 Protein denotes FoxO1
T22971 45673-45674 Protein denotes 4
T22972 45680-45684 Protein denotes MDM2
T22973 46185-46189 Protein denotes RIP1
T23012 46198-46208 Gene_expression denotes expression
T22974 46851-46855 Protein denotes TNFα
T22975 46979-46983 Protein denotes TNFα
T22976 47343-47347 Protein denotes RIP1
T22977 47593-47597 Protein denotes FADD
T23013 47598-47607 Negative_regulation denotes deficient
T23015 47688-47696 Positive_regulation denotes increase
T22978 47700-47704 Protein denotes TNFα
T23014 47705-47714 Gene_expression denotes synthesis
T22979 47861-47865 Protein denotes RIP1
T23017 47893-47902 Positive_regulation denotes mediating
T23016 47907-47917 Gene_expression denotes production
T22980 47921-47925 Protein denotes TNFα
T23019 48673-48683 Positive_regulation denotes activation
T22981 48687-48691 Protein denotes TNFα
T23018 48692-48701 Gene_expression denotes synthesis
T22982 48705-48709 Protein denotes RIP1
T23020 48928-48932 Negative_regulation denotes loss
T22983 48949-48953 Protein denotes RIP1
T22984 48954-48958 Protein denotes RIP3
T22985 48980-48984 Protein denotes FADD
T22986 48989-48998 Protein denotes caspase-8
T22987 49069-49073 Protein denotes TNFα
T23021 49074-49084 Gene_expression denotes production
T23023 49213-49222 Positive_regulation denotes increased
T23022 49223-49233 Gene_expression denotes production
T22988 49237-49241 Protein denotes TNFα
T22989 49582-49586 Protein denotes RIP1
T22990 49591-49595 Protein denotes RIP3
T23024 49664-49668 Regulation denotes role
T22991 49672-49676 Protein denotes RIP1
T22992 49785-49789 Protein denotes RIP1
T23025 49797-49807 Negative_regulation denotes inhibitors
T25259 50802-50806 Protein denotes TNFα
T25260 50825-50829 Protein denotes bFGF
T25261 50842-50845 Protein denotes EGF
T25262 50882-50887 Protein denotes IGF-1
T25651 50989-50997 Protein denotes Myr-Akt1
T25652 51056-51069 Protein denotes Myr-Akt1-FLAG
T25653 51201-51209 Protein denotes Myr-Akt1
T26071 52217-52221 Protein denotes TNFα
T26072 52302-52305 Protein denotes 18S
T26073 52392-52396 Protein denotes TNFα
T26074 52443-52447 Protein denotes TNFα
T26075 52493-52496 Protein denotes 18S
T26076 52541-52544 Protein denotes 18S
T26328 52603-52607 Protein denotes FADD
T26329 52608-52617 Negative_regulation denotes deficient
T26875 54009-54013 Protein denotes Akt1
T26876 54035-54039 Protein denotes Akt2
T26877 54061-54065 Protein denotes Akt3
T26878 54113-54117 Protein denotes PDK1
T26879 54176-54181 Protein denotes Mapk8
T26880 54203-54208 Protein denotes Mapk9
T26881 54402-54406 Protein denotes TNFα
T27321 54647-54651 Protein denotes TNFα
T27322 54806-54810 Protein denotes TNFα
T27859 56096-56104 Protein denotes Myr-Akt1
T28223 57079-57083 Protein denotes TNFα
T28224 57096-57100 Protein denotes TNFα
T28376 57427-57434 Protein denotes Myr-Akt
T28377 57439-57457 Binding denotes immunoprecipitated
R11976 T17838 T17857 themeOf TNFα,Production
R11977 T17844 T17859 themeOf TNFα,levels
R11978 T17845 T17861 themeOf RIP1,inhibitors
R11979 T17847 T17863 themeOf TNFα,synthesis
R11980 T17849 T17866 themeOf TNFα,production
R11981 T17851 T17868 themeOf Akt1,expressing
R11982 T17852 T17868 themeOf Akt2,expressing
R11983 T17853 T17869 themeOf TNFα,phosphorylated
R11984 T17854 T17871 causeOf RIP1,dependent
R11985 T17855 T17870 themeOf TNFα,upregulation
R11986 T17856 T17872 themeOf TNFα,synthesis
R11987 T17857 T17858 themeOf Production,Controls
R11988 T17859 T17860 themeOf levels,increased
R11989 T17859 T17862 themeOf levels,inhibited
R11990 T17861 T17862 causeOf inhibitors,inhibited
R11991 T17863 T17864 themeOf synthesis,regulation
R11992 T17863 T17865 themeOf synthesis,autocrine
R11993 T17865 T17864 themeOf autocrine,regulation
R11994 T17866 T17867 themeOf production,restored
R11995 T17870 T17871 themeOf upregulation,dependent
R1216 T1875 T1888 themeOf TNFα,synthesis
R1217 T1877 T1891 themeOf TNFα,production
R1218 T1882 T1892 themeOf RIP1,phosphorylation
R1219 T1884 T1895 themeOf TNFα,production
R1220 T1885 T1898 themeOf RIP1,activation
R1221 T1886 T1899 themeOf FADD,deficient
R1222 T1887 T1900 themeOf TNFα,production
R1223 T1888 T1889 themeOf synthesis,activation
R1224 T1888 T1890 themeOf synthesis,induction
R1225 T1892 T1893 themeOf phosphorylation,activated
R1226 T1892 T1894 themeOf phosphorylation,kinase-dependent
R1227 T1895 T1896 themeOf production,activation
R1228 T1896 T1897 themeOf activation,contributes
R1229 T1900 T1901 themeOf production,link
R12932 T19401 T19425 themeOf RIP1,leads
R12933 T19402 T19426 themeOf Myr-Akt,Expression
R12934 T19403 T19427 themeOf Myr-Akt,expression
R12935 T19404 T19429 themeOf RIP1,kinase-dependent
R12936 T19405 T19430 themeOf RIP1,connecting
R12937 T19406 T19431 themeOf TNFα,synthesis
R12938 T19407 T19432 themeOf TNFα,production
R12939 T19414 T19434 themeOf c-Jun,phosphorylation
R12940 T19415 T19435 themeOf TNFα,production
R12941 T19417 T19437 themeOf TNFα,autocrine
R12942 T19418 T19438 themeOf c-Jun,knockdown
R12943 T19419 T19440 themeOf TNFα,production
R12944 T19420 T19441 causeOf c-Jun,dependent
R12945 T19421 T19443 themeOf c-Jun,increase
R12946 T19424 T19444 themeOf c-Jun,phosphorylation
R12947 T19427 T19428 themeOf expression,sufficient
R12948 T19432 T19433 themeOf production,inhibited
R12949 T19435 T19436 themeOf production,reduction
R12950 T19438 T19439 themeOf knockdown,siRNA
R12951 T19439 T19438 themeOf siRNA,knockdown
R12952 T19440 T19441 themeOf production,dependent
R12953 T19440 T19442 themeOf production,autocrine
R15406 T22954 T22993 themeOf TNFα,synthesis
R15407 T22955 T22995 themeOf Myr-Akt,Expression
R15408 T22955 T22996 themeOf Myr-Akt,membrane-targeted
R15409 T22956 T22997 themeOf Myr-Akt,expression
R15410 T22957 T22999 themeOf TNFα,synthesis
R15411 T22958 T23001 themeOf RIP1,kinase-dependent
R15412 T22960 T23002 themeOf RIP1,inhibits
R15413 T22961 T23003 themeOf RIP1,targeting
R15414 T22962 T23003 themeOf PDK1,targeting
R15415 T22963 T23004 themeOf RIP1,phosphorylation
R15416 T22964 T23005 themeOf Myr-Akt,mutating
R15417 T22965 T23006 themeOf RIP1,phosphorylation
R15418 T22966 T23008 themeOf TNFα,synthesis
R15419 T22968 T23010 themeOf TNFα,contributes
R15420 T22969 T23011 themeOf RIP1,regulation
R15421 T22973 T23012 themeOf RIP1,expression
R15422 T22977 T23013 themeOf FADD,deficient
R15423 T22978 T23014 themeOf TNFα,synthesis
R15424 T22979 T23017 causeOf RIP1,mediating
R15425 T22980 T23016 themeOf TNFα,production
R15426 T22981 T23018 themeOf TNFα,synthesis
R15427 T22985 T23020 themeOf FADD,loss
R15428 T22986 T23020 themeOf caspase-8,loss
R15429 T22987 T23021 themeOf TNFα,production
R15430 T22988 T23022 themeOf TNFα,production
R15431 T22991 T23024 themeOf RIP1,role
R15432 T22992 T23025 themeOf RIP1,inhibitors
R15433 T22993 T22994 themeOf synthesis,autocrine
R15434 T22995 T22996 themeOf Expression,membrane-targeted
R15435 T22997 T22998 themeOf expression,sufficient
R15436 T22999 T23000 themeOf synthesis,activation
R15437 T23006 T23007 themeOf phosphorylation,regulation
R15438 T23008 T23009 themeOf synthesis,promote
R15439 T23014 T23015 themeOf synthesis,increase
R15440 T23016 T23017 themeOf production,mediating
R15441 T23018 T23019 themeOf synthesis,activation
R15442 T23022 T23023 themeOf production,increased
R18020 T26328 T26329 themeOf FADD,deficient
R19679 T28376 T28377 themeOf Myr-Akt,immunoprecipitated
R20185 T29124 T29128 themeOf Akt1,transfected
R20186 T29125 T29128 themeOf Akt2,transfected
R20187 T29126 T29128 themeOf Akt3 siRNAs,transfected
R20564 T29657 T29662 themeOf RIP1,phosphorylation
R20565 T29662 T29663 themeOf phosphorylation,kinase-dependent
R211 T426 T427 themeOf production,necroptosis-associated
R21356 T30886 T30894 themeOf TNFα,synthesis
R21357 T30891 T30896 themeOf TNFα,levels
R21358 T30894 T30895 themeOf synthesis,autocrine
R21762 T31466 T31469 themeOf TNFα,levels
R21763 T31468 T31470 themeOf TNFα,levels
R22227 T32157 T32169 themeOf TNFα,production
R22228 T32158 T32171 themeOf FADD,deficient
R22229 T32160 T32172 themeOf TNFα,levels
R22230 T32162 T32173 themeOf TNFα,levels
R22231 T32164 T32174 themeOf TNFα,levels
R22232 T32165 T32175 themeOf Akt2,expressing
R22233 T32167 T32176 themeOf TNFα,levels
R22234 T32168 T32175 themeOf Akt1,expressing
R22235 T32169 T32170 themeOf production,autocrine
R22325 T32429 T32430 themeOf TNFα,synthesis
R22326 T32430 T32431 themeOf synthesis,leads
R2725 T3976 T4003 themeOf caspase-8,inhibition
R2726 T3977 T4005 themeOf caspase-8,loss
R2727 T3978 T4005 themeOf FADD,loss
R2728 T3980 T4006 themeOf RIP1,inactivates
R2729 T3981 T4006 themeOf RIP1 deubiquitinase,inactivates
R2730 T3982 T4006 themeOf CYLD,inactivates
R2731 T3988 T4007 themeOf TNFα,absence
R2732 T3990 T4008 themeOf RIP1,inhibitor
R2733 T3993 T4009 themeOf RIP1,loss
R2734 T3996 T4010 themeOf RIP1,responsible
R2735 T3998 T4011 themeOf bFGF receptor tyrosine kinase,inhibitors
R2736 T3999 T4012 themeOf bFGF,inhibition
R2737 T4000 T4013 themeOf bFGF receptor,inhibitor
R2738 T4003 T4004 themeOf inhibition,knockdown
R4422 T6545 T6574 themeOf TNFα,induced
R4423 T6546 T6575 themeOf Akt1,knockdown
R4424 T6546 T6576 themeOf Akt1,siRNAs
R4425 T6547 T6575 themeOf Akt2,knockdown
R4426 T6547 T6576 themeOf Akt2,siRNAs
R4427 T6549 T6577 themeOf Akt3,expression
R4428 T6552 T6578 themeOf TNFα,zVAD.fmk
R4429 T6553 T6579 themeOf p46,phosphorylation
R4430 T6554 T6579 themeOf p54,phosphorylation
R4431 T6555 T6579 themeOf c-Jun,phosphorylation
R4432 T6556 T6581 themeOf RIP1,inhibitor
R4433 T6557 T6582 themeOf Akt,phosphorylation
R4434 T6559 T6585 themeOf c-Jun,changes
R4435 T6560 T6586 themeOf c-Jun,increase
R4436 T6563 T6588 themeOf bFGF,addition
R4437 T6564 T6589 themeOf c-Jun,increase
R4438 T6567 T6590 themeOf c-Jun,phosphorylation
R4439 T6568 T6591 themeOf bFGF,triggered
R4440 T6569 T6591 causeOf bFGF,triggered
R4441 T6570 T6592 themeOf bFGF,increase
R4442 T6576 T6575 themeOf siRNAs,knockdown
R4443 T6576 T6575 themeOf siRNAs,knockdown
R4444 T6579 T6580 themeOf phosphorylation,increase
R4445 T6579 T6580 themeOf phosphorylation,increase
R4446 T6579 T6580 themeOf phosphorylation,increase
R4447 T6581 T6584 causeOf inhibitor,prevented
R4448 T6582 T6583 themeOf phosphorylation,increase
R4449 T6583 T6584 themeOf increase,prevented
R4450 T6586 T6587 themeOf increase,zVAD.fmk-induced
R4451 T6587 T6586 themeOf zVAD.fmk-induced,increase
R4452 T6592 T6593 themeOf increase,blocked
R457 T410 T420 themeOf TNFα,Synthesis
R458 T411 T421 themeOf RIP1,Activation
R459 T414 T423 themeOf TNFα,production
R460 T416 T425 themeOf RIP1,requires
R461 T419 T426 themeOf TNFα,production
R462 T420 T422 themeOf Synthesis,Regulates
R463 T423 T424 themeOf production,role
R4991 T7707 T7717 themeOf TNFα,necroptosis
R4992 T7708 T7718 themeOf TNFα,induced
R4993 T7711 T7720 themeOf TNFα,activation
R4994 T7713 T7721 themeOf c-Jun,phosphorylation
R4995 T7717 T7719 themeOf necroptosis,inducing
R4996 T7719 T7717 themeOf inducing,necroptosis
R4997 T7721 T7722 themeOf phosphorylation,increase
R5728 T8704 T8709 themeOf RIP1,increase
R5729 T8705 T8713 themeOf TNFα,zVAD.fmk
R5730 T8706 T8713 themeOf bFGF,zVAD.fmk
R5731 T8709 T8710 themeOf increase,contributes
R5732 T8709 T8711 themeOf increase,delayed
R5733 T8709 T8712 themeOf increase,kinase-dependent
R5734 T8711 T8709 themeOf delayed,increase
R6701 T10315 T10357 themeOf double minute 2,phosphorylation
R6702 T10316 T10357 themeOf MDM2,phosphorylation
R6703 T10317 T10357 themeOf p70 ribosomal protein S6 Kinase,phosphorylation
R6704 T10318 T10357 themeOf p70S6K,phosphorylation
R6705 T10319 T10357 themeOf S6,phosphorylation
R6706 T10323 T10359 themeOf GSK-3α,pronounced
R6707 T10324 T10359 themeOf β,pronounced
R6708 T10325 T10359 themeOf p70S6K,pronounced
R6709 T10326 T10359 themeOf S6,pronounced
R6710 T10327 T10359 themeOf FoxO3a,pronounced
R6711 T10328 T10360 themeOf pFoxO1,phosphorylation
R6712 T10330 T10361 themeOf Raptor,inhibitor
R6713 T10331 T10362 themeOf TNFα,induced
R6714 T10332 T10363 themeOf p70S6 kinase,activation
R6715 T10333 T10364 causeOf S6,regulates
R6716 T10334 T10365 themeOf p70S6K,inhibitor
R6717 T10335 T10366 themeOf S6,phosphorylation
R6718 T10336 T10369 themeOf S6,knockdown
R6719 T10340 T10370 themeOf TNFα,upregulation
R6720 T10341 T10371 themeOf TNFα,synthesis
R6721 T10342 T10373 themeOf TNFα,synthesis
R6722 T10343 T10378 causeOf RIP1,dependent
R6723 T10344 T10375 themeOf TNFα,increase
R6724 T10345 T10376 themeOf TNFα,levels
R6725 T10346 T10377 themeOf RIP1,increased
R6726 T10347 T10380 causeOf bFGF,triggered
R6727 T10348 T10379 themeOf TNFα,induction
R6728 T10349 T10381 themeOf TNFα,upregulation
R6729 T10350 T10383 themeOf TNFα,synthesis
R6730 T10351 T10387 themeOf TNFα,upregulation
R6731 T10352 T10388 themeOf TNFα,levels
R6732 T10353 T10390 themeOf RIP1,inhibitors
R6733 T10354 T10391 themeOf TNFα,mRNA
R6734 T10355 T10392 themeOf bFGF,stimulated
R6735 T10356 T10393 themeOf TNFα,synthesis
R6736 T10357 T10358 themeOf phosphorylation,increase
R6737 T10357 T10358 themeOf phosphorylation,increase
R6738 T10357 T10358 themeOf phosphorylation,increase
R6739 T10357 T10358 themeOf phosphorylation,increase
R6740 T10357 T10358 themeOf phosphorylation,increase
R6741 T10363 T10364 themeOf activation,regulates
R6742 T10366 T10367 themeOf phosphorylation,block
R6743 T10367 T10368 themeOf block,required
R6744 T10371 T10372 themeOf synthesis,increased
R6745 T10373 T10374 themeOf synthesis,contribute
R6746 T10375 T10378 themeOf increase,dependent
R6747 T10376 T10377 themeOf levels,increased
R6748 T10379 T10380 themeOf induction,triggered
R6749 T10381 T10382 themeOf upregulation,increased
R6750 T10381 T10384 themeOf upregulation,caused
R6751 T10383 T10385 themeOf synthesis,increase
R6752 T10383 T10386 themeOf synthesis,autocrine
R6753 T10387 T10389 themeOf upregulation,contribute
R6754 T10390 T10394 causeOf inhibitors,effect
R6755 T10391 T10394 themeOf mRNA,effect
R6756 T10393 T10395 themeOf synthesis,increase
R6757 T10395 T10396 themeOf increase,mediate
R6758 T10395 T10397 themeOf increase,necroptosis-dependent
R8233 T12418 T12430 themeOf TNFα,synthesis
R8234 T12419 T12432 themeOf TNFα,increase
R8235 T12420 T12433 themeOf Akt1,Knockdown
R8236 T12421 T12433 themeOf Akt2,Knockdown
R8237 T12422 T12434 themeOf c-Jun,phosphorylation
R8238 T12423 T12435 themeOf RIP1,link
R8239 T12424 T12439 themeOf bFGF,increase
R8240 T12425 T12440 themeOf c-Jun,phosphorylation
R8241 T12426 T12445 themeOf c-Jun,phosphorylation
R8242 T12427 T12443 themeOf p70S6K,Knockdown
R8243 T12427 T12444 themeOf p70S6K,inhibitor
R8244 T12428 T12448 themeOf S6K,acting
R8245 T12430 T12431 themeOf synthesis,regulator
R8246 T12433 T12436 causeOf Knockdown,suppressed
R8247 T12433 T12436 causeOf Knockdown,suppressed
R8248 T12433 T12436 causeOf Knockdown,suppressed
R8249 T12433 T12436 causeOf Knockdown,suppressed
R8250 T12434 T12436 themeOf phosphorylation,suppressed
R8251 T12434 T12437 themeOf phosphorylation,increase
R8252 T12434 T12436 themeOf phosphorylation,suppressed
R8253 T12437 T12438 themeOf increase,dependent
R8254 T12437 T12436 themeOf increase,suppressed
R8255 T12437 T12436 themeOf increase,suppressed
R8256 T12438 T12437 themeOf dependent,increase
R8257 T12439 T12441 themeOf increase,delayed
R8258 T12440 T12442 themeOf phosphorylation,induced
R8259 T12441 T12439 themeOf delayed,increase
R8260 T12443 T12447 causeOf Knockdown,attenuated
R8261 T12443 T12447 causeOf Knockdown,attenuated
R8262 T12444 T12443 themeOf inhibitor,Knockdown
R8263 T12445 T12446 themeOf phosphorylation,increase
R8264 T12446 T12447 themeOf increase,attenuated
R8265 T12446 T12447 themeOf increase,attenuated
R8789 T13227 T13233 causeOf 3-phosphoinositide dependent protein kinase-1,phosphorylated
R8790 T13228 T13233 themeOf PDK1,phosphorylated
R8791 T13230 T13234 themeOf PDK1,Inhibition
R8792 T13231 T13236 themeOf PDK1,knockdown
R8793 T13232 T13237 themeOf PDK1,required
R8794 T13234 T13235 themeOf Inhibition,resulted
R9949 T15101 T15144 themeOf Akt1,expressing
R9950 T15102 T15144 themeOf Myr-Akt,expressing
R9951 T15103 T15144 themeOf K179M,expressing
R9952 T15107 T15145 themeOf Myr-Akt,expressing
R9953 T15111 T15146 themeOf c-Jun,phosphorylation
R9954 T15112 T15147 themeOf TNFα,upregulation
R9955 T15115 T15149 themeOf RIP1,phosphorylation
R9956 T15116 T15149 themeOf Myr-Akt,phosphorylation
R9957 T15118 T15151 themeOf Myr-Akt,expression
R9958 T15119 T15151 themeOf K179M,expression
R9959 T15120 T15153 themeOf Myr-Akt,increased
R9960 T15121 T15154 themeOf p70S6K,phosphorylated
R9961 T15122 T15154 themeOf S6,phosphorylated
R9962 T15123 T15154 themeOf FoxO4,phosphorylated
R9963 T15124 T15155 themeOf FoxO1,phosphorylation
R9964 T15125 T15155 themeOf MDM2,phosphorylation
R9965 T15126 T15157 themeOf Myr-Akt,phosphorylation
R9966 T15127 T15158 themeOf TNFα,production
R9967 T15128 T15159 themeOf Myr-Akt,expressed
R9968 T15129 T15160 themeOf Akt,reduction
R9969 T15130 T15161 themeOf S473D mutant,phosphorylated
R9970 T15132 T15162 themeOf S473A,phosphorylated
R9971 T15133 T15163 themeOf PDK1,phosphorylate
R9972 T15134 T15165 themeOf c-Jun,phosphorylation
R9973 T15135 T15164 themeOf TNFα,promoting
R9974 T15136 T15166 themeOf T308D,phosphorylation
R9975 T15137 T15167 themeOf T308D,phosphorylation
R9976 T15138 T15168 themeOf Myr-Akt,phosphorylated
R9977 T15139 T15168 themeOf FoxO1,phosphorylated
R9978 T15140 T15168 themeOf Foxo4,phosphorylated
R9979 T15141 T15168 themeOf MDM2,phosphorylated
R9980 T15142 T15168 themeOf p70S6K,phosphorylated
R9981 T15146 T15148 themeOf phosphorylation,activation
R9982 T15146 T15147 themeOf phosphorylation,upregulation
R9983 T15147 T15148 themeOf upregulation,activation
R9984 T15147 T15148 themeOf upregulation,activation
R9985 T15149 T15150 themeOf phosphorylation,kinase-dependent
R9986 T15149 T15150 themeOf phosphorylation,kinase-dependent
R9987 T15151 T15152 themeOf expression,increased
R9988 T15151 T15152 themeOf expression,increased
R9989 T15155 T15156 themeOf phosphorylation,increased
R9990 T15155 T15156 themeOf phosphorylation,increased
R9991 T15165 T15164 themeOf phosphorylation,promoting